Marine Drugs: Volume 4, 2006, Table of Contents

(open access to this paper was granted by MDPI)
Hesham Fahmy ^1,*, Jordan K. Zjawiony ^2,*, Takao Konoshima ³, Harukuni Tokuda ⁴, Shabana Khan ⁵, and Sherief Khalifa ⁶
1 Department of Pharmaceutical Sciences, South Dakota State University, Box 2202C, Brookings, SD 57007, USA.
Tel.: 605-688-4243, Fax 605-688-5993, E-mail: [email protected]
2 Department of Pharmacognosy and National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, University, MS 38677-1848, USA.
Tel.: 662-915-7290, Fax: 662-915-6975; E-mail: [email protected]
3 Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan
4 Department of Molecular Biochemistry, Kyoto Prefectural University of Medicine, Kawaramachidori, Kamigyo-Ku, Kyoto 602-0841, Japan
5 National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The University of Mississippi, University, MS 38677-1848, USA
6 Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt
* Authors to whom correspondence should be addressed
Potent Skin Cancer Chemopreventing Activity of Some Novel Semi-synthetic Cembranoids from Marine Sources
Mar. Drugs 2006, 4, 28-36 (PDF format 83 K)

Special Issue: Marine Drugs and Ion Channels
Guest Editors: Hugo Rub�n Arias

Hugo R. Arias
Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California 91766, USA
Tel. (909) 469-5424, Fax (909) 469-5600, E-mail: [email protected]
Review: Marine Toxins Targeting Ion Channels
Mar. Drugs 2006, 4, 37-69 (PDF format 361 K)

(open access to this paper was granted by MDPI)
Shanta M. Messerli and Robert M. Greenberg *
Marine Biological Laboratory, 7 MBL Street, Woods Hole, MA 02543, USA
Tel: 508 289-7981. E-mail: [email protected]
* Author to whom correspondence should be addressed.
Review: Cnidarian Toxins Acting on Voltage-Gated Ion Channels
Mar. Drugs 2006, 4, 70-81 (PDF format 97 K)

Graham M. Nicholson ^1,* and Richard J. Lewis ²
1 Neurotoxin Research Group, Department of Health Sciences, University of Technology, Sydney, PO Box 123, Broadway NSW 2007, Australia. Tel. 61 02 9514 2230. Fax 61 02 9514 2228.
E-mail: [email protected]
2 Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia
* Author to whom correspondence should be addressed.
Review: Ciguatoxins: Cyclic Polyether Modulators of Voltage-gated Iion Channel Function
Mar. Drugs 2006, 4, 82-118 (PDF format 502 K)

(open access to this paper was granted by MDPI)
Richard T. Layer ^1,* and J. Michael McIntosh ²
1 Cognetix, Inc., 421 Wakara Way, Suite 201, Salt Lake City, UT 84108, USA
Phone: (801) 581-0400, Fax: (801) 581-9555, E-mail: [email protected]
2 Department of Psychiatry and Department of Biology, University of Utah, 257 S. 1400 E., Salt Lake City, UT 84112, USA
Phone: (801) 585-3622, Fax: (801) 585-5010, E-mail: [email protected]
* Author to whom correspondence should be addressed.
Review: Conotoxins: Therapeutic Potential and Application
Mar. Drugs 2006, 4, 119-142 (PDF format 125 K)

Shana L. Geffeney ^1,2 and Peter C. Ruben ^1,*
1 Department of Biology, Utah State University, 5305 Old Main Hill, Logan, Utah, 84322-5305, USA
+01-435-797-2490 (voice), +01-435-494-1575 (fax), [email protected]
2 Present address: Department of Molecular and Cellular Physiology, Stanford University, 279 Campus
Drive, Beckman Center B115, Stanford, California, 94305, USA
* Author to whom correspondence should be addressed.
Review: The Structural Basis and Functional Consequences of Interactions Between Tetrodotoxin and Voltage-Gated Sodium Channels
Mar. Drugs 2006, 4, 143-156 (PDF format 91 K)

Ahmed Al-Sabi^#, Jeff McArthur ^#, Vitaly Ostroumov ^# and Robert J. French *
Hotchkiss Brain Institute and the Department of Physiology and Biophysics, University of Calgary,
3330 Hospital Drive N.W., Calgary, Alberta, Canada T2N 4N1
# These authors contributed equally to this article.
* Corresponding author: Tel: 1 403 220 6893. Fax: 1 403 283 8731. E-mail: [email protected]
Review: Marine Toxins That Target Voltage-gated Sodium Channels
Mar. Drugs 2006, 4, 157-192 (PDF format 925 K)

(open access to this paper was granted by MDPI)
Christina I. Schroeder and Richard J. Lewis*
Institute for Molecular Bioscience, The University of Queensland, St Lucia, 4072, QLD, Australia
E-mail: [email protected] (for Christina I. Schroeder)
* To whom correspondence should be addressed. Tel: +61-7-3346 2984; Fax: +61-7-3346 2101.
E-mail: [email protected]
Review: ω-Conotoxins GVIA, MVIIA and CVID: SAR and Clinical Potential
Mar. Drugs 2006, 4, 193-214 (PDF format 419 K)

(open access to this paper was granted by MDPI)
Lei Wen ^1,2, Sheng Yang ¹, Wenxia Zhou ¹, Yongxiang Zhang ^1,* and Peitang Huang ³
1 Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China
2 School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China
3 Beijing Institute of Biotechnology, Beijing 100071, China
* Author to whom correspondence should be addressed: Tel. (86)-10-66931625; Fax (86)-10-
68211656; E-mail: [email protected]
Review: New Conotoxin SO-3 Targeting N-type Voltage-Sensitive Calcium Channels
Mar. Drugs 2006, 4, 215-227 (PDF format 232 K)

(open access to this paper was granted by MDPI)
Susan Wonnacott ^1,* and Timothy Gallagher ²
1 Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, United Kingdom
E-mail: [email protected]
2 School of Chemistry, University of Bristol, Bristol BS8 1TS, United Kingdom
E-mail: [email protected]
* Author to whom correspondence should be addressed.
Review: The Chemistry and Pharmacology of Anatoxin-a and Related Homotropanes with respect to Nicotinic Acetylcholine Receptors
Mar. Drugs 2006, 4, 228-254 (PDF format 186 K)

William Kem ^1,*, Ferenc Soti ¹, Kristin Wildeboer ¹, Susan LeFrancois ¹, Kelly MacDougall ¹, Dong-Qing Wei ³, Kuo-Chen Chou ⁴ and Hugo R. Arias ²
1 Department of Pharmacology and Therapeutics, University of Florida, College of Medicine, Gainesville, FL 32610-0267, USA
2 Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766-1854, USA
3 College of Life Science and Technology, Shanghai Jiaotong University, Minhang District Shanghai, 200240, China
4 Gordon Life Science Institute, San Diego, CA 92130, USA
* Authors to whom correspondence should be addressed; Tel. (352) 392-3541; Fax (352) 392-9696; Email: [email protected]
Review: The Nemertine Toxin Anabaseine and Its Derivative DMXBA (GTS-21): Chemical and Pharmacological Properties
Mar. Drugs 2006, 4, 255-273 (PDF format 210 K)

Vipra Kundoor ¹, Xiaoying Zhang ¹, Sherief Khalifa ², Hesham Fahmy ^1,*, and Chandradhar Dwivedi ^1,*
1 Department of Pharmaceutical Sciences, South Dakota State University, Brookings, SD 57007, USA. Tel.: 605-688-4247, Fax 605-688-5993
2 Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt
* Author to whom correspondence should be addressed
Received: 28 July 2006 / Accepted: 18 August 2006 / Published: 21 August 2006

(open access to this paper was granted by MDPI)
Leonardo Castellanos ¹, Carmenza Duque ¹, Jaime Rodr�guez ² and Carlos Jim�nez ^2,*
1 Departamento de Qu�mica, Universidad Nacional de Colombia, AA 14490 Bogo �, Colombia
2 Departamento de Qu�mica Fundamental, Facultad de Ciencias, Campus da Zapateira Universidad de
A Coru�a, 15071 A Coru�a, Spain
* Author to whom correspondence should be addressed: Tel: +34-981167000 Ext. 2170, Fax: +34-981 167065; E-mail: [email protected]

Michio Namikoshi ^1,*, Takeshi Fujiwara ², Teruaki Nishikawa ³ and Kazuyo Ukai ¹
1 Tohoku Pharmaceutical University, Aoba-ku, Sendai 981-8558, Japan
E-mail: [email protected] (M. N.). E-mail: [email protected] (K. U.)
2 Department of Ocean Sciences, Tokyo University of Marine Science and Technology, Minato-ku, Tokyo 108-8477, Japan
E-mail: [email protected] (T. F.).
3 The Nagoya University Museum, Chikusa-ku, Nagoya 464-8601, Japan
E-mail: [email protected] (T. N.).
* Author to whom correspondence should be addressed. Tel., +81-22-727-0219; fax, +81-22-727-0218; e-mail, [email protected].
Received: 19 September 2006 / Accepted: 31 October 2006 / Published: 1 November 2006

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