Virtual Editorial Center

Honorary Editor in Chief
Prof. Dr. Árpád Furka
Professor, Ph.D., D.Sc.
Eötvös Loránd University, Department of Organic Chemistry
H-1518 Budapest 112, P.O. Box 32
Phone: (36-1) 209-0555, Fax: (36-1) 372-2620, e-mail: [email protected]
Home page: http://szerves.chem.elte.hu/Furka

Editor in Chief
Dr. Shu-Kun Lin
Molecular Diversity Preservation International (MDPI)
Saengergasse 25, CH-4054 Basel, Switzerland
Tel. +41 79 322 3379, Fax +41 61 302 8918
E-mail: [email protected]
http://www.mdpi.org/lin/

Research proposals and new ideas
Dr. Andrew P. Combs, E-mail: [email protected]

Editorial Board

Dr. Charles J. Andres
Senior Research Investigator, Early Discovery Chemistry, Bristol-Myers Squibb Pharmaceutical Research Institute, 5 Research Parkway, Wallingford, CT 06492  USA
Phone:  203-677-6219, Fax:  203-677-7702
E-mail: [email protected]
Key words: Combinatorial, Parallel, Synthesis, Medicinal, Chemistry

Dr. Mark R. Ashton
Director of Discovery Services
Oxford Asymmetry International
111 Milton Park, Abingdon, Oxon, OX14 4SD, UK
Tel:  + 44 (0)1235 441236/441200
Fax: + 44 (0)1235 441509
E-mail: [email protected]
http://www.oai.co.uk/
Key words: Combinatorial chemistry, Drug discovery, Medicinal chemistry, Molecular diversity, Solid and solution phase chemistry

Dr. Neerja Bhatnagar
Head, Automated Synthesis and New Technologies
Aventis Pharma
102 Route de Noisy
93235 Romainville Cedex
France
Tel : (33)-1-4991.4307
Fax : (33)-1-4991.3089
E-mail: [email protected]
Key words: Parallel Synthesis, Solid phase chemistry, Solution Phase Chemistry, Automation, libraries Please do not hesitate to contact me for any further questions.

Dr. Sukanta Bhattacharyya
Argonaut Technologies
887 Industrial Road, Suite
G, San Carlos, CA 94070
USA
Tel: 650-598-1350 x 311
Fax: 650-598-1359
E-mail: [email protected]
Key Research words: Automated and Semi-automated Parallel Synthesis, Synthetic Methods, Solid and Solution-phase Synthesis, Bound reagents

Dr. Jose I. Borrell
Institut Quimic de Sarria
Universitat Ramon Llull
Via Augusta 390
08017 Barcelona (Spain)
tel: 34-93.203.89.00 ext 2354
fax: 34-93.205.62.66
e-mail: [email protected]
http://www.iqs.url.es

Dr. J. Guy Breitenbucher
Synthesis section
Hit-to-Lead Group Leader
R.W. Johnson PRI
3210 Merryfield Row
San Diego, CA 92121, USA
(858) 784-3036
FAX:  (858) 450-2089
E-mail: [email protected]
Key words: Solid phase organic synthesis, Solution phase library synthesis, Library purification and analysis, Protease inhibition, Kinase inhibition, general organic synthesis

Dr. Barry A. Bunin
President
Libraria, Inc.
692 Los Padres Blvd
San Bruno, CA 94066
Tel-408-383-0790
Fax-408-383-0799
E-mail: [email protected]
Key words: 1,4-benzodiazepine libraries, Combinatorial Index, informatics-based approach

Dr Weng C. Chan
School of Pharmaceutical Sciences,
University of Nottingham, University Park, Nottingham
NG7 2RD
England
Tel: +44 (0)1159515080.  Fax: +44 (0)1159515078.
E-mail: [email protected]
Keywords: Solid-phase peptide synthesis; solid-phase organic, chemistry; Combinatorial chemical biology; Antibacterial agents; Anti-tumor agents.

Dr. Andrew P. Combs
Director C&PS
DuPont Pharmaceuticals Co.
Experimental Station, E500/1604B
Wilmington, DE 19880-0500
USA
Tel: (302)-695-9707
Fax: (302)-695-4390
E-mail: [email protected]
Keywords: solid-phase synthesis, polymer assisted solution phase synthesis, microwave assisted organic synthesis, target directed libraries,  new synthetic methodologies for parallel synthesis

Prof. Dr. William F. DeGrado
Department of Biochemistry & Biophysics
University of Pennsylvania
School of Medicine
Philadelphia, PA 19104-6059
36th & Hamilton Walk
USA
Phone 215 898 4590
Fax  215 573 7229
E-mail: [email protected]
Keywords: Protein Structure, Protein Design, Phage Display, Peptides, De novo design.

Dr. Sunita M. deSousa
AstraZeneca India Pvt. Ltd.
277 T. Chowdaiah Rd.
Malleswaram
Bangalore 560 003
India
tel     : 91-80)-334 0372 or (91-80)-334 5118
fax     :(91-80)-334 0449
Email:  [email protected]
Keywords: Drug discovery, Antibacterial agents, Target identification and validation, Assay development
 

Dr. Andrew J. de Mello  PhD, ARCS, DIC, MRSC, CChem
AstraZeneca Lecturer of Analytical Sciences
AstraZeneca / SmithKline Beecham Centre for Analytical Sciences
Department of Chemistry
Imperial College of Science, Technology & Medicine
Exhibition Road, South Kensington
London SW7 2AY
England
Tel. +44 207 594 5820
fax +44 207 594 5833
Room 204, RCS1 (Old Chemistry)
E-mail: [email protected]
http://www.achem.ic.ac.uk/or http://www.streetmap.co.uk/streetmap.dll?grid2map?X=526750&Y=179250
Keywords: microsystems, new synthetic methodologies for solution phase synthesis, lab-on-a-chip, detection techniques, optical spectroscopy

Dr. Gabor Dibo
Associate Professor
Eotvos University, Department of Organic Chemistry
PO Box 32, Budapest 112,
Hungary, H-1518
Ph: +36-1-372-2771; Fax: +36-1-372-2620
E-mail: [email protected]  or  [email protected]
Keywords: molecular diversity, peptide library, split-mix synthesis, 2 dimensional planar chromatography, capillary electrophoresis

Dr. Eduard Felder
Department of Chemistry, Discovery Research Oncology, Pharmacia & Upjohn S.p.A. Viale Pasteur 10, I-20014 Nerviano (MI),
Italy.
Tel. 0039-02-48385233, fax 0039-02-48383937
E-mail: [email protected]
Keywords: Organic synthesis, combinatorial chemistry

Dr. Susannah Gal
Associate Professor
Department of Biological Sciences
The State University of New York
Vestal Parkway East
Binghamton, NY 13902-6000
USA
(607) 777-4448  office
(607) 777-6521  FAX
E-mail: [email protected]
Keywords: Cell Biology, Molecular Genetics, Proteases, Protein-DNA interactions,  Screening Strategies

Dr. C. John Harris, CChem FRSC
Technical Director
BioFocus plc
Sittingbourne Research Centre
Sittingbourne
KENT ME9 8AZ
UK
Tel: +44(0)1795-412300
Fax:+44(0)1795-471123
E-mail: [email protected]
www.biofocus.co.uk
Keywords: Combinatorial chemistry; medicinal chemistry; libraries; kinases; GPCRs

Dr. Pauline Gee
President and Chief Executive Officer
Xenometrix, Inc.
2425 North 55th Street, Suite 111
Boulder, CO 80301-5700
Tel:  (303) 447-1773 ext. 105
Fax: (303) 447-1758
E-mail: [email protected]
Key words: gene expression profiling, safety , predictive toxicity, molecular diversity as described by biological responses, mutagenicity

Prof. Dr. Guenther Jung
Institute of Organic Chemistry
University of Tuebingen
Auf der Morgenstelle 18
72076 Tuebingen
Germany
Tel. +49-(0)7071-29 76925 or 29 76239
Fax: +40-(0)7071-29 5560
E-mail: [email protected]
http://www.uni-tuebingen.de/jung
Key words: method developments in combinatorial organic synthesis, heteroacyclic and peptide chemistry, analytical methods (HPLC-MS, ICR-MS, IR-microscopy), synthetic receptors, lead structure search and optimization.

Dr Gyorgy M. Keseru
Unit Head, Computer Assited Drug Discovery
Gedeon Richter Ltd.
H-1103 Budapest
Gyomroi ut 19-21
P.O. Box: 27 H-1475
Hungary
E-mail: [email protected]
Key words: library design, combinatorial IT, structural biochemistry, computational, chemistry, molecular modelling

Dr. Albert P. Li
Chief Scientific Officer
In Vitro Technologies, Inc.
1450 S. Rolling Rd.
Baltimore, MD 21227
USA
(410)455-1252 (phone)
(410)455-1245 (fax)
Email:  [email protected]
Key words: Drug Metabolism; Toxicology; In Vitro Systems; Human Cell Culture; Hepatocytes

Dr. Andreas Marzinzik
Program Head - ICLF
Novartis Pharma AG
K-136.321 Postfach
CH-4002 Basel
Switzerland
phone: ++41 61 69 63553
fax: ++41 61 69 68360
E-mail:  [email protected]
Key words: Organic synthesis, combinatorial chemistry

Masato Mitsuhashi, M.D., Ph.D.
Vice president, Chief Scientific Officer, Hitachi Chemical Research Center
President, Chief Executive Officer, RNAture, Inc.
1003 Health Sciences Road West
Irvine, CA 92612
USA
TEL: 949-725-2795, FAX: 949-725-2727
E-mail:  [email protected]
web: www.RNAture.com
Key words: mRNA, gene expression, microplate, RT-PCR, automation

Dr. Ilya Okun
Vice President of Cell Pharmacology
AXIOM Biotechnologies, Inc.
3550 General Atomics Court
San Diego, CA 92121
USA
Tel. (619) 455-4458
Fax (619) 455-4501
E-mail: [email protected]
http://www.axiombio.com
Key words: Cell pharmacology, G protein-coupled receptors, ion channels, and signal transduction pathways

Dr. Kevin R. Oldenburg
MatriCal, Inc.
6 LaFayette Place
Chadds Ford, PA 19317
USA
Phone 610-361-8867
FAX 610-361-8867
E-mail: [email protected]
http://www.MatriCal.com
Key words: High Throughput Screening, Technology Development, Engineering, Biophysics, Combinatorial Chemistry

Dr. Jesus Vicente de Julián Ortiz
Institut de Química Computacional, Facultat de Ciències, Universitat de Girona, Campus de Montilivi, 17071 Girona, Spain
Tel +34 - 972 418 367, Fax +34 - 972 418 356
e-mail [email protected]
http://iqc.udg.es
Key words: Molecular diversity generation, computational chemistry

Dr. Richard M. Nelson
Senior Principal Scientist
BioMolecular Screening Group
Medicinal Chemistry Department
Boehringer Ingelheim Pharmaceuticals, Inc.
900 Ridgebury Rd./P.O. Box 368
Ridgefield, CT 06877-0368
USA
Tel.:  203-798-4509
Fax:  203-791-6072
E-mail:  [email protected]
Key words: HTS and ultra-high throughput screening assay development for drug discovery, assay automation and robotics, molecular binding interactions, decision analysis for drug discovery

Dr. Pierfausto Seneci
Director, Chemistry
Nucleotide Analog Pharma AG
Landsbergerstrasse 50
80339 München
Germany
E-mail: [email protected]
tel: +49-89-50808230
fax: +49-89-50808279
Key words: Solid-phase Synthesis, Combinatorial Chemistry, Medicinal Chemistry, Diversity, Drug Discovery

Mr. Pirthipal Singh
Associate Team Leader
AstraZeneca UK Ltd
Alderley Park
Macclesfield
Cheshire
SK10 4TG
England (UK)
Telephone: +44 (0)1625 516640
Fax: +44 (0)1625 513441
E-mail: [email protected]
Key words: Assay Design & Development, Biochemical Assays, Advanced Assay Technologies, Imaging Instrumentation, Methods for HTS follow-up & Secondary Screening.

Dr. G. Sitta Sittampalam
Senior Research Scientist & Group Leader
Bio-Research Technologies Division
Lilly Research Labortories
Eli Lilly & Company
Indianapolis, IN, 46285
USA
317-276 6554 (tel)
317 -433 6963 (fax)
E-mail: [email protected]
Key words: Assay development, Diversity, Signal transduction, Biochemical assays, Kinetics

Dr. Irving Sucholeiki
President of Solid Phase Sciences Corporation, 550 Boston Avenue, 2nd Floor, Medford, MA 02155, USA
Phone: 781-396-6444, FAX: 781-396-2615
http://www.sps-c.com
E-mail: [email protected]
Key words: Solid-phase synthesis, supports, linkers, drug discovery.

Dr. Georg C. Terstappen
Head, Molecular Biology & Biochemistry Unit
GlaxoWellcome Medicines Research Centre
Via A. Fleming, 4
37135 Verona
Italy
Phone: ++045-9218-957
Fax:++045-9218-047
E-mail: [email protected]
Key words: Bioassay Design, Biomolecular Screening, Ion Channels, GPCRs, Exploratory Research CNS

Dr. Dmytro O. Tymoshenko
Senior Research Chemist - Combinatorial Chemistry
Medicinal Chemistry Department
Albany Molecular Research, Inc.
21 Corporate Circle
P.O. Box 15098
Albany, New York 12212-5098
USA
Tel. (518) 464-0279, Ext. 2425
Fax. (518) 257-2019
E-mail: [email protected]
Key words: reactive polymers, combinatorial chemistry, heterocycles.

Dr. Mervi Vasänge
Section manager Biochemistry, Assay Development and Screening
Pharmacia
Strandbergsg 49,
112 87 Stokholm
Sweden
phone 46 18 165507
fax 46 18 166352
E-mail: [email protected]
http://www-i.se.pnu.com/
Key words: Hit-to-lead, assay development, high-throughput screening, enzyme assays, receptors

Hugo O. Villar
Vice President, Discovery Technologies
Telik, Inc.
750 Gateway Blvd.
South San Francisco, CA 94080
USA
Tel. 650-238-3309
Fax 650-244-9388
E-mail:  [email protected]
http://www.telik.com/officers.html
Key words: library design, virtual screening, in-silico ADME predictions

Dr. Helma Wennemers
Institute of Organic Chemistry
St. Johanns Ring 19
CH-4056 Basel
Switzerland
Tel: +00 41 61 267 11 46
FAX: +00 41 61 267 11 05
E-mail: [email protected]
http://www.chemie.unibas.ch/~wennemer/
Key words:  molecular recognition, combinatorial chemistry, peptides, receptors, artificial peptidases

Dr. David R. Webb
Vice President Discovery Research
OSI Pharmaceuticals, Inc.
106 Charles Lindbergh Blvd.
Uniondale, NY 11553
USA
Tel. 001 516-222-0023
FAX:  516-745-6429
E-mail: [email protected]
http://www.osip.com
Key words:  genomics, proteomics, GPCRs, HTS, immunology

Dr. J. Blair West
Director, Pharmaceutical Chemistry
Bend Research, Inc.
64550 Research Rd.
Bend, OR 97701
USA
Tel. 541-382-4100
fax 541-382-2713
E-mail [email protected]
Key words: drug discovery, diversity, high-energy compound generation

Dr. Lorenzo Williams
SINTEF Applied Chemistry,
Organic Synthesis
P.O. Box 124 Blindern
N-0314 Oslo
Norway
Tel: +47 22 06 79 20 (dir.), Mob: +47 93 43 43 75
Fax: +47 22 06 73 50
E-mail: [email protected]
http://www.sintef.no/     http://www.sintef.no/units/chem/orgsyn/
Key words: Microwave assisted synthesis, Monodisperse polymers/particles, mesoporous and macroporous supports, Chemistry validation, Planar synthesis and separation techniques, Bioutographical screening methods

Dr. Lebl, Michal
Michal Lebl, PhD, DSc
Senior Director of Automation
Illumina, Inc. & Spyder Instruments, Inc.
9885 Towne Centre Drive
San Diego, CA 92121-1975
phone 858 202 4504
fax 858 202 4680
E-mail: [email protected]