Special Issue: "Cantilever, Microcantilevers and Nanocantilever Sensors and Biosensors" - Sensors Journal

Guest Editors
Dr. M. Calleja and Dr. J. Tamayo
Biosensor Group
E-mail: mcalleja@imm.cnm.csic.es; jtamayo@imm.cnm.csic.es; http://www.imm.cnm.csic.es/BioNanoMech/

Published Papers

Yu-Lin Guo, Jia Zhou*, Yiping Huang and MinHang Bao
ASIC and System National Key Lab, Department of Microelectronics, Fudan University, Shanghai 200433, China
E-mail: 042052033@fudan.edu.cn. Jia.zhou@fudan.edu.cn. yphuang@fudan.edu.cn. mhbao@fudan.edu.cn
* Corresponding author.
Received: 24 July 2007 / Accepted: 30 August 2007 / Published: 3 September 2007
Full Paper: Modeling of photoinduced deformation in silicon microcantilever
Sensors 2007, 7, 1713-1719 (PDF format, 308 K)

Daniel Ramos, Johann Mertens, Montserrat Calleja and Javier Tamayo*
BioNanoMechanics Lab, National Centre for Microelectronics, IMM-CNM, CSIC Isaac Newton 8 (PTM), Tres Cantos 28760, Madrid, Spain
* Author to whom correspondence should be addressed. E-mail: jtamayo@imm.cnm.csic.es
Received: 30 July 2007 / Accepted:31 August 2007 / Published: 5 September 2007
Communication: Study of the origin of bending induced by bimetallic effect on microcantilever
Sensors 2007, 7, 1757-1765 (PDF format, 114 K)

Daniel Ramos 1, Montserrat Calleja 1,*, Johann Mertens 1, A. Zaballos 2 and Javier Tamayo 1
1 BioNanoMechanics Lab, National Centre for Microelectronics, IMM-CNM, CSIC, Isaac Newton 8 (PTM), Tres Cantos 28760, Madrid, Spain
2 Genomics Functional Unit, Department of Immunology and Oncology, CNB-CSIC, Darwin 3, Madrid 28049, Spain
* Author to whom correspondence should be addressed. E-mail: mcalleja@imm.cnm.csic.es
Received: 27 July 2007 / Accepted: 6 September 2007 / Published: 7 September 2007
Full Research Paper: Measurement of the Mass and Rigidity of Adsorbates on a Microcantilever Sensor 
Sensors 2007, 7, 1834-1845 (PDF format, 242 K)

Gino Rinaldi, Muthukumaran Packirisamy * and Ion Stiharu
Optical Microsystems Laboratory, CONCAVE Research Center Department of Mechanical & Industrial Engineering, Concordia University, Montreal, CANADA H3G 1M8
E-mail: grin@alcor.concordai.ca; pmuthu@alcor.concordia.ca; istih@alcor.concordai.ca
* Author to whom correspondence should be addressed.
Received: 6 September 2007 / Accepted: 26 September 2007 / Published: 3 October 2007

Communication: Quantitative Boundary Support Characterization for Cantilever MEMS
Sensors 2007, 7, 2062-2079 (PDF format, 1100 K)

Yu-Hsiang Wang 1, Chia-Yen Lee 1,* and Che-Ming Chiang 2
1 Department of Mechanical and Automation Engineering, Da-Yeh University, Changhua, Taiwan
2 Department of Architecture, National Cheng Kung University, Tainan, Taiwan 701
* Author to whom correspondence should be addressed.
Received: 27 August 2007 / Accepted: 15 October 2007 / Published: 17 October 2007

Full Research Paper: A MEMS-based Air Flow Sensor with a Free-standing Micro-cantilever Structure
Sensors 2007, 7, 2389-2401  (PDF format, 2180 K)

Liling Fu 1, Suiqiong Li 1, Kewei Zhang 1, I-Hsuan Chen 2, Valery. A. Petrenko 2 and Zhongyang Cheng 1,*
1 Materials Research and Education Center, Auburn University, Auburn, AL 36849
2 Department of Pathobiology, Auburn University, Auburn, AL 36849
* Author to whom correspondence should be addressed. Email: chengzh@eng.auburn.edu.
Received: 18 October 2007 / Accepted: 21 November 2007 / Published: 22 November 2007

Full Research Paper: Magnetostrictive Microcantilever as an Advanced Transducer for Biosensors
Sensors 2007, 7, 2929-2941  (PDF format, 840 K)

Seonghwan Kim 1, Kyung Chun Kim 2 and Kenneth David Kihm 1,*
1 Department of Mechanical, Aerospace, and Biomedical Engineering, University of Tennessee, Knoxville, Tennessee, USA 37996
2 School of Mechanical Engineering, MEMS/Nano Fabrication Center, Pusan National University, Busan 609-735, Korea
* Author to whom correspondence should be addressed. E-mail: kkihm@utk.edu
Received: 1 November 2007 / Accepted: 4 December 2007 / Published: 6 December 2007 

Full Research Paper: Near-Field Thermometry Sensor Based on the Thermal Resonance of a Microcantilever in Aqueous Medium
Sensors 2007, 7, 3156-3165 (PDF format, 258 K)

Marc Hennemeyer, Stefan Burghardt and Robert W. Stark *
Ludwig-Maximilians-Universität München, Center for NanoScience (CeNS) and Dept. Earth and Environmental Sciences, Theresienstrasse 41, 80333 Munich, Germany
Web: http://www.nanobiomat.de; E-mail: marc@hennemeyer.de; stark@lrz.uni-muenchen.de
* Author to whom correspondence should be addressed.
Received: 29 October 2007 / Accepted: 4 January 2008 / Published: 9 January 2008
Full Research Paper: Cantilever Micro-rheometer for the Characterization of Sugar Solutions
Sensors 2008, 8, 10-22 (PDF format, 3470 K)

Lorenz J. Steinbock and Mark Helm *
Department of Chemistry, Institute of Pharmacy and Molecular Biotechnology, University of Heidelberg, Im Neuenheimer Feld 364, 69120 Heidelberg, Germany
* Author to whom correspondence should be addressed. (mark.helm@urz.uni-heidelberg.de)
Received: 31 October 2007 / Accepted: 2 January 2008 / Published: 

Full Research Paper: Wavelength Dependence of Photoinduced Microcantilever Bending in the UV-VIS Range
Sensors 2008, 8, 23-34 (PDF format, 239 K)

Open Access
Maria Nordström 1,*, Stephan Keller 1, Michael Lillemose 1, Alicia Johansson 2, Søren Dohn 1, Daniel Haefliger 3, Gabriela Blagoi 1, Mogens Havsteen-Jakobsen 1 and Anja Boisen 1
1 MIC – Department of Micro and Nanotechnology, Technical University of Denmark, DTU building 345 East, DK-2800 Kongens Lyngby, Denmark
2 Now at PhotoSolar ApS, Denmark
3 Now at HARTING Mitronics AG, Switzerland
* Author to whom correspondence should be addressed; E-mail: man@mic.dtu.dk
Received: 2 November 2007 / Accepted: 3 March 2008 / Published: 10 March 2008

Full Research Paper: SU-8 Cantilevers for Bio/chemical Sensing; Fabrication, Characterisation and Development of Novel Read-out Methods
Sensors 2008, 8, 1595-1612 (PDF format, 659 K)

Open Access
Eric Finot 1,*, Ali Passian 2,3 and Thomas Thundat 2,3
1 Institut Carnot de Bourgogne, UMR 5209 CNRS-Université de Bourgogne, 9 Av. A. Savary, BP 47 870, F-21078 Dijon Cedex, France
2 Nanoscale Science and Devices, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA
3 Department of Physics, University of Tennessee, Knoxville, TN 37996, USA; E-mails: passianan (a) ornl.gov; thundattg (a) ornl.gov
* Author to whom correspondence should be addressed; E-mail: Eric.Finot (a) u-bourgogne.fr
Received: 17 April 2008 / Accepted: 18 May 2008 / Published: 26 May 2008
Review: Measurement of Mechanical Properties of Cantilever Shaped Materials
Sensors 2008, 8, 3497-3541 (PDF format, 545 K) DOI: 10.3390/s8053497

Open Access
Dirk Sander *, Zhen Tian and Jürgen Kirschner
Max-Planck-Institut für Mikrostrukturphysik,Weinberg 2, D-06120 Halle, Germany; E-mail: (sander@mpi-halle.de).
* Author to whom correspondence should be addressed.
Received: 4 March 2008; in revised form: 16 May 2008 / Accepted: 16 May 2008 / Published: 29 July 2008

Article: Cantilever measurements of surface stress, surface reconstruction, film stress and magnetoelastic stress of monolayers
Sensors 2008, 8, 4466-4486 (PDF format,  K) DOI: 10.3390/s8074466


In the last years, microcantilevers have been increasingly used as mechanical transducers of molecular recognition and for the development of miniaturized and sensitive biochip platforms. The principle is that intermolecular forces that result from molecular recognition events on the sensitised surface of a cantilever produce its nano-scale motion. Main techniques for the nanomechanical response include the optical lever method, interferometry-based methods, and the piezoresistivity technique. The optical lever method is the most extended due to the extreme accuracy and easy implementation for measuring cantilevers immersed in liquids. The applications include detection of cancer protein markers, pesticides, DNA hybridisation and pathogens. The great interest in these recent kind of biosensors relies on the label-free detection, high sensitivity, small sensor area, and the potential for simultaneous detection of tens, or even hundreds, of targets by making use of arrays of cantilevers. In fact, cantilever arrays can be mass-fabricated at low cost by adopting well-known semiconductor technology. Also, with microelectronics technology now pushing deep into the submicron regime, nanoelectromechanical systems (NEMS) are drawing interest from the scientific community for a wide range of applications due to their unique properties. Nanocantilevers are among those of the possible NEMS realizations that offer access to a parameter space that is unprecedented; fundamental resonant frequencies in the microwaves, active masses in the femtograms, heat capacities below a yoctocalorie, to name a few. Nanocantilever resonators have been proposed for ultrafast sensors and actuators, signal processing components and for quantum computing. Recent experiments have open up a new application, mass detection based on  nanoresonators. The minuscule active mass of this elements allow to envision the detection of single molecules.



Microcantilever-Based Biosensors, Surface Stress Measurements, Mass Detection, Microcantilevers, Nanocantilevers, nano-micromechanical resonators, nanomechanical sensors, nanomechanics, NEMS, MEMS, nanoresonators

Mr. Matthias Burkhalter
Managing Editor
MDPI Center - Sensors Office
Kandererstrasse 25 - CH-4057 Basel / Switzerland
E-mail: sensors@mdpi.org
Tel +41 61 683 7734, Fax +41 61 302 8918

Sensors Journal Special Issues


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MDPI - Matthias Burkhalter -  16 July 2008