Industrial Biotransformations. By Liese, Andreas / Seelbach, Karsten / Wandrey, Christian. Wiley-VCH, Weinheim , 2000. Pages: 423, Hardcover. Price: 213.19 DM / 109.- EUR / 189.- SFR. ISBN: ISBN 3-527-30094-5
Received: 1 December 2001
Industrial Biotransformations - a user-friendly and application-oriented up-to-date overview of one-step biotransformations of industrial importance.
The data conferring each process is arranged in a convenient format to survey so that the processes can easily be compared. Each set of data is accompanied by key literature citations. As far as flow sheets of the processes are available, these are given reduced to their significant elements. An extensive index classified by substrates, products, enzymes, and companies provides direct access to each process organized in the order of enzyme classes. The reader will find all significant parameters characterizing the biotransformation itself and the process.
Data collection. Structured description of processes according to the following scheme:
Product
Reaction Scheme
Reaction Conditions
Flow Scheme
Process Parameters
Product Application
Remarks
References
Table of Contents:
1 Introduction 1
2 History of Industrial Biotransformations -- Dreams and Realities 3
2.3 Advantages of biotransformations over classical chemistry 25
References 27
3 Enzyme Classification 31
3.1 The Enzyme Nomenclature 31
3.2 The Enzyme Classes 33
EC 1 Oxidoreductases 34
EC 2 Transferases 39
EC 3 Hydrolases 43
EC 4 Lyases 48
EC 5 Isomerases 51
EC 6 Ligases 54
References 56
4 Basics of Bioreaction Engineering 57
4.1 Definitions 58
4.2 Biosynthesis and immobilization of biocatalysts 64
4.3 Characteristics of the different enzyme classes 79
4.4 Kinetics 83
4.5 Basic reactor types and their mode of operation 86
References 90
5 Processes 93
(Selection)
Alcohol dehydrogenase Rhodococcus erythropolis 103
Leucine dehydrogenase Bacillus sphaericus 125
Nicotinic acid hydroxylase Achromobacter xylosoxidans 131
Lipase Burkholderia plantarii 181
Lactonase Fusarium oxysporum 220
Penicillin amidase Escherichia coli 283
Penicillin acylase Escherichia coli 290
Aminoacylase Aspergillus oryzae 300
Asparte .beta.-decarboxylase Pseudomonas dacunhae 334
Fumarase Brevibacterium flavum 347
Nitrile hydratase Rhodococcus rhodochrous 362
Xylose isomerase Bacilluscoagulans/Strptomyces rubiginosus/Streptomyces phaechromogenes 387
Dear reader 393
Index
Index of enzyme name 397
Index of strain 400
Index of company 403
Index of starting material 406
Index of product
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