Molecules 1998, 3, M44
2-Cyanophenylbis(5-methylfur-2-yl)methane
Andrey V. Gutnov
North-Ossetian State University, RUS-362040 Vladikavkaz, Russian Federation.
Fax: +7 867 227 3216, E-mail: [email protected]
Received: 22 December 1997 / Published: 25 January 1998
The mixture of 2-bromophenylbis(5-methylfur-2-yl)methane [1] (16.55 g, 50 mmol), 5 g CuCN and 5 ml of dry pyridine was heated for 12 hr on the oil bath at 220deg.C, then cooled to 150deg.C and poured onto a mixture of 10 ml ethylenediamine in 100 ml of H2O and 100 ml of benzene. The mixture was refluxed for 3 hr, the emulsion was filtered, the benzene layer separated and after drying with Na2SO4 evaporated. The residue was dissolved in the boiling hexane and filtered through a pad of Al2O3. Cooling the hexane solution gave 5.15 g (37.14%) of golden needles.
M.p. 86-87deg.C.
1
H-NMR (CDCl3): 7.65-7.2 (m, 4H, HAr), 5.95 (d, 2H, 3-HFur), 5.83 (d, 2H, 4-HFur), 5.7 (s, 1H, CH), 2.2 (s, 6H, CH3) ppm.Anal. calc. for C18H15NO2 (277, 32): C 77.96, H 5.45, N 5.05; found: C 77.85, H 5.53, N 4.96.
Acknowledgment: The author would like to thank Mr. Vladimir T. Abaev and Mr. Alexandre V. Butin for their support.
References and Notes
1. Molecules 1997, 2, M28.
Sample Availability: 350 mg available from the authors.
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