Molecules: Volume 12, 2007, Table of Contents

Amjid Iqbal ¹, Hamid Latif Siddiqui ^1,*, C. M. Ashraf ², Matloob Ahmad ¹ and George. W. Weaver ³
1 Institute of Chemistry, University of the Punjab, Lahore-54590, Pakistan; E-mails: [email protected]; [email protected].
2 Department of Chemistry, Forman Christian College (A Chartered University) Lahore-54600, Pakistan; E-mail: [email protected]
3 Department of Chemistry, Loughborough University, Loughborough, LE 11 3TU, UK; E-mail: [email protected]
*Author to whom correspondence should be addressed; E-mail:([email protected]); Tel.: +92-42-9230463; Fax: +092-42-9231269
Received: 10 February 2007; in revised form: 20 February 2007 / Accepted: 21 February 2007 / Published: 22 February 2007
Full Paper: Synthesis, Characterization and Antibacterial Activity of Azomethine Derivatives Derived from 2-Formylphenoxyacetic Acid
Molecules 2007, 12, 245-254 (PDF format 91 K)

Majid M. Heravi ^1,*, Samaheh Sadjadi ¹, Hossein A. Oskooie ¹, Rahim Hekmat Shoar ¹ and Fatemeh F. Bamoharram ^2,†
1 Department of Chemistry, School of Sciences, Azzahra University, Vanak, Tehran, Iran
2 Department of Chemistry, School of Sciences, Azad University, Khorasan Branch, Mashhad, Iran
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 8 January 2007; in revised form: 10 February 2007 / Accepted: 12 February 2007 / Published: 26 February 2007
Full Paper: Heteropolyacids as Green and Reusable Catalysts for the Synthesis of 3,1,5-Benzoxadiazepines
Molecules 2007, 12, 255-262 (PDF format 73 K)
(This paper belongs to Special Issue on Heterocycles)

Antonio Fiorentino*, Brigida D’Abrosca, Severina Pacifico, Annunziata Golino, Claudio Mastellone, Palma Oriano, and Pietro Monaco
Dipartimento di Scienze della Vita, Seconda Università degli Studi di Napoli – via Vivaldi 43, I-81100 Caserta, Italy
* Author to whom correspondence should be addressed. E-mail: [email protected]
Received: 21 January 2007; in revised form: 13 February 2007 / Accepted: 27 February 2007 / Published: 28 February 2007
Full Paper: Reactive Oxygen Species Scavenging Activity of Flavone Glycosides from Melilotus neapolitana
Molecules 2007, 12, 263-270 (PDF format 79 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Felicia Megumi Ito ¹, Jacqueline Marques Petroni ¹, Dênis Pires de Lima ¹, Adilson Beatriz ^1,*, Maria Rita Marques ², Manoel Odorico de Moraes ³, Letícia Veras Costa-Lotufo ³, Raquel Carvalho Montenegro ³, Hemerson Iury Ferreira Magalhães ³ and Cláudia do Ó Pessoa ³
1 Department of Chemistry, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil. Emails: [email protected], [email protected], [email protected]
2 Department of Morphophysiology, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil. E-mail: [email protected]
3 Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil. E-mail: [email protected], [email protected], [email protected], [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]; Homepage: http://www.dqi.ufms.br/~lp4/adilson.htm.
Received: 30 January 2007; in revised form: 14 February 2007 / Accepted: 16 February 2007 / Published: 27 February 2007
Full Paper: Synthesis and Biological Evaluation of Rigid Polycyclic Derivatives of the Diels-Alder Adduct Tricyclo[6.2.1.02,7]undeca-4,9-dien-3,6-dione
Molecules 2007, 12, 271-282 (PDF format 89 K)

Issue 3 (March 2007) pages 283-702

Stanislava Maric ³, Mila Jukic ¹, Visnja Katalinic ² and Mladen Milos ^1,*
1 Department of Biochemistry, Faculty of Chemistry and Technology, University of Split, Teslina 10/V, 21000 Split, Croatia
2 Department of Nutritional Technology and Biotechnology, Faculty of Chemistry and Technology, University of Split, Teslina 10/V, 21000 Split, Croatia
3 Department of Chemistry, Faculty of Science and Education, University of Mostar, Matice hrvatske bb, 88 000 Mostar, Bosnia and Herzegovina
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 8 February 2007; in revised form: 23 February 2007 / Accepted: 23 February 2007 / Published: 2 March 2007
Full Paper: Comparison of Chemical Composition and Free Radical Scavenging Ability of Glycosidically Bound and Free Volatiles from Bosnian Pine (Pinus heldreichii Christ. var. leucodermis)
Molecules 2007, 12, 283-289 (PDF format 57 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Rafi Ullah Khan*, Siegfried Bajohr, Frank Graf and Rainer Reimert
Engler-Bunte-Institut, Bereich Gas, Erdöl und Kohle, Engler Bunte Ring 1, Universität Karlsruhe, D-76131 Karlsruhe, Germany; E-mails: [email protected], [email protected], [email protected]
* Author to whom correspondence should be addressed. E-mail: [email protected]
Received: 20 February 2007; in revised form: 1 March 2007 / Accepted: 1 March 2007 / Published: 2 March 2007
Full Paper: Modeling of Acetylene Pyrolysis under Vacuum Carburizing Conditions in a Tubular Flow Reactor^†
Molecules 2007, 12, 290-296 (PDF format 152 K)
† Paper presented at ECSOC-10, 1-30 November 2006

Jian-yu Jin ¹, Li-xue Zhang ^2,*, Xian-xing Chen ³, An-jiang Zhang ² and Hai-le Zhang ⁴
1 College of Education, Wenzhou University, Wenzhou 325035, P.R. China
2 College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325027, P.R. China
3 College of Life and Environmental Sciences, Wenzhou University, Wenzhou 325027, P.R. China
4 Department of Molecular Biology & Chemistry, Scripps Research Institute, San Diego, CA 92037, USA; E-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel: (+86) 577-88373073; Fax: (+86) 577-88339081
Received: 12 February 2007; in revised form: 27 February 2007 / Accepted: 28 February 2007 / Published: 3 March 2007
Full Paper: Syntheses and Biological Activities of 6-Aryl-3-(3-hydroxypropyl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines
Molecules 2007, 12, 297-303 (PDF format 100 K)

Hamid Golchoubian * and Farideh Hosseinpoor
Department of Chemistry, University of Mazandaran, P.O. Box 453, Babolsar, Iran
* Author to whom correspondence should be addressed. Tel/Fax: (98)-1125242002, e-mail: [email protected], [email protected]
Received: 10 January 2007; in revised form: 14 February 2007 / Accepted: 18 February 2007 / Published: 3 March 2007
Communication: Effective Oxidation of Sulfides to Sulfoxides with Hydrogen Peroxide under Transition-Metal-Free Conditions
Molecules 2007, 12, 304-311 (PDF format 39 K)

Hui Yao ^1,2, Guang-Xiong Zhou ³, Qiong Wu ², Guang-Qing Lei ², Dao-Feng Chen ¹, Jia-Kuan Chen ² and Tong-Shui Zhou ^2,*
1 Department of Pharmacognosy, School of Pharmacy, Fudan University. Yi Xue Yuan Rd. No.138, Shanghai 200032, P.R. China; E-mails: [email protected], [email protected]
2 School of Life Sciences, Fudan University. Handan Rd. No. 220, Shanghai 200433, P.R. China; Email: [email protected]
3 School of Pharmacy, Jinan University, Guangzhou 510632, P.R. China; E-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel: (+86) 21 65642206; Fax: (+86) 21 65642206
Received: 5 February 2007; in revised form: 13 February 2007 / Accepted: 18 February 2007 / Published: 6 March 2007
Communication: Mistletonone, a Novel Antioxidative Diarylheptanoid from the Branches and Leaves of Viscum coloratum
Molecules 2007, 12, 312-317 (PDF format 68 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Luis Espinoza Catalán ^1,*, Héctor Carrasco Altamirano ², Mauricio Cuellar Fritis ³, Claudio Gallardo Araya ¹ and Karen Catalán Marín ¹
1 Departamento de Química, Universidad Técnica Federico Santa María, Av. España N° 1680, Valparaíso, Chile
2 Departamento de Ciencias Químicas, Universidad Andrés Bello, Campus Viña del Mar, Los Fresnos N° 52, Viña del Mar, Chile
3 Facultad de Farmacia, Universidad de Valparaíso, Av. Gran Bretaña N° 1093, Valparaíso, Chile
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 22 November 2006; in revised form: 19 January 2007 / Accepted: 24 January 2007 / Published: 6 March 2007
Full Paper: Oxidative Degradations of the Side Chain of Unsaturated Ent-labdanes. Part I.
Molecules 2007, 12, 318-327 (PDF format 184 K)

Kolisetty Sambasiva Rao*, Goriparthi Venu Babu and Yemireddy Venkata Ramnareddy
School of Studies in Chemistry, Vikram University, Ujjain, M.P. India- 456010
* Author to whom correspondence should be addressed: E-Mail: [email protected]; Tel. (+91)-09282155564.
Received: 14 November 2005; in revised form: 20 February 2007 / Accepted: 21 February 2007 / Published: 7 March 2007
Full Paper: Acylated Flavone Glycosides from the Roots of Saussurea lappa and Their Antifungal Activity
Molecules 2007, 12, 328-344 (PDF format 180 K)

Zuhal Turgut *, Emel Pelit and Adem Köycü
Yildiz Technical University, Faculty of Art and Sciences, Department of Chemistry, Davutpasa
Campus, 34210, Istanbul, Turkey
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 15 February 2007; in revised form: 2 March 2007 / Accepted: 3 March 2006 / Published: 7 March 2006
Full Paper: Synthesis of New 1,3-Disubstituted-2,3-dihydro-1H-naphth-[1,2e][1,3]oxazines
Molecules 2007, 12, 345-352 (PDF format 81 K)

Jie Li, Dong-Lin Chen, Xi-Xian Jian and Feng-Peng Wang*
Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, No. 17, Duan 3, Renmin Nan Road, Chengdu 610041, P. R. China
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 11 January 2007; in revised form: 14 February 2007 / Accepted: 18 February 2007 / Published: 8 March 2007
Full Paper: New Diterpenoid Alkaloids from the Roots of Delphinium tiantaishanense
Molecules 2007, 12, 353-360 (PDF format 96 K)
(This paper belongs to Special Issue on Heterocycles)

Yehya M. Elkholy
Chemistry Department, Faculty of Science, Helwan University, Ain-Helwan, Cairo, Egypt; E-mail: [email protected]
Received: 24 January 2007; in revised form: 10 February 2007 / Accepted: 21 February 2007 / Published: 8 March 2007
Full Paper: An Efficient Synthesis of Pyrazolo[3,4- b]quinolin-3-amine and Benzo[b][1,8]naphthyridine Derivatives
Molecules 2007, 12, 361-372 (PDF format 160 K)

Abeer M Al-Ghananeem † and Peter A Crooks*
Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington,
Kentucky 40536, USA; † e-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 10 February 2007; in revised form: 5 March 2007 / Accepted: 5 March 2007 / Published: 8 March 2007
Review: Phase I and Phase II Ocular Metabolic Activities and the Role of Metabolism in Ophthalmic Prodrug and Codrug Design and Delivery
Molecules 2007, 12, 373-388 (PDF format 80 K)
(This paper belongs to Special Issue on Prodrugs: from Design to Applications. Guest Editor: Dr. Jean Jacques Vanden Eynde)

Topul Rali ^1,*, Stewart W. Wossa ², David N. Leach ^3,† and Peter G. Waterman ³
1 Chemistry Department, University of PNG, P.O. Box 320, University, Papua New Guinea
2 Faculty of Science, University of Goroka, P.O. Box 1078, Goroka, Papua New Guinea; E-mail: [email protected]
3 Center for Phytochemistry and Pharmacology, Southern Cross University, P.O. Box 157, Lismore, NSW 2480, Australia; † e-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 17 November 2006; in revised form: 8 February 2007 / Accepted: 12 February 2007 / Published: 9 March 2007
Communication: Volatile Chemical Constituents of Piper aduncum L and Piper gibbilimbum C. DC (Piperaceae) from Papua New Guinea
Molecules 2007, 12, 389-394 (PDF format 56 K)
(This paper was kindly edited by Dr. Peter Karuso, e-mail [email protected])

Tine Van Neck, Sarah Van Mierloo and Wim Dehaen*
Department of Chemistry, University of Leuven, Celestijnenlaan 200F B-3001 Leuven, Belgium
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel. (+32) 16 32 74 39; Fax (+32) 16 32 79 90
Received: 1 March 2007; in revised form: 8 March 2007 / Accepted: 8 March 2007 / Published: 9 March 2007
Full Paper: Functionalisation of Artemisinin and Its Ring-contracted Derivatives
Molecules 2007, 12, 395-405 (PDF format 99 K)

George A. Kraus ^1,*, Jaehoon Bae 1, Lankun Wu ² and Eve Wurtele ²
1 Iowa State University Department of Chemistry, Ames, IA 50011, USA. Tel. +1 515-294-7794; Fax: +1 515-294-0105;
2 Iowa State University Department of Genetics, Development and Cell Biology, Ames, IA 50011, USA
* Author to whom correspondence should be addressed; e-mail: [email protected]
Received: 8 February 2007; in revised form: 7 March 2007 / Accepted: 7 March 2007 / Published: 10 March 2007
Full Paper: The Synthesis and Natural Distribution of the Major Ketone Constituents in Echinacea pallida
Molecules 2007, 12, 406-414 (PDF format 150 K)

Kun Xie ¹, You-Cheng Liu ^1,2,*, Yi Cui ¹, Jian-Ge Wang³, Yao Fu ¹ and Thomas C.W. Mak ⁴
1 Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, P.R. China; E-mails: [email protected], [email protected], [email protected]
2 College of Chemistry, Lanzhou University, Lanzhou, Gansu 730000, P.R. China
3 Department of Chemistry, Luoyang Normal University, Luoyang, Henan, 471022, P.R. China; Email: [email protected]
4 Department of Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, P.R. China; E-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected],
Received: 25 February 2007; in revised form: 7 March 2007 / Accepted: 7 March 2007 / Published: 12 March 2007
Full Paper: N-Methyl-(R)-3-(tert-Butyl)-Sulfinyl-1,4-Dihydropyridine: A Novel NADH Model Compound
Molecules 2007, 12, 415-422 (PDF format 97 K, Supplementary Material, PDF format 330 KB)

Deborah H. Markowicz Bastos ^1,*, Luciane A. Saldanha ¹, Rodrigo R. Catharino ², Alexandra C.H.F. Sawaya ², Ildenize B.S. Cunha ², Patrícia O. Carvalho ³ and Marcos N. Eberlin ²
1 Nutrition Department, School of Public Health, São Paulo University, Av. Dr. Arnaldo, 715, São Paulo, SP, CEP 01246-904, fax/phone 55-11-30617705, Brazil
2 Thomson Mass Spectrometry Laboratory, Chemistry Institute, State University of Campinas, UNICAMP, Campinas, SP, Brazil; E-mails: [email protected], [email protected], [email protected], [email protected]
3 School of Pharmacy, São Francisco University, Bragança Paulista, SP, Brazil; E-mail: [email protected]
* Author to whom correspondence should be addressed; E-Mail: [email protected]; Phone: (+55)-11-30617705, Fax: (+55) 11-20617771
Received: 21 December 2006; in revised form: 3 March 2007 / Accepted: 4 March 2007 / Published: 12 March 2007
Full Paper: Phenolic Antioxidants Identified by ESI-MS from Yerba Maté (Ilex paraguariensis) and Green Tea (Camelia sinensis) Extracts
Molecules 2007, 12, 423-432 (PDF format 160 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Saeed Dehghanpour *, Majid M. Heravi * and Fatemeh Derikvand
Department of Chemistry, School of Sciences, Azzahra University, Vanak, Tehran, Iran
* Authors to whom correspondence should be addressed. E-mails: [email protected]; [email protected]
Received: 7 January 2007; in revised form: 6 February 2007 / Accepted: 10 February 2007 / Published: 12 March 2007
Full Paper: N,N'-Ethylene-bis(benzoylacetoniminato) Copper (II), Cu(C₂₂H₂₂N₂O₂), a New Reagent for Aromatization of Hantzsch 1,4-Dihydropyridines
Molecules 2007, 12, 433-438 (PDF format 54 K)

Fatima-Zohra Zradni ^1,*, Jack Hamelin ² and Aicha Derdour ^1,†
1 Faculté des Sciences, Département de Chimie, Université d’Es-sénia, Oran, B.P 1524, Algeria; ^†E-Mail: [email protected]
2 Groupe d'Ingénierie Chimique et Molécules pour le Vivant 3(ICMV3)-UMR 6226, Université de Rennes 1, Campus de Beaulieu, 35042 Rennes, France; E-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel/Fax: (+213) 41 58 70 57
Received: 27 January 2007; in revised form: 17 February 2007 / Accepted: 7 March 2007 / Published: 12 March 2007
Full Paper: Solventless Lactam Synthesis by Intramolecular Cyclizations of α-Iminoester Derivatives under Microwave Irradiation
Molecules 2007, 12, 439-454 (PDF format 156 K)

Pablo Anselmo García ¹, Alaíde Braga de Oliveira ² and Ronan Batista ^3,*
1 Departamento de Química Farmacéutica, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, 37007 Salamanca, Spain; E-mail: [email protected]
2 Departamento de Produtos Farmacêuticos, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, 31270-901 Belo Horizonte – MG, Brazil; E-mail: [email protected]
3 Departamento de Estudos Básicos e Instrumentais, Universidade Estadual do Sudoeste da Bahia, BR 415, Km 03, s/nº, 45.700-000 Itapetinga – BA, Brazil
* Author to whom correspondence should be addressed; E-mail: [email protected].
Received: 18 February 2007; in revised form: 12 March 2007 / Accepted: 12 March 2007 / Published: 13 March 2007
Review: Occurrence, Biological Activities and Synthesis of Kaurane Diterpenes and their Glycosides
Molecules 2007, 12, 455-483 (PDF format 172 K)

Nihal Turkmen, Y. Sedat Velioglu *, Ferda Sari and Gokce Polat
Ankara University, Faculty of Engineering, Department of Food Engineering, 06110-Diskapi-Ankara, Turkey; E-mails: [email protected] (Nihal Turkmen); [email protected] (Ferda Sari); [email protected] (Gokce Polat).
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 8 January 2007; in revised form: 6 March 2007 / Accepted: 12 March 2007 / Published: 13 March 2007
Full Paper: Effect of Extraction Conditions on Measured Total Polyphenol Contents and Antioxidant and Antibacterial Activities of Black Tea
Molecules 2007, 12, 484-496 (PDF format 84 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Mohammed H. Al-Huniti ¹, Mustafa M. El-Abadelah ¹, Jalal A. Zahra ^1,*, Salim S. Sabri ² and Arnd Ingendoh ³
1 Chemistry Department, Faculty of Science, The University of Jordan, Amman 11942, Jordan; Emails: [email protected], [email protected]
2 University of Sharjah, Sharjah, P. O. Box 27272, United Arab Emirates (UAE); E-mail: [email protected]
3 Bruker Daltonik GmbH, Fahrenheitstr. 4, D-28359 Bremen, Germany; E-mail: [email protected]
*Author to whom correspondence should be addressed; E-mail: [email protected]; Fax: +962-6 5348932; Tel.: +962-6 5355000 (ext. 22163)
Received: 8 March 2007; in revised form: 14 March 2007 / Accepted: 15 March 2007 / Published: 15 March 2007
Full Paper: Facile Synthesis of Some Novel Pyrido[3', 2': 4, 5]thieno[2,3-b][1,4]thiazine-8-carboxylic Acids
Molecules 2007, 12, 497-503 (PDF format 68 K)

Dinesh Ramesh Garud ¹, Mamoru Koketsu ^2,* and Hideharu Ishihara ^1,*
1 Department of Chemistry, Faculty of Engineering, Gifu University, Gifu 501-1193, Japan
2 Division of Instrumental Analysis, Life Science Research Center, Gifu University, Gifu 501-1193, Japan
* Authors to whom correspondence should be addressed; E-mails: [email protected]; [email protected]
Received: 5 March 2007; in revised form: 15 March 2007 / Accepted; 15 March 2007 / Published: 17 March 2007
Review: Isoselenocyanates: A Powerful Tool for the Synthesis of Selenium-Containing Heterocycles
Molecules 2007, 12, 504-535 (PDF format 260 K)
(This paper belongs to Special Issue on Heterocycles)

Yun-Song Wang ¹, Jing-Hua Yang ^1,*, Shi-De Luo ², Hong-Bin Zhang ¹ and Liang Li ^1,*
1 Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, P.R. China; E-mails: [email protected] (Yun-Song Wang), [email protected] (Hong-Bin Zhang)
2 Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P.R. China; E-mail: [email protected] (Shi-De Luo)
* Authors to whom correspondence may be addressed; E-mail: [email protected] (Liang Li), [email protected] (Jing-Hua Yang); Tel: 86-871-5031119/Fax: 86-871-5035538
Received: 20 December 2006; in revised form: 11 February 2007 / Accepted: 17 February 2007 / Published: 17 March 2007
Communication: New Cytotoxic Steroid from Stachyurus himalaicus var. himalaicus
Molecules 2007, 12, 536-542 (PDF format 74 K)

Guirong Qu *, Zhiguang Zhang, Haiming Guo, Mingwei Geng and Ran Xia
College of Chemistry and Environmental Science, Henan Normal University, Xinxiang 453007, P.R. China; E-mails: [email protected]; [email protected]; [email protected];
[email protected]
* Author to whom correspondence should be addressed. E-mail: [email protected], [email protected], [email protected]
Received: 13 December 2006; in revised form: 11 February 2007 / Accepted: 17 February 2007 / Published: 19 March 2007
Full Paper: Microwave-promoted Facile and Efficient Preparation of N-(alkoxycarbonylmethyl) Nucleobases − Building Blocks for Peptide Nucleic Acids
Molecules 2007, 12, 543-551 (PDF format 76 K)

Huaqiang Dong ^1,2,*, Zhengxiang Ning ¹, Lijing Yu ¹, Lin Li ¹, Lichao Lin ² and Jianbo Huang ²
1 College of Light Industry and Food Technology, South China University of Technology, Guangzhou, 510641, P.R. China; E-mails: [email protected]; [email protected]; [email protected]
2 Department of Food Science, Foshan University, Nanhai Dali, Guangdong 528231, P.R. China; E-mails: [email protected]; [email protected]
* Author to whom correspondence should be addressed; E.mail: [email protected]; Tel: (+86)-757-85505064
Received: 6 February 2007; in revised form: 13 March 2007 / Accepted: 13 March 2007 / Published: 20 March 2007
Communication: Preparative Separation and Identification of the Flavonoid Phlorhizin from the Crude Extract of Lithocarpus Polystachyus Rehd
Molecules 2007, 12, 552-562 (PDF format 100 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Helmut Rosemeyer ^1,*, Martina Anders ¹ and Frank Seela ^1,2
1 Organische Chemie I – Bioorganische Chemie, Institut für Chemie, Fachbereich Biologie/Chemie, Universität Osnabrück, Barbarastr. 7, D-49069 Osnabrück, Germany
2 Laboratory of Bioorganic Chemistry and Chemical Biology, Center for Nanotechnology, Heisenbergstr. 11, D-48149 Münster, Germany
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 9 March 2007; in revised form: 19 March 2007 / Accepted: 19 March 2007 / Published: 21 March 2007
Full Paper: Symmetrically and Unsymmetrically Bridged Methylenebis(allopurinols): Synthesis of Dimeric Potential Anti-Gout Drugs
Molecules 2007, 12, 563-575 (PDF format 199 K)
(This paper was originally submitted to International Journal of Molecular Sciences and processed by Dr. Angelika Kren)

Djordje Malenčić ^1,*, Milan Popović ¹ and Jegor Miladinović ²
1 Faculty of Agriculture, University of Novi Sad, Trg Dositeja Obradovića 8, 21000 Novi Sad, Serbia; e-mail: [email protected]
2 Institute of Field and Vegetable Crops, Maksima Gorkog 30, 21000 Novi Sad, Serbia; e-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 13 February 2007; in revised form: 6 March 2007 / Accepted: 14 March 2007 / Published: 21 March 2007
Full Paper: Phenolic Content and Antioxidant Properties of Soybean (Glycine max (L.) Merr.) Seeds
Molecules 2007, 12, 576-581 (PDF format 60 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Xinping Huang ^1,2, Min Li ^1,*, Bo Xu ¹, Xiaobin Zhu ², Zhiwei Deng ³ and Wenhan Lin ^1,*
1 State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100083, P.R. China, Tel: (+86) 10-82806188; Fax: (+86) 10-82802724
2 Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, P.R. China
3 Analytic and Testing Center, Beijing Normal University, Beijing 100073, P.R. China
* Authors to whom correspondence may be addressed; E-mails: [email protected]; [email protected]
Received: 18 February 2007; in revised form: 18 March 2007 / Accepted: 21 March 2007 / Published: 21 March 2007
Full Paper: Proteasome and NF-κB Inhibiting Phaeophytins from the Green Alga Cladophora fascicularis
Molecules 2007, 12, 582-592 (PDF format 202 K)

Dimitrios Tsimogiannis ^1,*, Martina Samiotaki ², George Panayotou ² and Vassiliki Oreopoulou ^1,*
1 National Technical University of Athens, School of Chemical Engineering, 9 Iroon Polytehniou st, Zografou Campus, 157 80, Athens, Greece; Tel: +302107723166, Fax: +302107723163.
2 Biomedical Sciences Research Center “Alexander Fleming”, 34 Fleming st, 16672, Vari, Greece
* Authors to whom correspondence should be addressed; E-mail: [email protected]; [email protected]
Received: 15 January 2007; in revised form: 13 March 2007 / Accepted: 14 March 2007 / Published: 21 March 2007
Full Paper: Characterization of Flavonoid Subgroups and Hydroxy Substitution by HPLC-MS/MS
Molecules 2007, 12, 593-606 (PDF format 96 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Mohammad Babar Ali ¹, Eun-Joo Hahn ² and Kee-Yoeup Paek ²^,*
1 Metabolic Regulation Laboratory, Food Biotechnology Division, National Food Research Institute, Kannondai, Tsukuba, Ibaraki-305-8642, Japan; E-mail: [email protected] or [email protected]; Phone: (+81)-29-838-8050; Fax: (+81)-29-838-8122
2 Research Center for the Development of Advanced Horticultural Technology, Chungbuk National University, Cheong-ju, 361-763, Republic of Korea; Phone: (+82)-43-261-3245; Fax: (+82)-43-272-5369; E-mails: [email protected], [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 24 January 2007; in revised form: 13 March 2007 / Accepted: 18 March 2007 / Published: 23 March 2007
Full Paper: Methyl Jasmonate and Salicylic Acid Induced Oxidative Stress and Accumulation of Phenolics in Panax ginseng Bioreactor Root Suspension Cultures
Molecules 2007, 12, 607-621 (PDF format 124 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Mona A. Mahran ^1,*, Samia William ², Fatem Ramzy ² and Amira M. Sembel ³
1 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, Alexandria, Egypt
2 Theodor Bilharz Research Institute, Ministry of Scientific Research, Warak El Hadar, Embaba, Cairo, Egypt
3 Department of Pharmacology, Faculty of Pharmacy, University of Alexandria, Alexandria, Egypt
† Part of this work was presented as a poster (No. 37) at the 2nd Mediterranean Organic Chemistry Meeting, Almeria, Spain, March 2003.
* Author to whom correspondence should be addressed; e-mail: [email protected]
Received: 9 November 2006; in revised form: 21 March 2007 / Accepted: 23 March 2007 / Published: 26 March 2007
Full Paper: Synthesis and in vitro Evaluation of New Benzothiazole Derivatives as Schistosomicidal Agents†
Molecules 2007, 12, 622-633 (PDF format 74 K)

Alexander Mehner ¹, Ana L. Montero ², Ricardo Martinez ² and Stefan Spange ^1,*
1 Department of Polymer Chemistry, Institute of Chemistry, Chemnitz University of Technology, Strasse der Nationen 62, D-09111 Chemnitz, Germany
2 University of Havana, Polymer Laboratory, Zapata y G, Havana 10400, Cuba
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 8 March 2007; in revised form: 23 March 2007 / Accepted: 23 March 2007 / Published: 26 March 2007
Full Paper: Synthesis of 5-Acetoxymethyl- and 5-Hydroxymethyl-2-vinylfuran
Molecules 2007, 12, 634-640 (PDF format 60 K)
(This paper belongs to Special Issue on Heterocycles)

Christian Cervino ^1,*, Dietmar Knopp ^1,†, Michael. G. Weller ² and Reinhard Niessner ¹
1 Institute of Hydrochemistry, Chair for Analytical Chemistry, Technische Universität München, Marchioninistrasse 17, 81377 München, Germany; † E-mail: [email protected]
2 Federal Institute for Materials Research and Testing (BAM), Division I.5 (Bioanalytics), Richard-Willstätter-Strasse 11, 12489 Berlin, Germany; E-mail: [email protected]
* Author to whom correspondence should be addressed. E-mail: [email protected]
Received: 14 March 2007; in revised form: 25 March 2007 / Accepted: 26 March 2007 / Published: 27 March 2007
Full Paper: Novel Aflatoxin Derivatives and Protein Conjugates
Molecules 2007, 12, 641-653 (PDF format 143 K; Supplementary Material, 10 pages, PDF format 515 KB)

Igor G. Zenkevich ^1,*, Anna Yu. Eshchenko ², Svetlana V. Makarova ², Alexander G. Vitenberg ¹, Yuri G. Dobryakov ¹ and Viktor A. Utsal ³
1 St. Petersburg State University, Research Institute of Chemistry, Universitetsky pr., 26, St. Petersburg 198504, Russia; E-mails: [email protected]; [email protected]
2 Interregional Center “Adaptogen”, Piskarevsky pr., 47/5, St. Petersburg 195067, Russia; E-mails: [email protected]; [email protected]
3 Russian Scientific Center “Applied Chemistry”, St. Petersburg 197198, Dobrolubov ave., 14, Russia; E-mail: [email protected]
* Author to whom correspondence should be addressed; E-mails: [email protected]; [email protected]
Received: 13 January 2007; in revised form: 22 March 2007 / Accepted: 25 March 2007 / Published: 27 March 2007
Full Paper: Identification of the Products of Oxidation of Quercetin by Air Oxygen at Ambient Temperature
Molecules 2007, 12, 654-672 (PDF format 223 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Ming Dong Li ^†, You Guang Zheng and Min Ji *
Institute of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering, Jiangsu
Laboratory for Biomaterials and Devices, Southeast University, 210096 Nanjing, P. R. China; † E-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel.: (+86) 25-83272078
Received: 9 March 2007; in revised form: 22 March 2007 / Accepted: 23 March 2007 / Published: 28 March 2007
Full Paper: Synthesis of Gefitinib from Methyl 3-Hydroxy-4-methoxy-benzoate
Molecules 2007, 12, 673-678 (PDF format 55 K)
(This paper has been withdrawn. Editorial Note: Withdrawn Paper: Li, M. D.; Zheng, Y. G.; Ji, M. Synthesis of Gefitinib from Methyl 3-Hydroxy-4-methoxybenzoate. Molecules 2007, 12, 673-678. Molecules 2007, 12, 2160)

Jianping Sun ^{1, 2}, Feng Liang ³, Yan Bin ², Ping Li ³ and Changqing Duan ^1,*
1 Center for Viticulture and Enology, College of Food Science & Nutritional Engineering, China Agriculture University, 10083 Beijing, People’s Republic of China
2 Cofco Wines & Spirits, Co. Ltd, 100005 Beijing, People’s Republic of China
3 Agilent Technologies Co. Ltd, 100022 Beijing, People’s Republic of China
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel: (+86)-10-62737136; Fax: (+86)-10-62737136;
Received: 13 December 2006; in revised form: 24 March 2007 / Accepted: 29 March 2007/ Published: 30 March 2007
Full Paper: Screening Non-colored Phenolics in Red Wines using Liquid Chromatography/Ultraviolet and Mass Spectrometry/Mass Spectrometry Libraries
Molecules 2007, 12, 679-693 (PDF format 142 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Morteza Montazerozohori*, Shiva Joohari, Bahador Karami and Nasrin Haghighat
Department of Chemistry, Yasouj University, Yasouj 75918-74831, P. O. Box-35, Iran
* Author to whom correspondence should be addressed; E-mail: [email protected]; [email protected]
Received: 22 January 2007; in revised form: 13 February 2007 / Accepted: 26 February 2007 / Published: 31 March 2007
Full Paper: Fast and Highly Efficient Solid State Oxidation of Thiols
Molecules 2007, 12, 694-702 (PDF format 72 K)

Issue 4 (April 2007) pages 703-931

Patchreenart Saparpakorn ^1,2, Jae Hyoun Kim ³ and Supa Hannongbua ^1,2,*
1 Department of Chemistry, Faculty of Science, Kasetsart University, Chatuchak, Bangkok, 10900, Thailand; E-mail: [email protected]
2 The Center of Nanoscience KU, Kasetsart University, Bangkok 10900, Thailand
3 Department of Health Science, School of Natural Science, Dongduk Women’s University, Sungbuk-gu, Seoul, 136-714, Korea; E-mail: [email protected]
* Author to whom correspondence should be addressed. E-mail: [email protected]
Received: 26 February 2007; in revised form: 22 March 2007 / Accepted: 23 March 2007 / Published: 5 April 2007
Full Paper: Investigation on the Binding of Polycyclic Aromatic Hydrocarbons with Soil Organic Matter: A Theoretical Approach
Molecules 2007, 12, 703-715 (PDF format 477 K)
(This paper belongs to Special Issue on Heterocycles)

Li-Bin Lu, Yun-Qian Zhang, Qian-Jiang Zhu *, Sai-Feng Xue and Zhu Tao
Institute of Applied Chemistry, Guizhou University, Guiyang, 550025, People’s Republic of China
* Author to whom correspondence should be addressed; e-mail: [email protected]; Tel. (+86) 851 362 3903; Fax (+86) 851 362 0906
Received: 25 February 2007; in revised form: 19 March 2007 / Accepted: 19 March 2007 / Published: 5 April 2007
Full Paper: Synthesis and X-ray Structure of the Inclusion Complex of Dodecamethylcucurbit[6]uril with 1,4-Dihydroxybenzene
Molecules 2007, 12, 716-722 (PDF format 147 K)

Martin Matschke and Rainer Beckert*
Institute of Organic and Makromolecular Chemistry, Friedrich-Schiller University D-07743 Jena, Humboldtstr. 10, Germany
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel.: (+049) 3641 948 230; Fax: (+049) 3641 948 212
Received: 22 March 2007; in revised form: 29 March 2007 / Accepted: 29 March 2007 / Published: 5 April 2007
Full Paper: Multi-step Redox Systems with NIR-Fluorescence Based on 4H-Imidazoles
Molecules 2007, 12, 723-734 (PDF format 130 K)

Evangelia N. Tzanetou ¹, Konstantinos M. Kasiotis ¹, Prokopios Magiatis ² and Serkos A. Haroutounian ^1,*
1 Chemistry Laboratory, Agricultural University of Athens, Iera odos 75, Athens 11855, Greece
2 Faculty of Pharmacy, Laboratory of Pharmacognosy and Natural Products Chemistry, University of Athens, Panepistimiopolis Zografou, Athens 15771, Greece
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 13 March 2007; in revised form: 25 March 2007 / Accepted: 27 March 2007 / Published: 10 April 2007
Full Paper: Synthesis of (R)-Dihydropyridones as Key Intermediates for an Efficient Access to Piperidine Alkaloids
Molecules 2007, 12, 735-744 (PDF format 99 K)

Jiangrong Li ¹ and Yueming Jiang ^1,2,*
1 College of Food Science, Biotechnology and Environmental Engineering, Zhejiang Gongshang University, Hangzhou, 310035, The People’s Republic of China; e-mail: [email protected]
2 South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, The People’s Republic of China
* Author to whom correspondence should be addressed; E-mail: [email protected].
Received: 14 March 2007; in revised form: 26 March 2007 / Accepted: 28 March 2007 / Published: 11 April 2007
Review: Litchi Flavonoids: Isolation, Identification and Biological Activity
Molecules 2007, 12, 745-758 (PDF format 106 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Xuewu Duan ¹, Genfu Wu ² and Yueming Jiang ^1,*
1 South China Botanical Garden, The Chinese Academy of Sciences, Guangzhou Leyiju 510650; P. R. China; E-mail: [email protected]
2 College of Life Sciences, Zhejiang University, Hangzhou 310012; P. R. China; E-mail: [email protected]
* Author to whom correspondence should be addressed: Email: [email protected]; Tel.: (+86) 20 37252525; Fax: (+86) 20 37252831
Received: 14 March 2007; in revised form: 25 March 2007 / Accepted: 30 March 2007 / Published: 11 April 2007
Full Paper: Evaluation of the Antioxidant Properties of Litchi Fruit Phenolics in Relation to Pericarp Browning Prevention
Molecules 2007, 12, 759-771 (PDF format 98 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Christos Liolios ¹, Hocine Laouer ², Nacira Boulaacheb ², Olga Gortzi ³ and Ioanna Chinou ^1,*
1 Department of Pharmacy, Div. of Pharmacognosy, Chemistry of Natural Products, University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece; E-mail: [email protected];
Fax: (+30) 2107274115.
2 Department of Biology, Faculty of Sciences, University Ferhat Abbas, Setif, Algeria; E-mails: [email protected]; [email protected]; Fax: (+213) 36 92 51 22
3 Department of Food Technology, Technological Educational Institution (T.E.I.) of Larissa, Terma Temponera str., Karditsa, Greece; E-mail: [email protected]; Fax: (+30) 2441072070
* Author to whom correspondence should be addressed; e-mail: [email protected], Fax: (+30) 2107274115
Received: 27 February 2007; in revised form: 27 March 2007 / Accepted: 3 April 2007 / Published: 12 April 2007
Full Paper: Chemical Composition and Antimicrobial Activity of the Essential Oil of Algerian Phlomis bovei De Noé subsp. bovei
Molecules 2007, 12, 772-781 (PDF format 107 K)

Tudor Rosu ^1,*, Aurelian Gulea ², Anca Nicolae ³ and Rodica Georgescu ⁴
1 Inorganic Chemistry Department, University of Bucharest, 23 Dumbrava Rosie Street, sector 2, Bucharest, Romania
2 Faculty of Chemistry, Inorganic Chemistry Department, USM-R. Moldavia; E-mail: [email protected]
3 Organic Chemistry Department, University of Bucharest, 90 – 92 Panduri Bd., sector 4, Bucharest, Romania; E-mail: [email protected]
4 Nuclear Physics and Engineering Institute “Horia Hulubei”, Bucharest, Romania; E-mail: [email protected]
* Author to whom correspondence should be addressed; E-mails: [email protected] or [email protected]
Received: 27 February 2007; in revised form: 5 April 2007 / Accepted: 12 April 2007 / Published: 17 April 2007
Full Paper: Complexes of 3dⁿ Metal Ions with Thiosemicarbazones: Synthesis and Antimicrobial Activity
Molecules 2007, 12, 782-796 (PDF format 205 K, Supplementary information for available samples, PDF format 128 KB)

Christophe Curti, Armand Gellis and Patrice Vanelle*
Laboratoire de Chimie Organique Pharmaceutique, UMR CNRS 6517, Université de la Méditerranée, Faculté de Pharmacie, 27, boulevard Jean Moulin, 13385 Marseille Cedex 05, France
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 13 February 2007; in revised form: 14 April 2007 / Accepted: 16 April 2007 / Published: 18 April 2007
Full Paper: Synthesis of α,β-Unsaturated Ketones as Chalcone Analogues via a S_RN1 Mechanism
Molecules 2007, 12, 797-804 (PDF format 66 K)

Francesco Puoci ^1,*, Francesca Iemma ¹, Giuseppe Cirillo ¹, Nevio Picci ¹, Pietro Matricardi ² and Franco Alhaique ²
1 Dipartimento di Scienze Farmaceutiche, Università della Calabria, Edificio Polifunzionale, Arcavacata di Rende (CS) 87036, Italy
2 Dipartimento di Studi di Chimica e Tecnologia delle Sostanze Biologicamente Attive, University “La Sapienza”, P.le A. Moro 5, 00185 Roma, Italy
* Author to whom correspondence should be addressed; email: [email protected]; Tel. (+39) 0984493151, fax (+39) 0984493151
Received: 21 March 2007; in revised form: 13 March 2007 / Accepted: 16 April 2007 / Published: 18 April 2007
Full Paper: Molecularly Imprinted Polymers for 5-Fluorouracil Release in Biological Fluids
Molecules 2007, 12, 805-814 (PDF format 69 K)

Il Hong Son, Sung Ik Lee, Hyun Duk Yang and Hyung-In Moon*
Department of Neuroscience and Inam Neuro Science Research Center, Sanbon Medical Center, Wonkwang University, Gunpo-city, Kyunggido, 435-040, South Korea
* To whom correspondence should be addressed; [email protected]; Fax. (+82)-313902414
Received: 5 April 2007; in revised form: 16 April 2007 / Accepted: 16 April 2007 / Published: 20 April 2007
Communication: Bis(4-hydroxybenzyl)sulfide: a Sulfur Compound Inhibitor of Histone Deacetylase Isolated from Root Extract of Pleuropterus ciliinervis
Molecules 2007, 12, 815-820 (PDF format 44 K)

Gene-Hsiang Lee ^1,2 and Hsin-Ta Wang ^1,*
1 Institute of Organic and Polymeric Materials, National Taipei University of Technology, Taipei 106, Taiwan
2 Instrumentation Center, National Taiwan University, Taipei 106, Taiwan
* Author to whom correspondence should be addressed; [email protected]
Received: 25 March 2007; in revised form: 18 April 2007 / Accepted: 19 April 2007 / Published: 23 April 2007
Full Paper: Different Supramolecular Coordination Polymers of [N,N'-di(pyrazin-2-yl)-pyridine-2,6-diamine]Ni(II) with Anions and Solvent Molecules as a Result of Hydrogen Bonding
Molecules 2007, 12, 821-831 (PDF format 382 K)

Lin Zhang, Zhen-Huan Liu and Jing-Kui Tian*
Institute of Modern Chinese Medicine, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, P. R. China; Tel: (+86)-571-88208454; Fax: (+86)-571-88208446; E-mail: [email protected] (Zhang)
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 30 January 2007; in revised form: 2 April 2007 / Accepted: 3 April 2007 / Published: 23 April 2007
Full Paper: Cytotoxic Triterpenoid Saponins from the Roots of Platycodon grandiflorum
Molecules 2007, 12, 832-841 (PDF format 103 K)

Yanli You ^1,3, Xuewu Duan ¹, Xiaoyi Wei ¹, Xinguo Su ¹, Mouming Zhao ², Jian Sun ^1,3, Neungnapa Ruenroengklin ^1,3 and Yueming Jiang ^1,*
1 South China Botanical Garden, The Chinese Academy of Sciences, Guangzhou Leyiju 510650; P. R. China; E-mail: [email protected]
2 College of Light Industry and Food Science, South China University of Technology, Guangzhou 510640; P. R. China; E-mail: [email protected]
3 Graduate School, Chinese Academy of Sciences, Beijing 100039; P. R. China
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel.: (+86) 20 37252525; Fax: (+86) 20 37252831
Received: 7 April 2007; in revised form: 20 April 2007 / Accepted: 23 April 2007 / Published: 25 April 2007
Full Paper: Identification of Major Phenolic Compounds of Chinese Water Chestnut and their Antioxidant Activity
Molecules 2007, 12, 842-852 (PDF format 138 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Bilkish Rahman, Hiroki Akutsu, Jun-ichi Yamada and Shin’ichi Nakatsuji *
Graduate School of Material Science, University of Hyogo, 3-2-1 Kouto, Kamigori, Hyogo 678-1297, Japan
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 7 April 2007; in revised form: 17 April 2007 / Accepted: 18 April 2007 / Published: 27 April 2007
Full Paper: Molecular Complexes Based on Tetrathiafulvalene and Dialkylviologens
Molecules 2007, 12, 853-860 (PDF format 232 K)

Hui Xu * and Yang Chen ^†
College of Science, Northwest A&F University, Yangling 712100, P.R. China; † E-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 28 March 2007; in revised form: 19 April 2007 / Accepted: 20 April 2007 / Published: 30 April 2007
Communication: C(aryl)-O Bond Formation from Aryl Methanesulfonates via Consecutive Deprotection and S_NAr Reactions with Aryl Halides in an Ionic Liquid
Molecules 2007, 12, 861-867 (PDF format 71 K)

Weerachai Phutdhawong ^1,*, Rungthip Kawaree ^1,2, Samart Sanjaiya ¹, Waya Sengpracha ³ and Duang Buddhasukh ⁴
1 Department of Chemistry, Faculty of Science, Maejo University, Sansai, Chiang Mai 50290, Thailand
2 Pharmaceutical Sciences Department, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50202, Thailand
3 Department of Chemistry, Faculty of Science, Silpakorn University, Nakhonpathom 73000, Thailand
4 Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai 50202, Thailand
* Author to whom correspondence should be addressed; E-mail: [email protected] or [email protected]; Tel: +6653873651, Fax: +6653869410
Received: 22 February 2007; in revised form: 27 April 2007 / Accepted: 27 April 2007 / Published: 30 April 2007
Full Paper: Microwave-Assisted Isolation of Essential oil of Cinnamomum iners Reinw. ex Bl.: Comparison with Conventional Hydrodistillation
Molecules 2007, 12, 868-877 (PDF format 94 K)

Da-Peng Yang, Hong-Fang Ji , Guang-Yan Tang , Wei Ren and Hong-Yu Zhang *
Shandong Provincial Research Center for Bioinformatic Engineering and Technique, Center for Advanced Study, Shandong University of Technology, Zibo 255049, P. R. China
* Author to whom correspondence should be addressed; E-mail: [email protected].
Received: 27 March 2007; in revised form: 23 April 2007 / Accepted: 25 April 2007 / Published: 30 April 2007
Communication: How Many Drugs Are Catecholics
Molecules 2007, 12, 878-884 (PDF format 59 K, Supplementary Material, PDF format 102 KB)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Shao-Jie Wang ^1,*, Ju-Fang Yan ², Dong Hao ¹, Xin-Wen Niu ¹ and Mao-Sheng Cheng ¹
1 Key Laboratory of New Drugs Design and Discovery of Liaoning Province, Shenyang Pharmaceutical University, Shenyang 110016, P.R. China
2 Drug Screening Center, Di Ao Pharmaceutical Group, Chengdu 123388, P.R. China
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel: (+86)24-23986421; Fax: (+86)24-23986421
Received: 21 March 2007; in revised form: 23 April 2007 / Accepted: 23 April 2007 / Published: 30 April 2007
Full Paper: Synthesis and Activity of a New Series of (Z)-3-Phenyl-2-benzoylpropenoic Acid Derivatives as Aldose Reductase Inhibitors
Molecules 2007, 12, 885-895 (PDF format 143 K)

Fátima de Campos-Buzzi ^1,2, Pâmela Padaratz ¹, Aleandra Vergilina Meira ¹, Rogério Corrêa ¹, Ricardo José Nunes ² and Valdir Cechinel-Filho ^1,*
1 Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)/CCS, Universidade do Vale do Itajaí (UNIVALI), Itajaí-SC, Brazil
2 Departamento de Química, Universidade Federal de Santa Catarina (UFSC), Florianópolis-SC, Brazil
* Author to whom correspondence should be addressed; e-mail: [email protected]; Phone: (+55) 47 3341 7525; Fax: (+55) 47 3341 7601
Received: 22 March 2007; in revised form: 22 April 2007 / Accepted: 24 April 2007 / Published: 30 April 2007
Full Paper: 4'-Acetamidochalcone Derivatives as Potential Antinociceptive Agents
Molecules 2007, 12, 896-906 (PDF format 59 K)

Qian Li ¹, Zhi-Hong Yao ², Yan-Hong Shi ³, Xin Liu ¹, Xin-Sheng Yao ² and Wen-Cai Ye ^1,2,*
1 Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009, P. R. China; E-mails: [email protected]; [email protected]
2 Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, P. R. China; E-mails: [email protected]; [email protected]
3 Department of Analytical Chemistry, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, CAS, Shanghai 201203, P. R. China; E-mail: [email protected]
* Author to whom correspondence should be addressed. E-mail: [email protected]; Fax: +86-20-85221559
Received: 23 March 2007; in revised form: 5 April 2007 / Accepted: 18 April 2007 / Published: 30 April 2007
Full Paper: Determination of the Three-dimensional Structure of Gynoside A in Solution using NMR and Molecular Modeling
Molecules 2007, 12, 907-916 (PDF format 254 K)

Tsai-Hua Kao and Bing-Huei Chen*
Department of Nutrition and Food Sciences, Fu Jen University, Taipei 242, Taiwan
* Author to whom correspondence should be addressed; E-mail: [email protected]; Phone: 886-2-29053626; Fax: 886-2-29021215
Received: 2 April 2007; in revised form: 24 April 2007 / Accepted: 25 April 2007 / Published: 30 April 2007
Full Paper: Effects of Different Carriers on the Production of Isoflavone Powder from Soybean Cake
Molecules 2007, 12, 917-931 (PDF format 134 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Issue 5 (May 2007) pages 932-1201

Olga Gortzi ¹, Stavros Lalas ^1,*, Ioanna Chinou ² and John Tsaknis ³
1 Department of Food Technology, Technological Educational Institution (T.E.I.) of Larissa, (Karditsa Annex), Terma N. Temponera str., GR-43100, Karditsa, Greece; E-mail: [email protected]
2 Department of Pharmacy, Division of Pharmacognosy, Chemistry of Natural products, University of Athens, Panepistimiopolis Zografou, GR-15771, Athens, Greece; E-mail: [email protected]
3 Department of Food Technology, Technological Educational Institution (T.E.I.) of Athens, Ag. Spyridonos str., GR-12210, Egaleo, Athens, Greece; E-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel.: (+30)-24410-76454, Fax.: (+30)-24410-41080
Received: 22 March 2007; in revised form: 25 April 2007 / Accepted: 1 May 2007 / Published: 2 May 2006
Full Paper: Evaluation of the Antimicrobial and Antioxidant Activities of Origanum dictamnus Extracts before and after Encapsulation in Liposomes
Molecules 2007, 12, 932-945 (PDF format 103 K)

Lei Chen ^1,2 and Hong-Yu Zhang ^2,*
1 College of Life Sciences, Shandong Normal University, Jinan 250014, P. R. China
2 Shandong Provincial Research Center for Bioinformatic Engineering and Technique, Center for Advanced Study, Shandong University of Technology, Zibo 255049, P. R. China
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 15 March 2007; in revised form: 30 April 2007 / Accepted: 1 May 2007 / Published: 3 May 2007
Review: Cancer Preventive Mechanisms of the Green Tea Polyphenol (-)-Epigallocatechin-3-gallate
Molecules 2007, 12, 946-957 (PDF format 187 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Karim Asadolah *, Majid M. Heravi *, Rahim Hekmatshoar and Soma Majedi
Department of Chemistry, School of Sciences, Azzahra University, Vanak, Tehran, Iran
* Authors to whom correspondence should be addressed; E-mails: [email protected] (Karim Asadolah); [email protected] (Majid M. Heravi)
Received: 15 February 2007; in revised form: 19 March 2007 / Accepted: 23 March 2007 / Published: 5 May 2007
Communication: Bis(trimethylsilyl)chromate Catalyzed Oxidations of Alcohols to Aldehydes and Ketones with Periodic Acid
Molecules 2007, 12, 958-964 (PDF format 62 K)

Yin-Pu Lv, Xian-You Wang, Bao-An Song*, Song Yang, Kai Yan, Guang-Fang Xu, Pinaki S Bhadury, Fang Liu, Lin-Hong Jin and De-Yu Hu
Center for Research and Development of Fine Chemicals, Guizhou University, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guiyang, 550025, P. R. China
* Author to whom correspondence should be addressed; E-mail: [email protected], Tel.: (+86) 851 3620521, Fax: (+86) 851 3622211
Received: 2 March 2007; in revised form 25 April 2007 / Accepted: 25 April 2007 / Published: 9 May 2007
Full Paper: Synthesis, Antiviral and Antifungal Bioactivity of 2-Cyano-acrylate Derivatives Containing Phosphonyl Moieties
Molecules 2007, 12, 965-978 (PDF format 171 K)

Jia Zhao ¹, Nai-Xing Wang ^1,2,*, Wu-Wei Wang ¹, Gui-Xia Wang ¹, Yan-Hong Liu ¹, Li Li ¹, Jin-Lan Yu ² and Xin-Liang Tang ²
1 Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100080,
P.R. China; E-mails: [email protected], [email protected], [email protected], [email protected], [email protected]
2 Beijing Insititute of Technology, Beijing 100081, P. R. China; E-mail: [email protected], [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 23 March 2007; in revised form: 17 April 2007 / Accepted: 19 April 2007 / Published: 11 May 2007
Communication: A New Type of NADH Model Compound: Synthesis and Enantioselective Reduction of Benzoylformates to the Corresponding Mandelates
Molecules 2007, 12, 979-987 (PDF format 101 K)

Shujian Qi, Kehui Shi, Hongyin Gao, Qiancai Liu * and Hong Wang
Department of Chemistry and Institute of Medicinal Chemistry, East China Normal University, 3663 Zhongshan Rd (N), Shanghai 200062, P. R. China
* Author to whom correspondence should be addressed; E-mail: [email protected]; Phone:
(+86)-21-62233490; Fax: (+86)-21-62232414
Received: 8 February 2007; in revised form: 10 May 2007 / Accepted: 10 May 2007 / Published: 12 May 2007
Full Paper: Synthesis and Fluorescence Properties of 5,7-Diphenylquinoline and 2,5,7-Triphenylquinoline Derived from m-Terphenylamine
Molecules 2007, 12, 988-996 (PDF format 103 K)

Panagiota Papadopoulou ¹, Olga Tzakou ^1,*, Constantinos Vagias ¹, Panagiotis Kefalas ² and Vassilios Roussis ¹
1 University of Athens, Department of Pharmacy, Division of Pharmacognosy and Chemistry of Natural Products, Panepistimioupoli Zographou, Athens, 157 71, Greece; E-mails: [email protected] (P. Papadopoulou); [email protected] (C. Vagias); [email protected] (V. Roussis)
2 Department of Food Quality and Chemistry of Naturals Products, Mediterranean Agronomic Institute of Chania, Alsyllion Agrokepiou, Chania, 73100, Crete, Greece;
E-mail: [email protected] (P. Kefalas)
* Author to whom correspondence should be addressed; e-mail: [email protected]; Tel: +210 7274591; Fax: +210 7274591
Received: 27 March 2007; in revised form: 7 May 2007 / Accepted: 11 May 2007 / Published: 12 May 2007
Full Paper: β-Orcinol Metabolites from the Lichen Hypotrachyna revoluta
Molecules 2007, 12, 997-1005 (PDF format 103 K)

Ivona Jasprica ¹, Mirza Bojic ¹, Ana Mornar ¹, Erim Besic ², Kajo Bucan ³ and Marica Medic-Saric ^1,*
1 Department of Medicinal Chemistry, Faculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovacica 1, 10000 Zagreb, Croatia
2 Department of Biophysics, Faculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovacica 1, 10000 Zagreb, Croatia
3 Split Clinical Hospital, Spinciceva 1, 21000 Split, Croatia
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel: (+385) 1 4818 304; Fax: (+385) 1 4856 201
Received: 10 April 2007; in revised form: 26 April 2007 / Accepted: 2 May 2007 / Published: 15 May 2007
Full Paper: Evaluation of Antioxidative Activity of Croatian Propolis Samples Using DPPH· and ABTS·⁺ Stable Free Radical Assays
Molecules 2007, 12, 1006-1021 (PDF format 199 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Maria Tsoukatou ¹, Jean Philippe Maréchal ^2,3, Claire Hellio ⁴, Irena Novaković ⁵, Srdan Tufegdzic ⁵, Dusan Sladić ⁵, Miroslav J. Gašić ^5,6, Anthony S. Clare ², Constantinos Vagias ¹ and Vassilios Roussis ^1,*
1 University of Athens, School of Pharmacy, Department of Pharmacognosy & Chemistry of Natural Products, Panepistimiopolis Zografou, Athens, GR 15771, Greece; E-mails: [email protected]; [email protected]
2 Newcastle University, School of Marine Science and Technology, Ridley Building, Newcastle upon Tyne NE1 7RU, U.K.; E-mail: [email protected]; [email protected]
3 Observatoire de Milieu Marin Martiniquais, 3 Avenue Condorcet, 97200 Fort de France, Martinique, French West Indies
4 Portsmouth University, School of Biological Sciences, King Henry Building, Portsmouth PO1 2DY, U.K.; E-mail: [email protected]
5 Institute of Chemistry, Technology and Metallurgy, Department of Chemistry, Njegoseva 12, 11000
Belgrade, Serbia and Montenegro; E-mails: [email protected]; [email protected]; [email protected]; [email protected]
6 Faculty of Chemistry, University of Belgrade, Studentski trg 12-16, 11000 Belgrade, Serbia and Montenegro
* Author to whom correspondence should be addressed; [email protected].
Received: 23 April 2007; in revised form: 13 May 2007 / Accepted: 14 May 2007 / Published: 15 May 2007
Full Paper: Evaluation of the Activity of the Sponge Metabolites Avarol and Avarone and their Synthetic Derivatives Against Fouling Micro- and Macroorganisms
Molecules 2007, 12, 1022-1034 (PDF format 94 K)

Charles Mutai ^1,2, Dennis Abatis ¹, Constantinos Vagias ^1,*, Dimitri Moreau ³, Christos Roussakis ³ and Vassilios Roussis ¹
1 University of Athens, Department of Pharmacy, Division of Pharmacognosy and Chemistry of Natural Products, Panepistimiopolis Zografou, Athens 157 71, Greece; E-mails: [email protected], [email protected], [email protected]
2 Kenya Medical Research Institute, Centre for Traditional Medicine and Drug Research, P.O Box 54840, Nairobi, Kenya
3 ISOMer, Laboratoire de Pharmacogénomique Marine, Faculté de Pharmacie, 1 Rue Gaston Veil, F-44035 Nantes, France; E-mails: [email protected], [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected],
Received: 7 April 2007; in revised form: 12 May 2007 / Accepted: 14 May 2007 / Published: 15 May 2007
Full Paper: Lupane Triterpenoids from Acacia mellifera with Cytotoxic Activity
Molecules 2007, 12, 1035-1044 (PDF format 85 K)

Isao Kubo*, Teruhiko Nitoda and Ken-ichi Nihei
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720-3114, USA
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 12 April 2007; in revised form: 14 May 2007 / Accepted: 14 May 2007 / Published: 15 May 2007
Full Paper: Effects of Quercetin on Mushroom Tyrosinase and B16-F10 Melanoma Cells
Molecules 2007, 12, 1045-1056 (PDF format 208 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Brenda Modak ^1,*, Macarena Rojas ¹, René Torres ¹, Jesús Rodilla ² and Federico Luebert ³
1 Universidad de Santiago de Chile. Facultad de Química y Biología. Departamento de Ciencias del Ambiente. Casilla 40, correo 33, Santiago, Chile, Tel. (+56)-02-6812575; Fax. (+56)-02-6812108; E-mails: [email protected]; [email protected]
2 Departamento de Química, Universidade da Beira Interior,. U. I&D Materiais Textêis e do Papel. 6201-001Covilhã, Portugal; E-mail: [email protected]
3 Universidad de Chile. Facultad de Ciencias Forestales. Departamento de Silvicultura. Casilla 9206, Santiago, Chile; E-mail: [email protected]
* Author to whom correspondence should be addressed; e-mail: [email protected]
Received: 5 April 2007; in revised form: 15 May 2007 / Accepted: 15 May 2007 / Published: 21 May 2007
Communication: Antioxidant Activity of a New Aromatic Geranyl Derivative of the Resinous Exudates from Heliotropium glutinosum Phil.
Molecules 2007, 12, 1057-1063 (PDF format 58 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Petr Jansa ^1,2, Vladimír Macháček ^1,*, Petr Nachtigall ², Vladimír Wsól ³ and Markéta Svobodová ¹
1 Department of Organic Chemistry, Faculty of Chemical Technology, University of Pardubice, Nám. Čs. legií 565, 53210 Pardubice, Czech Republic
2 present address: Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 16610 Praha 6, Czech Republic; E-mail: [email protected]
3 Department of Biochemical Sciences, Faculty of Pharmacy, Charles University, Heyrovského 1203, 50005 Hradec Králové, Czech Republic
^† Dedicated to professor Jaromír Kaválek in occasion of his 70th birthday.
* Author to whom correspondence should be addressed: [email protected]
Received: 27 March 2007; in revised form: 11 May 2007 / Accepted: 11 May 2007 / Published: 21 May 2007
Full Paper: Coordination Compounds Based on 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic Acid ^†
Molecules 2007, 12, 1064-1079 (PDF format 210 K)

Nora H. Al-Sha’alan
Department of Chemistry, Education College for Girls, Scientific Departments, 11322 Riyadh, P. O. 240549, Kindom of Saudi Arabia. E-mail: [email protected]; Fax: 0096612489254
Received: 17 April 2007; in revised form: 9 May 2007 / Accepted: 11 May 2007 / Published: 21 May 2007
Full Paper: Antimicrobial Activity and Spectral, Magnetic and Thermal Studies of Some Transition Metal Complexes of a Schiff Base Hydrazone Containing a Quinoline Moiety
Molecules 2007, 12, 1080-1091 (PDF format 92 K)

Guillermo Schmeda-Hirschmann ^1,*, Carlos Aranda ^1,2, Marcela Kurina ³, Jaime A. Rodríguez ⁴ and Cristina Theoduloz ⁴
1 Laboratorio de Química de Productos Naturales, Instituto de Química de Recursos Naturales, Universidad de Talca, Casilla 747, Talca, Chile
2 Current address: Centro de Investigación y Desarrollo de Recursos y Ambientes Costeros, Universidad de Los Lagos, Casilla 557, Puerto Montt, Chile
3 INTEQUI-CONICET, Laboratorio de Química Orgánica, Universidad Nacional de San Luis, Chacabuco y Pedernera 5700, San Luis, Argentina
4 Depto. de Ciencias Básicas Biomédicas, Facultad de Ciencias de la Salud, Universidad de Talca, Casilla 747, Talca, Chile
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel: (+ 56) 71 200288; Fax: (+ 56) 71 200448
Received: 20 April 2007; in revised form: 18 May 2007 / Accepted: 19 May 2007/ Published: 21 May 2007
Full Paper: Biotransformations of Imbricatolic Acid by Aspergillus niger and Rhizopus nigricans Cultures
Molecules 2007, 12, 1092-1100 (PDF format 96 K)

Róbson Ricardo Teixeira ^1,2, Luiz Cláudio Almeida Barbosa ^1,*, Célia Regina Alvares Maltha ¹, Marcelo Eça Rocha ¹, Daniel Pereira Bezerra ₃, Letícia Veras Costa-Lotufo ³, Cláudia Pessoa ³ and Manoel Odorico Moraes ³
1 Department of Chemistry, Federal University of Viçosa, Av. P.H. Rolfs, S/N, CEP 36570-000, Viçosa, MG, Brazil
2 Department of Chemistry, Federal University of Minas Gerais, Av. Antônio Carlos, 6627, CEP 31270-901, Belo Horizonte, MG, Brazil
3 Department of Physiology and Pharmacology, Federal University of Ceará, Rua Coronel Nunes de Melo, 1127, CEP 60431-970, Fortaleza, CE, Brazil
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel.: (+55) 31 3899 3068; Fax: (+55) 31 3899 3065
Received: 26 April 2007; in revised form: 21 May 2007 / Accepted: 21 May 2007 / Published: 24 May 2007
Full Paper: Synthesis and Cytotoxic Activity of Some 3-Benzyl-5-Arylidenefuran-2(5H)-ones
Molecules 2007, 12, 1101-1116 (PDF format 192 K)

Xuehui Liu and Yuxin Cui *
State Key Laboratory of Nature and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100083, P. R. China; E-mails: [email protected] (for X. Liu)
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 12 April 2007; in revised form: 13 May 2007 / Accepted: 14 May 2007 / Published: 24 May 2007
Full Paper: Structure Elucidation of a Pyrazolo[3,4]pyran Derivative by NMR Spectroscopy
Molecules 2007, 12, 1117-1124 (PDF format 481 K)

Seikwan Oh ¹, Hyung–In Moon ², Il–Hong Son ² and Jae–Chul Jung ^1,*
1 Department of Neuroscience and Medical Research Institute, College of Medicine, Ewha Womans University, Seoul 158–710, South Korea.
2 Department of Neuroscience and Inam Neuro Science Research Center, Wonkwang University Sanbon Medical Center, Sanbondong, Gunpocity, Kyunggido, 435-040, South Korea. E-mails:
[email protected] (Hyung–In Moon); [email protected] (Il–Hong Son)
* To whom correspondence should be addressed; [email protected]
Received: 17 April 2007; in revised form: 18 May 2007 / Accepted: 18 May 2007 / Published: 24 May 2007
Full Paper: Synthesis of Sulfonamides and Evaluation of Their Histone Deacetylase (HDAC) Activity
Molecules 2007, 12, 1125-1135 (PDF format 84 K)

Xiang-Lin Zhao ^†, Yan-Fang Zhao ^‡, Shu-Chun Guo, Hai-Sheng Song, Ding Wang and Ping Gong *
School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, 110016 Shenyang, Liaoning, P. R. China; Fax: (+86) 24-23986426/23882925, Phone: (+86) 24-23986426; E-mail: † [email protected]; ‡ [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 8 May 2007 / Accepted: 24 May 2007 / Published: 25 May 2007
Full Paper: Synthesis and Anti-tumor Activities of Novel [1,2,4]triazolo[1,5-a]pyrimidines
Molecules 2007, 12, 1136-1146 (PDF format 106 K)

Il Hong Son, Yong Hoon Park, Sung Ik Lee, Hyun Duk Yang and Hyung-In Moon*
Department of Neuroscience and, Inam Neuroscience Research Center, Sanbon Medical Center, Wonkwang University, Gunpo-city, Kyunggido, 435-040, South Korea
* To whom correspondence should be addressed; [email protected]; Fax. (+82)-313902414
Received: 2 May 2007; in revised form: 6 May 2007 / Accepted: 7 May 2007 / Published: 25 May 2007
Full Paper: Neuroprotective Activity of Triterpenoid Saponins from Platycodi radix Against Glutamate-induced Toxicity in Primary Cultured Rat Cortical Cells
Molecules 2007, 12, 1147-1152 (PDF format 39 K)

Ana Paula Pereira ¹, Isabel C.F.R. Ferreira ¹, Filipa Marcelino ¹, Patricia Valentão ², Paula B. Andrade ², Rosa Seabra ², Leticia Estevinho ¹, Albino Bento ¹ and José Alberto Pereira ^1,*
1 CIMO / Escola Superior Agrária, Instituto Politécnico de Bragança, Campus Sta Apolónia, Apt. 1172, 5301-855 Bragança, Portugal
2 REQUIMTE / Serviço de Farmacognosia, Faculdade de Farmácia da Universidade do Porto, Rua Aníbal Cunha, 164, 4050-047 Porto, Portugal
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 23 February 2007; in revised form: 24 May 2007 / Accepted: 24 May 2007 / Published: 26 May 2007
Full Paper: Phenolic Compounds and Antimicrobial Activity of Olive (Olea europaea L. Cv. Cobrançosa) Leaves
Molecules 2007, 12, 1153-1162 (PDF format 73 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Dong-Li Li ^1,2, Xiao-Ming Li ¹, Ze-Yu Peng ^1,† and Bin-Gui Wang ^1,*
1 Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Nanhai Road 7, Qingdao, 266071, P.R. China; E-mail: [email protected]
2 Graduate School of Chinese Academy of Sciences, Beijing, 100049, P.R. China
† Visiting undergraduate student from the Ocean University of China
* Author to whom correspondence should be addressed; Tel.: +86-532-82898553. E-mail: [email protected]
Received: 18 April 2007; in revised form: 15 May 2007 / Accepted: 16 May 2007 / Published: 26 May 2007
Full Paper: Flavanol Derivatives from Rhizophora stylosa and Their DPPH Radical Scavenging Activity
Molecules 2007, 12, 1163-1169 (PDF format 74 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Heru Chen *, Xianbin Zhong and Jin Wei
Department of Chemistry, School of Sciences, Shantou University, Shantou, Guangdong 515063, P. R. China
* Author to whom correspondence should be addressed; e-mail: [email protected]; Tel. (+86) 754 2902772; Fax (+86) 754 2902767
Received: 10 May 2007; in revised form: 24 May 2007 / Accepted: 25 May 2007 / Published: 26 May 2007
Full Paper: Stereoselective Syntheses of Fluorescent Non-Natural Aromatic Amino Acids Based on Asymmetric Michael Additions
Molecules 2007, 12, 1170-1182 (PDF format 135 K)

Ales Marek, Jiri Kulhanek, Miroslav Ludwig and Filip Bures*
Department of Organic Chemistry, Faculty of Chemical Technology, University of Pardubice, nam. Cs. legii 565, Pardubice, 53210, Czech Republic
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 11 May 2007; in revised form: 22 May 2007 / Accepted: 23 May 2007 / Published: 30 May 2007
Full Paper: Facile Synthesis of Optically Active Imidazole Derivatives
Molecules 2007, 12, 1183-1190 (PDF format 72 K)
(This paper belongs to Special Issue on Heterocycles)

Ruogu Peng, Feng Wang and Yaowu Sha*
The Key Laboratory of Bioorganic Phosphorous Chemistry and Chemical Biology, Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China; E-mail: [email protected] (for Ruogu Peng)
* Author to whom correspondence should be addressed. E-mail: [email protected]
Received: 4 April 2007; in revised form: 21 May 2007 / Accepted: 29 May 2007 / Published: 31 May 2007
Communication: Synthesis of 5-Dialkyl(aryl)aminomethyl-8-hydroxyquinoline Dansylates as Selective Fluorescent Sensors for Fe³⁺
Molecules 2007, 12, 1191-1201 (PDF format 218 K)
Publisher's Note added on 16 June 2007: a new version with corrections in Figure 1 was uploaded. The original file uploaded on 31 May 2007 is still available upon request. We apologize for any inconvenience.

Shih-Lun Lin, Pei-Yu Kuo and Ding-Yah Yang*
Department of Chemistry and Center for Nanoscience and Technology, Tunghai University, 181, Taichung-Kang Rd. Sec.3, Taichung, Taiwan 407
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel.: 886-4-2359-7613; Fax: 886-4-2359-0426
Received: 6 June 2007; in revised form: 1 July 2007/ Accepted: 1 July 2007 / Published: 6 July 2007
Full Paper: Design and Synthesis of a Coumarin-based Acidichromic Colorant
Molecules 2007, 12, 1316-1324 (PDF format 105 K)

Yun-Qian Zhang ¹, Qian-Jiang Zhu ¹, Sai-Feng Xue ¹ and Zhu Tao ^1,2,*
1 Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Guizhou University, Guiyang 550025, People’s Republic of China
2 Institute of Applied Chemistry, Guizhou University, Guiyang, 550025, People’s Republic of China
* Author to whom correspondence should be addressed; e-mail: [email protected]; Tel. (+86) 851 362 3903; Fax (+86) 851 362 0906
Received: 2 June 2007; in revised form: 3 July 2007 / Accepted: 3 July 2007 / Published: 6 July 2007
Full Paper: Chlorine Anion Encapsulation by Molecular Capsules Based on Cucurbit[5]uril and Decamethylcucurbit[5]uril
Molecules 2007, 12, 1325-1333 (PDF format 156 K)

Rajesh Kumar, Arvind K. Gupta and Mahabir P. Kaushik *
Process Technology Development Division, Defence R & D Establishment, Jhansi Road, Gwalior 474002 (MP) India; Tel. (+91)-751-2343972; Fax (+91)-751-2341148
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 16 April 2007; in revised form: 16 May 2007 / Accepted: 16 May 2007 / Published: 9 July 2007
Full Paper: A Novel and Efficient Synthesis of N,N-Dialkylaminoisopropyl- and O-alkylisopropyl-2-(1-alkyl-2-oxopropylidene)phosphonohydrazido Oximes - Potential Marine Fish Toxin Analogues. Part 1
Molecules 2007, 12, 1334-1340 (PDF format 53 K)

Hitendra N. Karade, Manisha Sathe and M. P. Kaushik*
Discovery Center, Process Technology Development Division, Defence R & D Establishment,
Jhansi Road, Gwalior 474002 (MP) India
* Author to whom correspondence should be addressed; e-mail: [email protected]; Tel. +91-751-2343972, Fax +91-751-2341148
Received: 21 May 2007; in revised form: 20 June 2007 / Accepted: 2 July 2007 / Published: 9 July 2007
Full Paper: Synthesis of 4-Aryl Substituted 3,4-Dihydropyrimidinones Using Silica-chloride Under Solvent Free Conditions
Molecules 2007, 12, 1341-1351 (PDF format 78 K)

Regina M. S. Pereira ^1,*, Norma E. D. Andrades ¹, Niraldo Paulino ¹, Alexandra C. H. F. Sawaya ¹, Marcos. N. Erbelin ², Maria C. Marcucci ¹, Giovani Marino Favero ³, Estela Maria Novak ³ and Sérgio Paulo Bydlowski ³
1 Department of Pharmacy, Bandeirante University of São Paulo, Rua Maria Cândida 1813, São Paulo, SP, Brazil
2 Thomson Mass Spectrometry Laboratory, Institute of Chemistry, State University of Campinas, UNICAMP, P.O.Box 6154, 13084-971 Campinas, SP, Brazil.
3 Fundação Pró-Sangue Hemocentro de São Paulo. Av. Dr. Eneas Carvalho de Aguiar 155 –1 andar, sl. l43, SP, Brazil
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel: + 55- 11-69679147; Fax: + 55-11-69679129
Received: 15 May 2007; in revised form: 20 June 2007 / Accepted: 3 July 2007 / Published: 9 July 2007
Full Paper: Synthesis and Characterization of a Metal Complex Containing Naringin and Cu, and its Antioxidant, Antimicrobial, Antiinflammatory and Tumor Cell Cytotoxicity
Molecules 2007, 12, 1352-1366 (PDF format 87 K)

Christina Vafiadi ¹, Evangelos Topakas ¹, Edwin J. Bakx ², Henk A. Schols ² and Paul Christakopoulos ^1,*
1 Biotechnology Laboratory, School of Chemical Engineering, National Technical University of Athens, 5 Iroon Polytechniou Str, Zografou Campus, 15700, Athens Greece
2 Wageningen University, Department of Agrotechnology and Food Sciences, Laboratory of Food Chemistry,P.O. Box 8129, 6700 EV Wageningen, The Netherlands
* Author to whom correspondence should be addressed; Tel: +30-210-7723231; fax: +30-210-7723163; e-mail: [email protected]
Received: 12 June 2007; in revised form: 3 July 2007 / Accepted: 3 July 2007 / Published: 9 July 2007
Full Paper: Structural Characterisation by ESI-MS of Feruloylated Arabino-oligosaccharides Synthesised by Chemoenzymatic Esterification
Molecules 2007, 12, 1367-1375 (PDF format 221 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Cherie A. Motti ^1,*, Marie-Lise Bourguet-Kondracki ^2,†, Arlette Longeon ², Jason R. Doyle ¹, Lyndon E. Llewellyn ¹, Dianne M. Tapiolas ¹ and Ping Yin ^3,‡
1 Australian Institute of Marine Science, Townsville, Queensland, 4810, Australia
2 Laboratoire de Chimie et Biochimie des Substances Naturelles, Muséum National d’Histoire Naturelle, 57 rue Cuvier (CP 54), Paris, 75005, France ; †E-mail: [email protected]
3 Nufarm Australia Limited, Department of Chemistry, Macquarie University, North Ryde, NSW, 2109, Australia; ‡E-mail: [email protected]
* Author to whom correspondence should be addressed; Tel: + 61-7-4753 4143; Fax: + 61-7-4772 5852; E-mail: [email protected]
Received: 18 June 2007; in revised form: 6 July 2007 / Accepted: 9 July 2007 / Published: 11 July 2007
Full Paper: Comparison of the Biological Properties of Several Marine Sponge-Derived Sesquiterpenoid Quinones
Molecules 2007, 12, 1376-1388 (PDF format 92 K)

Cynthia P. Tidwell ^1,*, Prakash Bharara ^1,†, Gretchen Rudeseal ¹, Tiffany Rudeseal ¹, Frank H. Rudeseal, Jr. ¹, Christine A. Simmer ¹, Dugald McMillan ¹, Katherine Lanier ¹, L. Dalila Fondren ¹, LaTasha L. Folmar ¹ and Ken Belmore ²
1 Department of Biology, Chemistry, and Mathematics, University of Montevallo, Station 6480 Montevallo, Alabama 35115, U.S.A.; † E-mail: [email protected]
2 Department of Chemistry, University of Alabama, Box 870336 Tuscaloosa, Alabama 35487, U.S.A.; E-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected].
Received: 30 May 2007; in revised form: 8 July 2007 / Accepted: 9 July 2007 / Published: 11 July 2007
Full Paper: Synthesis and Characterization of 5,10,15,20-Tetra[3-(3-trifluoromethyl)phenoxy] Porphyrin
Molecules 2007, 12, 1389-1398 (PDF format 67 K)
(This paper belongs to Special Issue on Heterocycles)

Zoubida Chemat-Djenni ^1,2,*, Boudjema Hamada ¹ and Farid Chemat ³
1 Laboratoire de Synthèse Pétrochimique, Faculté des Hydrocarbures et de la Chimie, Université M’Hamed Bouguerra, 35000 Boumerdès, Algeria
2 Faculté de Médecine, Université Saad Dahlab, 09000 Blida, Algeria
3 Université d’Avignon et des Pays de Vaucluse, UMR A408 INRA-UAPV, 33 rue Louis Pasteur 84029 Avignon, France
* Author to whom correspondence should be addressed. E-mail: [email protected]
Received: 15 June 2007; in revised form: 8 July 2007 / Accepted: 9 July 2007 / Published: 11 July 2007
Full Paper: Atmospheric Pressure Microwave Assisted Heterogeneous Catalytic Reactions
Molecules 2007, 12, 1399-1409 (PDF format 107 K)

Lida Fotouhi ^1,*, Saeed Dehghanpour ¹, Majid M. Heravi ¹ and Mahboobeh Dashti Ardakani ²
1 Department of Chemistry, School of Science, Azzahra University, P.O.Box 1993891176, Tehran, Iran
2 Institute and Outpatient Clinic for Occupation and Social Medicine of the Justus-Liebig-University of Giessen, Aulweg 129 III, 35392 Giessen, Federal Republic of Germany; Email: [email protected]
* Author to whom correspondence should be addressed; E-mails: [email protected] or [email protected]
Received: 6 June 2007; in revised form: 9 July 2007 / Accepted: 10 July 2007 / Published: 12 July 2007
Full Paper: Electrochemical Synthesis and Structural Characterization of a Novel Mixed-valence Copper (I)-copper (II) Complex: {[Bis(ethylenediamine) Copper (II)] Bis[diiodocuprate (I)]}
Molecules 2007, 12, 1410-1419 (PDF format 164 K)

Yong Rok Lee*, Xue Wang and Likai Xia
School of Chemical Engineering and Technology, Yeungnam University, Gyeongsan 712-749, Korea
* Author to whom correspondence should be addressed; Tel: +82-53-8102529; Fax: +82-53-8104631; E-mail: [email protected]
Received: 29 June 2007; in revised form: 10 July 2007 / Accepted: 10 July 2007 / Published: 12 July 2007
Full Paper: An Efficient and Rapid Synthetic Route to Biologically Interesting Pyranochalcone Natural Products
Molecules 2007, 12, 1420-1429 (PDF format 92 K)

Strahil Berkov ¹, Ricardo Reyes-Chilpa ², Carles Codina ¹, Francesc Viladomat ¹ and Jaume Bastida ^1,*
1 Departament de Productes Naturals, Biologia Vegetal i Edafologia, Facultat de Farmàcia, Universitat de Barcelona, Av. Diagonal 643, 08028 Barcelona, Spain.
2 Instituto de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, Coyoacán 04510, México DF, México.
* Author to whom correspondence should be addressed; E-mail: [email protected]; Phone: (+34) 934024493.
Received: 18 June 2007; in revised form: 10 July 2007 / Accepted: 10 July 2007 / Published: 12 July 2007
Communication: Revised NMR data for Incartine: an Alkaloid from Galanthus elwesii
Molecules 2007, 12, 1430-1435 (PDF format 64 K)

Shu-Kun Lin
Editorial: Non-Open Access and Its Adverse Impact on Molecules
Molecules 2007, 12, 1436-1437 (PDF format 16 K, HTML format)

Hossien A. Oskooie*, Majid M. Heravi* and Farahnaz K. Behbahani
Department of Chemistry, School of Sciences, Azzahra University, Vanak, Tehran, Iran
* Authors to whom correspondence should be addressed; E-mails: [email protected]; [email protected]
Received: 8 March 2007; in revised form: 1 July 2007 / Accepted: 2 July 2007 / Published: 19 July 2007
Communication: A Facile, Mild And Efficient One-Pot Synthesis of 2-Substituted Indole Derivatives Catalyzed By Pd(PPh₃)₂Cl ₂
Molecules 2007, 12, 1438-1446 (PDF format 56 K)

Atia-tun-Noor ¹, Itrat Fatima ¹, Ijaz Ahmad ², Abdul Malik ^1,*, Nighat Afza ³, Lubna Iqbal ³, Mehreen Latif ³ and Sher Bahadar Khan ¹
1 International Centre for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan
2 Medicinal Botanic Centre, PCSIR Labs. Complex Peshawar, Peshawar, N.W.F.P, Pakistan
3 Pharmaceutical Research Centre, PCSIR Labs. Complex, Karachi-75280, Pakistan
* Author to whom correspondence should be addressed; Tel: +92-21-4824926; Fax: +92-21-4819018, 4819019; e-mail: [email protected]
Received: 2 July 2007; in revised form: 12 July 2007 / Accepted: 12 July 2007 / Published: 19 July 2007
Full Paper: Leufolins A and B, Potent Butyrylcholinesterase-inhibiting Flavonoid Glucosides from Leucas urticifolia
Molecules 2007, 12, 1447-1454 (PDF format 83 K)

Zhen Mao ^{1, 2,†}, Yuan-lin Zheng ^1,*, Yan-qiu Zhang , Bao-ping Han ^1,2, Xiao-wan Zhu ¹, Qing Chang ¹ and Xiang-bin Hu ¹
1 Key Laboratory for Biotechnology on Medicinal Plants of Jiangsu Province, School of Life Science, Xuzhou Normal University, Xuzhou 221116, Jiangsu Province, P. R. China; E-mails:
[email protected] (Zhen Mao); [email protected] (Yuan-lin Zheng)
2 School of Environment Science and Spatial Informatics, China University of Mining and Technology, Xuzhou 221008, Jiangsu Province, P. R. China
* Author to whom correspondence should be addressed; E-mail addresses: [email protected], [email protected]; Tel: (+86) 516 83500348; Fax: (+ 86) 516 83500348
Received: 30 May 2007; in revised form: 3 July 2007 / Accepted: 13 July 2007 / Published: 19 July 2007
Full Paper: The Anti-apoptosis Effects of Daidzein in the Brain of D-Galactose Treated Mice
Molecules 2007, 12, 1455-1470 (PDF format 309 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Augusto Rivera * and Jaime Rios-Motta
Departamento de Química, Universidad Nacional de Colombia, Carrera 30 No. 45-03, Ciudad
Universitaria, Bogotá, D.C., Colombia. E-mail: [email protected]
* Author to whom correspondence should be addressed. E-mail: [email protected]
Received: 10 May 2005; in revised form: 29 June 2007 / Accepted: 29 June 2007 / Published: 19 July 2007
Full Paper: Unusual Reactivity Patterns of 1,3,6,8-Tetraazatricyclo-[4.4.1.1^3,8]-dodecane (TATD) Towards Some Reducing Agents: Synthesis of TMEDA
Molecules 2007, 12, 1471-1481 (PDF format 74 K)

Anna Corradi ¹, Cristina Leonelli ¹, Antonino Rizzuti ¹, Roberto Rosa ^1,*, Paolo Veronesi ¹, Romano Grandi ², Sara Baldassari ³ and Carla Villa 3
1 Dipartimento di Ingegneria dei Materiali e dell’Ambiente, Università degli Studi di Modena e Reggio Emilia, Via Vignolese, 905, 41100 Modena, Italy. FAX: +390592056243;
tel: +390592056247; e-mails: [email protected], [email protected], [email protected], [email protected]
2 Dipartimento di Chimica, Università degli Studi di Modena e Reggio Emilia, Via Campi, 183, 41100 Modena, Italy; e-mail: [email protected]
3 Dipartimento di Scienze Farmaceutiche dell’Università degli Studi di Genova, Viale Benedetto XV, 3, 16132 Genova, Italy; e-mails: [email protected], [email protected]
* Author to whom correspondence should be addressed; e-mail: [email protected]
Received: 31 May 2007; in revised form: 16 July 2007 / Accepted: 16 July 2007 / Published: 19 July 2007
Full Paper: New “Green” Approaches to the Synthesis of Pyrazole Derivatives
Molecules 2007, 12, 1482-1495 (PDF format 187 K)
(This paper belongs to Special Issue on Heterocycles)

Reşat Apak ^1,*, Kubilay Güçlü ^1,, Birsen Demirata ², Mustafa Özyürek ^1,, Saliha Esin Çelik ^1,, Burcu Bektaşoğlu ^1,, K. Işıl Berker ^1, and Dilek Özyurt ²
1 Istanbul University, Faculty of Engineering, Department of Chemistry, Avcilar, Istanbul 34320 Turkey; e-mails: [email protected], [email protected], [email protected], [email protected]
2 Istanbul Technical University, Faculty of Arts & Sciences, Department of Chemistry, Maslak, Istanbul Turkey; e-mail: [email protected], [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 30 June 2007; in revised form: 17 July 2007 / Accepted: 18 July 2007 / Published: 19 July 2007
Review: Comparative Evaluation of Various Total Antioxidant Capacity Assays Applied to Phenolic Compounds with the CUPRAC Assay
Molecules 2007, 12, 1496-1547 (PDF format 249 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Bruno Ndjakou Lenta ^1,2,*, Catherine Vonthron-Sénécheau ^3,*, Bernard Weniger ^4,*, Krishna Prasad Devkota ², Joseph Ngoupayo ⁵, Marcel Kaiser ⁶, Qamar Naz ⁷, Muhammad Iqbal Choudhary ⁷, Etienne Tsamo ⁵ and Norbert Sewald ^2,*
1 Department of Chemistry, Higher Teachers’ Training College, University of Yaoundé 1, P.O. Box 47, Yaoundé, Cameroon
2 Department of Chemistry, Organic and Bioorganic Chemistry, Bielefeld University, P.O.Box100131, 33501 Bieleleld, Germany
3 Laboratoire de Biologie et Biotechnologies Marines, UMR M IFREMER 100, Université de Caen Basse Normandie, 14032 Caen, France
4 Laboratoire de Pharmacognosie et de Molécules Naturelles Bioactives, LC01 UMR 7175, Faculté de Pharmacie, Université Louis Pasteur, Strasbourg, BP 60024-67401 Illkirch cedex, France
5 Department of Organic Chemistry, Faculty of Science, University of Yaoundé 1, BP 812, Yaoundé, Cameroon.
6 Swiss Tropical Institute, Medical parasitology and Infection Biology, Socinstrasse 57, CH-4002 Basel, Switzerland
7 H.E.J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi-75270, Pakistan
* Authors to whom correspondence should be addressed: Tel: +49-(0)521 1062147, Fax: int. +49-(0)521-106 8094), E-mail: [email protected] (B. N. Lenta), [email protected] (B. Weniger), [email protected] (C. Vonthron-Sénécheau), [email protected] (N. Sewald)
Received: 15 May 2007; in revised form: 8 July 2007 / Accepted: 9 July 2007 / Published: 20 July 2007
Full Paper: Leishmanicidal and Cholinesterase Inhibiting Activities of Phenolic Compounds from Allanblackia monticola and Symphonia globulifera
Molecules 2007, 12, 1548-1557 (PDF format 57 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Mohammed H. Al-Huniti ¹, Mustafa M. El-Abadelah ¹, Jalal A. Zahra ^1,*, Salim S. Sabri ² and Arnd Ingendoh ³
1 Chemistry Department, Faculty of Science, The University of Jordan, Amman 11942, Jordan; E-mails: [email protected], [email protected]
2 University of Sharjah, Sharjah, P. O. Box 27272, United Arab Emirates (UAE); E-mail: [email protected]
3 Bruker Daltonik GmbH, Fahrenheitstr. 4, D-28359 Bremen, Germany; E-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]; Fax: +962-6 5348932; Tel.: +962-6 5355000 (ext. 22163)
Received: 4 June 2007; in revised form: 19 July 2007 / Accepted: 19 July 2007 / Published: 27 July 2007
Full Paper: Heterocycles [h]Fused onto 4-Oxoquinoline-3-Carboxylic Acid, Part IV. Convenient Synthesis of Substituted Hexahydro [1,4]Thiazepino[2,3-h]quinoline-9-carboxylic Acid and Its Tetrahydroquino[7,8-b]benzothiazepine Homolog
Molecules 2007, 12, 1558-1568 (PDF format 79 K)

Piyada Thipyapong ^1,*, Michael J. Stout ² and Jutharat Attajarusit ¹
1 Suranaree University of Technology, 111 University Ave., Muang District, Nakhon Ratchasima 30000, Thailand; E-mail: [email protected]
2 Department of Entomology, Louisiana State University, 402 Life Sciences Building, Louisiana State University, Baton Rouge, LA 70803, USA; E-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel: 66-44-224276; Fax 66-44-224150
Received: 30 May 2007; in revised form: 19 July 2007 / Accepted: 19 July 2007 / Published: 27 July 2007
Review: Functional Analysis of Polyphenol Oxidases by Antisense/Sense Technology
Molecules 2007, 12, 1569-1595 (PDF format 298 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Jian-yu Jin ¹, Li-xue Zhang ^2,*, An-jiang Zhang ², Xin-Xiang Lei ² and Jiang-Hai Zhu ¹
1 College of Education, Wenzhou University, Wenzhou 325035, P.R. China; E-mail: [email protected]
2 College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325027, P.R.China
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel: (+86) 577-88373073; Fax: (+86) 577-88339081
Received: 30 May 2007; in revised form: 25 July 2007 / Accepted: 25 July 2007 / Published: 27 July 2007
Full Paper: Synthesis and Biological Activity of Some Novel Derivatives of 4-Amino-3-(D-galactopentitol-1-yl)-5-mercapto-1,2,4-triazole
Molecules 2007, 12, 1596-1605 (PDF format 101 K)

Hengxing Liang ^1,2, Fukai Bao ³, Xiaoping Dong ², Rui Tan ⁴, Caijun Zhang ³, Qing Lu ¹ and Yongxian Cheng ^1,*
1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P. R. China
2 College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, P. R. China
3 Department of Microbiology and Immunology, Kunming Medical College, Kunming 650031, P. R. China
4 College of Bioengineering, Southwest Jiaotong University, Chengdu 610031, P. R. China
* Author to whom correspondence should be addressed; Tel./Fax: +86 871 5223048; E-mail: [email protected]
Received: 19 June 2007; in revised form: 3 July 2007 / Accepted: 3 July 2007 / Published: 27 July 2007
Full Paper: Antibacterial Thymol Derivatives Isolated from Centipeda minima
Molecules 2007, 12, 1606-1613 (PDF format 81 K)

Magali Cannac ¹, Vanina Pasqualini ^1,*, Stéphane Greff ², Catherine Fernandez ² and Lila Ferrat ¹
1 Laboratoire Systèmes Physiques de l’Environnement, U.M.R. C.N.R.S. 6134, Université de Corse, 20250 Corte, France; E-mails: [email protected] (Magali Cannac), [email protected] (Lila Ferrat)
2 Institut Méditerranéen d’Ecologie et Paléoécologie, U.M.R. C.N.R.S. 6116, Aix-Marseille Université, Centre de St. Jérôme, Case 421, 13397 Marseille, Cedex 20, France ; E-mails: [email protected] (Stéphane Greff), [email protected] (Catherine Fernandez)
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 30 May 2007; in revised form: 19 July 2007 / Accepted: 19 July 2007 / Published: 30 July 2007
Full Paper: Characterization of Phenolic Compounds in Pinus laricio Needles and Their Responses to Prescribed Burnings
Molecules 2007, 12, 1614-1622 (PDF format 44 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Eva H. Mørkved ^1,*, Jon A. Beukes ² and Frode Mo ^2,*
1 Department of Chemistry, Norwegian University of Science and Technology, N-7491 Trondheim, Norway.
2 Department of Physics, Norwegian University of Science and Technology, N-7491 Trondheim, Norway.
* Authors to whom correspondence should be addressed. E-mail: [email protected] or [email protected]
Received: 1 June 2007; in revised form: 20 July 2007 / Accepted: 20 July 2007 / Published: 30 July 2007
Full Paper: o-Quinonoid Heterocycles: Synthesis and Crystal Structure of 2,3-Dicyano-5,7-bismethylthieno[3,4-b]pyrazine
Molecules 2007, 12, 1623-1631 (PDF format 195 K)
(This paper belongs to Special Issue on Heterocycles)

Rajesh Kumar, Arvind K. Gupta and Mahabir P. Kaushik*
Process Technology Development Division, Defence R & D Establishment, Jhansi Road, Gwalior- 474002 (MP), India; Tel. (+91) 751-2343972; Fax (+91) 751-2341148
* Author to whom correspondence should be addressed; e-mail: [email protected]. For Part 1 of this series, see reference 13a.
Received: 6 July 2007; in revised form: 26 July 2007 / Accepted: 26 July 2007 / Published: 2 August 2007
Full Paper: Novel and Efficient Synthesis of N,N-Dialkylaminoand O-alkylphenyl-2-(1-alkyl/phenyl-2-oxopropylidene) Phosphonohydrazido Oximes - Potential Marine Fish Toxin Analogues. Part 2
Molecules 2007, 12, 1632-1640 (PDF format 59 K)

Giuseppe Gattuso*, Davide Barreca, Claudia Gargiulli, Ugo Leuzzi and Corrado Caristi*
Dipartimento di Chimica Organica e Biologica, Università di Messina, Salita Sperone 31, I-98166 Messina, Italy; E-mails: [email protected]; [email protected]; [email protected]
* Authors to whom correspondence should be addressed; E-mails: [email protected]; [email protected]
Received: 22 June 2007; in revised form: 30 July 2007 / Accepted: 31 July 2007 / Published: 3 August 2007
Review: Flavonoid Composition of Citrus Juices
Molecules 2007, 12, 1641-1673 (PDF format 359 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Kyle E. Litz
Applied Nanoworks, Inc. 9 University Place, Rensselaer, NY 12144, USA; E-mail: [email protected]
Received: 23 July 2007; in revised form: 2 August 2007 / Accepted: 3 August 2007 / Published: 4 August 2007
Communication: Aqueous Ti(IV)-Catalyzed Diels-Alder Reaction
Molecules 2007, 12, 1674-1678 (PDF format 27 K)

Alessandra Bendini ^1,*, Lorenzo Cerretani ¹, Alegria Carrasco-Pancorbo ², Ana Maria Gómez-Caravaca ², Antonio Segura-Carretero ², Alberto Fernández-Gutiérrez ² and Giovanni Lercker ¹
1 Department of Food Science, University of Bologna. P.zza Goidanich 60, I-47023 Cesena (FC), Italy; E-mails: [email protected]; [email protected]
2 Department of Analytical Chemistry, Faculty of Sciences, University of Granada, c/Fuentenueva s/n, E-18071 Granada, Spain; E-mails: [email protected]; [email protected]; [email protected];
[email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel. (+39) 0547338121; Fax: (+39) 0547382348
Received: 9 June 2007; in revised form: 2 August 2007/ Accepted: 2 August 2007 / Published: 6 August 2007
Review: Phenolic Molecules in Virgin Olive Oils: a Survey of Their Sensory Properties, Health Effects, Antioxidant Activity and Analytical Methods. An Overview of the Last Decade Alessandra
Molecules 2007, 12, 1679-1719 (PDF format 251 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Aliasghar Jarrahpour ^1,*, Dariush Khalili ¹, Erik De Clercq ², Chanaz Salmi ³ and Jean Michel Brunel ³
1 Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran
2 Rega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium
3 Laboratoire SESNAB, Faculté de St Jérôme, Case 342, Université Paul Cézanne, Av. Escadrille Normandie Niémen, 13397 Marseille cedex 20, France
* Author to whom correspondence should be addressed. e-mail: [email protected] or [email protected]
Received: 11 April 2007; in revised form: 13 May 2007 / Accepted: 15 May 2007 / Published: 7 August 2007
Full Paper: Synthesis, Antibacterial, Antifungal and Antiviral Activity Evaluation of Some New bis-Schiff Bases of Isatin and Their Derivatives
Molecules 2007, 12, 1720-1730 (PDF format 76 K)

Marco Calabresi, Patrizia Andreozzi, and Camillo La Mesa*
Dipartimento di Chimica and SOFT-INFM-CNR Research Centre, Università “La Sapienza”, P.le A. Moro 5, Roma, I-00185, Italy
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel. +39-06-491694 (direct); +39-06-49913707; Fax. +39-06-490631
Received: 9 May 2007; in revised form: 12 July 2007 / Accepted: 12 July 2007 / Published: 7 August 2007
Review: Supra-molecular Association and Polymorphic Behaviour In Systems Containing Bile Acid Salts
Molecules 2007, 12, 1731-1754 (PDF format 458 K)
(This paper belongs to Special Issue on Bile acids, edited by Dr. Erkki Kolehmainen)

Kamil Musilek ^1,2, Kamil Kuca ^1,3*, Vlastimil Dohnal ^1,4, Daniel Jun ^1,3, Jan Marek ² and Vit Koleckar ³
1 Department of Toxicology, Faculty of Military Health Sciences, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic
2 Faculty of Pharmacy in Hradec Kralove, Charles University in Prague, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic
3 Center of Advanced Studies, Faculty of Military Health Sciences, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic
4 Department of Food Technology, Mendel University of Agriculture and Forestry Brno, Zemedelska 1, 613 00 Brno, Czech Republic
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 25 June 2007; in revised form: 1 August 2007 / Accepted: 6 August 2007 / Published: 7 August 2007
Communication: Two Step Synthesis of a Non-symmetric Acetylcholinesterase Reactivator
Molecules 2007, 12, 1755-1761 (PDF format 50 K)

Augusto Gambacorta ^1,*, Daniela Tofani ^1,* and Antonella Migliorini ²
1 Dipartimento di Ingegneria Meccanica e Industriale, Università degli studi “Roma Tre”, via della Vasca Navale 79, 00146 Roma, Italy
2 Dipartimento di Chimica, Università “La Sapienza”, P.le Aldo Moro 5, 00185 Rome, Italy
* Authors to whom correspondence should be addressed; E-mails: [email protected], [email protected]
Received: 30 May 2007; in revised form: 31 July 2007 / Accepted: 1 August 2007 / Published: 8 August 2007
Full Paper: High-Yielding Synthesis of Methyl Orthoformate-Protected Hydroxytyrosol and Its Use in Preparation of Hydroxytyrosyl Acetate
Molecules 2007, 12, 1762-1770 (PDF format 89 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Elena Pérez-Mayoral ^1,2, Jordi Soler-Padrós ¹, Viviana Negri ¹, Sebastián Cerdán 3 and Paloma Ballesteros ^1,*
1 Laboratorio de Síntesis Orgánica e Imagen Molecular por Resonancia Magnética, Facultad de Ciencias, UNED, Paseo Senda del Rey 9, E-28040 Madrid, Spain
2 Departamento de Química Inorgánica y Química Técnica, Facultad de Ciencias, UNED, Paseo Senda del Rey 9, E-28040 Madrid, Spain
3 Laboratorio de Imagen Espectroscópica por Resonancia Magnética (LIERM), Instituto de Investigaciones Biomédicas “Alberto Sols”, CSIC/UAM, C/ Arturo Duperier 4, E-28029 Madrid, Spain
* Author to whom correspondence should be addressed; E-mail: [email protected]. Phone: (+34) 913987320. Fax: (+34) 913986697.
Received: 29 May 2007; in revised form: 3 August 2007/ Accepted: 3 August 2007 / Published: 9 August 2007
Review: Synthetic Approaches to Heterocyclic Ligands for Gd-Based MRI Contrast Agents
Molecules 2007, 12, 1771-1795 (PDF format 177 K)

Abdullah M. Asiri* and Khadija O. Badahdah
Chemistry Department, Faculty of Science, King Abdul Aziz University, Jeddah 21413, P. O. Box 80203, Saudi Arabia
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 24 May 2007; in revised form: 19 July 2007 / Accepted: 19 July 2007 / Published: 13 August 2007
Full Paper: Synthesis of Some New Anils: Part 1. Reaction of 2-Hydroxy-benzaldehyde and 2-Hydroxynaphthaldehyde with 2-Aminopyridene and 2-Aminopyrazine
Molecules 2007, 12, 1796-1804 (PDF format 67 K)

Muzaffer Alkan ¹, Haydar Yüksek ^1,*, Fatih İslamoğlu ², Şule Bahçeci ³, Mustafa Calapoğlu ¹, Mahfuz Elmastaş ⁴, Hüseyin Akşit ⁴ and Mustafa Özdemir 5
1 Education Faculty, Kafkas University, 36100 Kars, Turkey; Fax (+90)-474-2121185
2 Department of Chemistry, Rize University, Rize, Turkey
3 Fatih Education Faculty, Karadeniz Technical University, 61335 Trabzon, Turkey
4 Gaziosmanpasa University, Dept. of Chemistry, Tokat, Turkey
5 Department of Chemistry, Karadeniz Technical University, 61100 Trabzon, Turkey
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 28 May 2007; in revised form: 2 August 2007 / Accepted: 2 August 2007 / Published: 13 August 2007
Full Paper: A Study on 4-Acylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones
Molecules 2007, 12, 1805-1816 (PDF format 67 K)

Marijana Hranjec and Grace Karminski-Zamola*
Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, Marulićev trg 20, HR-10000 Zagreb, Croatia
* Author to whom correspondence should be addressed; E-mail: [email protected]; Phone: +385 1 4597 215; Fax: +385 1 4597 224
Received: 28 June 2007; in revised form: 20 July 2007 / Accepted: 20 July 2007 / Published: 13 August 2007
Full Paper: Synthesis of Novel Benzimidazolyl-substituted Acrylonitriles and Amidino-substituted Benzimidazo[1,2-a]Quinolines
Molecules 2007, 12, 1817-1828 (PDF format 94 K)

María P. Elizalde-González* and Socorro G. Hernández-Ogarcía
Centro de Química, Instituto de Ciencias, Universidad Autónoma de Puebla, Apdo. Postal J-55, 72571 Puebla, Pue. Mexico
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 21 March 2007; in revised form: 31 July 2007 / Accepted: 31 July 2007 / Published: 13 August 2007
Communication: Effect of Cooking Processes on the Contents of Two Bioactive Carotenoids in Solanum lycopersicum Tomatoes and Physalis ixocarpa and Physalis philadelphica Tomatillos
Molecules 2007, 12, 1829-1835 (PDF format 66 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Yoshinori Kadoma ¹, Wakako Kumada ²,Yuhta Asai ², Yoshiaki Sugita ², Ichiro Yokoe ² and Seiichiro Fujisawa ^2,*
1 Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Kandasurugadai, Chiyoda-ku, Tokyo 101-0062, Japan; E-mail: [email protected]
2 Faculty of Pharmaceutical Sciences, Josai University, Saitama 3500295; Meikai Unversity School of Dentistry, Sakado, Saitama 3500283 Japan; E-mails: wakako-216@ezweb. ne. jp (Kumada); [email protected] (Asai), [email protected] (Yokoe),
* Author to whom correspondence should be addressed; E-mail: fujisawa [email protected]
Received: 13 July 2007; in revised form: 9 August 2007 / Accepted: 9 August 2007 / Published: 13 August 2007
Full Paper: Radical-scavenging Activity of the Reaction Products of Isoeugenol with Thiol, Thiophenol, Mercaptothiazoline or Mercaptomethylimidazole Using the Induction Period Method
Molecules 2007, 12, 1836-1844 (PDF format 81 K)

Chieh-Chen Huang ^1,2, Wen-Bin Wu ¹, Jia-You Fang ³, Han-Sun Chiang ¹, Shao-Kuan Chen ⁴, Bing-Huei Chen ⁵, Ying-Ting Chen ¹ and Chi-Feng Hung^1,*
1 School of Medicine, Fu-Jen Catholic University, Taipei, Taiwan
2 Department of Dermatology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan
3 Pharmaceutics Laboratory, Graduate Institute of Natural Products, Chang Gung University, Kweishan, Taoyuan, Taiwan
4 Department of Surgery, Sijhih Cathay General Hospital, Taipei, Taiwan
5 Department of Nutrition and Food Sciences, Fu-Jen Catholic University, Taipei Hsien, Taiwan
* Author to whom correspondence should be addressed. E-mail: [email protected], Tel: +886 229052079, Fax: +886 2 29052096
Received: 25 May 2007; in revised form: 10 August 2007 / Accepted: 10 August 2007 / Published: 14 August 2007
Full Paper: (-)-Epicatechin-3-gallate, a Green Tea Polyphenol Is a Potent Agent Against UVB-induced Damage in HaCaT Keratinocytes
Molecules 2007, 12, 1845-1858 (PDF format 373 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Elina Sievänen
University of Jyväskylä, Department of Chemistry, P.O. Box 35, FIN-40014 University of Jyväskylä, Finland; E-mail: [email protected]
Received: 6 June 2007; in revised form: 13 August 2007 / Accepted: 14 August 2007 / Published: 16 August 2007
Review: Exploitation of Bile Acid Transport Systems in Prodrug Design
Molecules 2007, 12, 1859-1889 (PDF format 159 K)
(This paper belongs to Special Issue on Bile acids,edited by Dr. Erkki Kolehmainen)

Daniel G. Rivera ^1,2 and Ludger A. Wessjohann ^1,*
1 Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, D-06120, Halle/Saale, Germany
2 Center for Natural Products Study, Faculty of Chemistry, University of Havana, Havana 10400, Cuba
* Author to whom correspondence should be addressed: E-mail: [email protected]; Fax: +49 345 5582 1309; Tel: +49 345 5582 1301
Received: 24 May 2007 / Accepted: 15 August 2007 / Published: 17 August 2007
Full Paper: Synthesis of Novel Steroid-Peptoid Hybrid Macrocycles by Multiple Multicomponent Macrocyclizations Including Bifunctional Building Blocks (MiBs)
Molecules 2007, 12, 1890-1899 (PDF format 119 K)
(This paper belongs to Special Issue on Bile acids,edited by Dr. Erkki Kolehmainen)

Norbert Haider *, Tamara Kabicher, Johann Käferböck and Angelika Plenk
Department of Drug and Natural Product Synthesis, Faculty of Life Sciences, University of Vienna,
Althanstraße 14, A-1090 Vienna, Austria
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 2 August 2007; in revised form: 14 August 2007 / Accepted: 14 August 2007 / Published: 17 August 2007
Full Paper: Synthesis and In-vitro Antitumor Activity of 1-[3-(Indol-1-yl)prop-1-yn-1-yl]phthalazines and Related Compounds
Molecules 2007, 12, 1900-1909 (PDF format 77 K)

Sevim Rollas* and Ş. Güniz Küçükgüzel
Marmara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 34668, Turkey
* Author to whom correspondence should be addressed E-mail: [email protected]
Received: 13 March 2007; in revised form: 11 August 2007 / Accepted: 16 August 2007 / Published: 17 August 2007
Review: Biological Activities of Hydrazone Derivatives
Molecules 2007, 12, 1910-1939 (PDF format 185 K)

Emmanuel Tourneux ¹, Heinz Gornitzka ², Jean-Daniel Marty ^1,* and Nancy Lauth-de Viguerie ^1,*
1 Laboratoire des Interactions Moléculaires, Réactivité Chimique et Photochimique, UMR CNRS 5623, Université Paul Sabatier, 31062 Toulouse Cedex 9, France
2 Laboratoire Hétérochimie Fondamentale et Appliquée, UMR CNRS 5069, Université Paul Sabatier, 31062 Toulouse Cedex 9, France
* Authors to whom correspondence should be addressed; E-mail: [email protected]; E-mail: [email protected]
Received: 23 May 2007; in revised form: 19 July 2007 / Accepted: 19 July 2007 / Published: 20 August 2007
Full Paper: Palladate Salts from Chiral Pyridinium Ionic Liquids: Synthesis and Crystal Structures
Molecules 2007, 12, 1940-1949 (PDF format 146 K)
(This paper belongs to Special Issue on Heterocycles)

Elza Yamaguti-Sasaki ^1,‡, Lia Akina Ito ², Vanessa Cristina Dias Canteli ², Tânia Mara Antonelli Ushirobira ³, Tânia Ueda-Nakamura ¹, Benedito Prado Dias Filho ¹, Celso Vataru Nakamura ¹ and João Carlos Palazzo de Mello ^1,2,*
1 Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Estadual de Maringá, Av. Colombo, 5790, BR-87020-900, Maringá, PR, Brazil
2 Departamento de Farmácia e Farmacologia, Universidade Estadual de Maringá, Av. Colombo, 5790, BR-87020-900, Maringá, PR, Brazil
3 CCAS, Pontifícia Universidade Católica, Av. Tiradentes, 963, BR-87013-260, Maringá, PR, Brazil
‡ Part of the M.Sc. Thesis.
* Author to whom correspondence should be addressed; E-mail: [email protected]; Fax: (+55)-44-3261-4999;
Received: 28 May 2007; in revised form: 1 August 2007 / Accepted: 1 August 2007 / Publsihed: 20 August 2007
Full Paper: Antioxidant Capacity and In Vitro Prevention of Dental Plaque Formation by Extracts and Condensed Tannins of Paullinia cupana
Molecules 2007, 12, 1950-1963 (PDF format 105 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Kamil Kuca ^1,2, Kamil Musilek ^2,3,*, Martin Paar ³, Daniel Jun ^1,2, Petr Stodulka ¹, Martina Hrabinova ¹ and Jan Marek ^2,3
1 Center of Advanced Studies, Faculty of Military Health Sciences, Hradec Kralove, Czech Republic
2 Department of Toxicology, Faculty of Military Health Sciences, Hradec Kralove, Czech Republic
3 Department of Pharmaceutical Chemistry and Drug Control, Faculty of Pharmacy, Hradec Kralove, Czech Republic
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel.: 00420-973-521-523; Fax: 00420-495-518-094.
Received: 31 July 2007; in revised form: 14 August 2007 / Accepted: 14 August 2007 / Published: 20 August 2007
Communication: Targeted Synthesis of 1-(4-Hydroxyiminomethylpyridinium)-3-pyridiniumpropane Dibromide – A New Nerve Agent Reactivator
Molecules 2007, 12, 1964-1972 (PDF format 56 K)

Mikiji Miyata,* Norimitsu Tohnai, and Ichiro Hisaki
Department of Material and Life Science, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan
* Author to whom correspondence should be addressed; E-mail: [email protected]; Phone and Fax: +81-6-6879-7406
Received: 30 June 2007; in revised form: 20 August 2007 / Accepted: 20 August 2007 / Published: 22 August 2007
Review: Supramolecular Chirality in Crystalline Assemblies of Bile Acids and Their Derivatives; Three-Axial, Tilt, Helical, and Bundle Chirality
Molecules 2007, 12, 1973-2000 (PDF format 1177 K)
(This paper belongs to Special Issue on Bile acids,edited by Dr. Erkki Kolehmainen)

Shu-Kun Lin
Molecular Diversity Preservation International (MDPI), Matthaeusstrasse 11, Basel CH-4057, Switzerland; Tel. ++41 79 322 3379, Fax: ++41 61 302 8918, E-mail: [email protected], http://www.mdpi.org/lin
Received: 20 August 2007 / Published: 22 August 2007
Editorial: Full Open Access Publishing Policy Imposed in 2007: Molecules Publishes Many More Papers This Year – More than 2000 Pages Published up to Issue 8
Molecules 2007, 12, 2001-2002 (PDF format 15 K)

Jingde Wu ¹, Xinyong Liu ^1,*, Xianchao Cheng ¹, Yuan Cao ¹, Defeng Wang ¹, Zhong Li ¹, Wenfang Xu ¹, Christophe Pannecouque ², Myriam Witvrouw ² and Erik De Clercq ²
1 Institute of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, No.44, Wenhuaxi Road, Jinan, 250012, P.R. China
2 Rega Institute for Medical Research, Katholieke Universiteit Leuven, B-3000 Leuven, Belgium; E-mail: [email protected] (Erik De Clercq)
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel: (+86)-531-88382005; Fax: (+86)-531-88382264
Received: 21 July 2007; in revised form: 17 August 2007 / Accepted: 20 August 2007 / Published: 22 August 2007
Full Paper: Synthesis of Novel Derivatives of 4-Amino-3-(2-Furyl)-5-Mercapto-1,2,4-Triazole as Potential HIV-1 NNRTIs
Molecules 2007, 12, 2003-2016 (PDF format 94 K)

Ahmed Jashari ^1,*, Evamarie Hey-Hawkins ², Bozhana Mikhova ³, Gerald Draeger ⁴ and Emil Popovski ^5,*
1 Group of Physics & Chemistry, Faculty of Natural Sciences & Mathematics, State University of Tetova, 1200 Tetova, Macedonia
2 Faculty of Chemistry and Mineralogy, University of Leipzig, Johannsallee 29, D-04103 Leipzig, Germany; E-mail: [email protected]
3 Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Akad.G.Bonchev Str. Bl.9, Sofia 1113, Bulgaria
4 Institute of Organic Chemistry, University of Hannover, D-30167, Hannover, Germany
5 Institute of Chemistry, Faculty of Natural Sciences & Mathematics, Ss. Cyril & Methodius University, PO Box 162, 1000 Skopje, Macedonia
* Authors to whom correspondence should be addressed; E-mails: [email protected]; [email protected]
Received: 3 June 2007; in revised form: 8 August 2007 / Accepted: 8 August 2007 / Published: 22 August 2007
Full Paper: An Improved Synthesis of 4-Chlorocoumarin-3-sulfonyl Chloride and Its Reactions with Different Bidentate Nucleophiles to Give Pyrido[1',2':2,3]- and Thiazino[3',2':2,3]-1,2,4-Thiadiazino[6,5-c]Benzopyran-6-one 7,7-Dioxides
Molecules 2007, 12, 2017-2028 (PDF format 77 K)

Lan-Lan Xu ¹, Kun Zou ^1,*, Jun-Zhi Wang ¹, Jun Wu ², Yuan Zhou ¹, Fei-Jun Dan ¹ and Jing Yang ¹
1 Hubei Key Laboratory of Natural Products Research and Development, College of Chemistry and Life Science, China Three Gorges University, Yichang 443002, P.R. China; E-mails: [email protected] (Lan-Lan Xu), [email protected] (Jun-Zhi Wang), [email protected], [email protected] (Fei-Jun Dan), [email protected] (Jing Yang)
2 Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, P.R. China; E-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel: (+86)-717-6392286/Fax: (+86)-717-6397478
Received: 8 June 2007; in revised form: 11 July 2007 / Accepted: 12 July 2007 / Published: 23 August 2007
Full Paper: New Polyhydroxylated Furostanol Saponins with Inhibitory Action against NO Production from Tupistra chinensis Rhizomes
Molecules 2007, 12, 2029-2037 (PDF format 137 K)

Ying Qiao, Xian-min Zhang and Ming-hua Qiu *
State Key Laboratory Phytochemistry and Plant Resource in West China, Kunming Institute of Botany, The Chinese Academy of Sciences, Kunming 650204, P.R. China; E-mails: [email protected]; [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel: (+86)871-5223327; Fax: (+86)871-5223255
Received: 17 May 2007; in revised form: 20 August 2007 / Accepted: 20 August 2007 / Published: 23 August 2007
Full Paper: Two Novel Lanostane Triterpenoids from Ganoderma Sinense
Molecules 2007, 12, 2038-2046 (PDF format 139 K)

Krittika Norajit, Natta Laohakunjit * and Orapin Kerdchoechuen *
School of Bioresources and Technology, King Mongkut’s University of Technology Thonburi, Bangkhuntein, Bangkok, Thailand 10150; E-mail: [email protected]
* Authors to whom correspondence should be addressed. Email: [email protected]; Tel.: +662 4707752; Fax: +662 4707781; Email: [email protected]; Tel./Fax +662 4707781
Received: 1 August 2007; in revised form: 20 August 2007 / Accepted: 22 August 2007 / Published: 23 August 2007
Full Paper: Antibacterial Effect of Five Zingiberaceae Essential Oils
Molecules 2007, 12, 2047-2060 (PDF format 243 K)
(This paper has been withdrawn. Editor's Note: Withdrawn Paper: Antibacterial Effect of Five Zingiberaceae Essential Oils by Laohakunjit et al., Molecules 2007, 12, 2047-2060 . Molecules 2008, 13, 588-589)

Khadijah M. Al-Zaydi * and Rita M. Borik
Department of Chemistry, Girl’s College of Education, Jeddah, P.O. 50918 Jeddah 21533, Kingdom of Saudi Arabia
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 16 February 2007; in revised form: 26 May 2007 / Accepted: 1 June 2007 / Published: 24 August 2007
Full Paper: Microwave Assisted Condensation Reactions of 2-Aryl Hydrazonopropanals with Nucleophilic Reagents and Dimethyl Acetylenedicarboxylate
Molecules 2007, 12, 2061-2079 (PDF format 125 K)

Nhuan Ngoc Doan ^1,§, Thach Ngoc Le ², Hao Cong Nguyen ³, Poul Erik Hansen ¹ and Fritz Duus ^1,*
1 Department of Science, Systems and Models, Roskilde University, P. O. Box 260, DK-4000 Roskilde, Denmark. E-mails: [email protected], [email protected]
2 Department of Organic Chemistry, University of Natural Sciences, National University of Ho Chi Minh City, 227 Nguyen Van Cu, Ho Chi Minh City, Vietnam. E-mail: [email protected]
3 Institute of Natural Products Chemistry of Ho Chi Minh City, 01 Mac Dinh Chi, Ho Chi Minh City, Vietnam. E-mail: [email protected]
§ On leave from the University of Natural Sciences, National University of Ho Chi Minh City, Vietnam
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 8 August 2007; in revised form: 23 August 2007 / Accepted: 23 August 2007 / Published: 28 August 2007
Full Paper: Ultrasound Assisted Synthesis of 5,9-Dimethylpentadecane and 5,9-Dimethylhexadecane – the Sex Pheromones of Leucoptera coffeella
Molecules 2007, 12, 2080-2088 (PDF format 62 K)

Issue 9 (September 2007) pages 2089-2269

Ricardo L. Guimarães ^1,2,†, Dimas J. P. Lima ², Maria Ester S. B. Barros ², Lívia N. Cavalcanti ², Fernando Hallwass ², Marcelo Navarro ², Lothar W. Bieber ² and Ivani Malvestiti^2,*
1 Instituto de Ciências Ambientais e Desenvolvimento Sustentável, Universidade Federal da Bahia -Campus Universitário Reitor Edgar Santos, Rua Professor José Seabra S/N - Barreiras - BA - 47805-100, Brazil; †E-mail: [email protected]
2 Departamento de Química Fundamental, Universidade Federal de Pernambuco, Cidade Universitária, Recife-PE 50670- 901, Brazil
* Author to whom correspondence should be addressed; E-mail: [email protected], [email protected]
Received: 16 June 2007; in revised form: 25 August 2007 / Accepted: 25 August 2007 / Published: 29 August 2007
Full Paper: Aqueous Barbier Allylation of Aldehydes Mediated by Tin
Molecules 2007, 12, 2089-2105 (PDF format 127 K)

Anthony P. Davis
School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK; E-mail: [email protected]
Received: 7 July 2007 / Accepted: 8 August 2007 / Published: 29 August 2007
Review: Bile Acid Scaffolds in Supramolecular Chemistry: The Interplay of Design and Synthesis
Molecules 2007, 12, 2106-2122 (PDF format 122 K)
(This paper belongs to Special Issue on Bile acids,edited by Dr. Erkki Kolehmainen)

Kai Bao ¹, Weige Zhang ^1,*, Chuanliang Zhang ¹, Yingwei Qu ¹, Liang Tian ¹, Lan Wu ², Xiang Zhao ¹ and Maosheng Cheng ^1,*
1 School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, P. R. China
2 The First Affiliated College, Chinese Medical University, Shenyang 110001, P. R. China
* Authors to whom correspondence should be addressed; E-mails: [email protected]; [email protected]
Received: 30 May 2007; in revised form 16 August 2007 / Accepted: 24 August 2007 / Published: 30 August 2007
Communication: Synthesis of Ring-Contracted Erythromycin A Derivatives via Microwave-Assisted Intramolecular Transesterification
Molecules 2007, 12, 2123-2129 (PDF format 134 K)

Mankil Jung * and Moonsoo Park
Department of Chemistry, Yonsei University, Seoul 120-749, Korea; Tel. (+82)-2123-2648; Fax. (+82)-364-7050
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 28 November 2006; in revised form: 21 August 2007 / Accepted: 21 August 2007 / Published: 3 September 2007
Full Paper: Acetylcholinesterase Inhibition by Flavonoids from Agrimonia pilosa
Molecules 2007, 12, 2130-2139 (PDF format 293 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Jun Lei ¹, Xiang Li ^1,†, Xiao-jie Gong ² and Yi-nan Zheng ^1,*
1 College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, P. R. China; † E-mail: [email protected]
2 Pharmaceutical College, Dalian University, Dalian 116622, P. R. China
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel.: +86-431-8453-3306, Fax: +86-431-8451-5607
Received: 30 July 2007; in revised form: 24 August 2007 / Accepted: 26 August 2007 / Published: 5 September 2007
Full Paper: Isolation, Synthesis and Structures of Cytotoxic Ginsenoside Derivatives
Molecules 2007, 12, 2140-2150 (PDF format 90 K)

Zuhal Turgut *, Cigdem Yolacan, Feray Aydogan, Emine Bagdatli and Nuket Ocal
Yildiz Technical University, Faculty of Arts and Sciences, Department of Chemistry, Davutpasa Campus, Esenler, 34210, Istanbul, Turkey
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 11 August 2007; in revised form: 2 September 2007 / Accepted: 3 September 2007 / Published: 6 September 2007
Full Paper: Synthesis of New Pyrazolothiazole Derivatives from 4-Thiazolidinones
Molecules 2007, 12, 2151-2159 (PDF format 70 K)

Editorial Note: Withdrawn Paper: Li, M. D.; Zheng, Y. G.; Ji, M. Synthesis of Gefitinib from Methyl 3-Hydroxy-4-methoxybenzoate. Molecules 2007, 12, 673-678
Molecules 2007, 12, 2160 (PDF format 14 K)

Arto Valkonen*, Erkki Kolehmainen, Manu Lahtinen, Elina Sievänen, Virpi Noponen, Minna Tolonen and Reijo Kauppinen
Department of Chemistry, University of Jyväskylä, PO. Box 35, FIN-40014 University of Jyväskylä, Finland
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 17 August 2007; in revised form: 9 September 2007/ Accepted: 12 September 2007 / Published: 12 September 2007
Full Paper: Structural, Thermoanalytical and Molecular Modeling Studies on N-(3-hydroxypropyl) 3α,12α-Dihydroxy-5β-cholan-24-amide and Its Monohydrates
Molecules 2007, 12, 2161-2178 (PDF format 356 K)
(This paper belongs to Special Issue on Bile acids, edited by Dr. Erkki Kolehmainen)

Jose M. Bueno
R&D Manager, Hausmann S.A., San Andrés de la Barca, 08740, Barcelona, Spain; E-mail: [email protected]
Critique: Comments on “Antibacterial Effect of Five Zingiberaceae Essential Oils” by Laohakunjit et al., Molecules 2007, 12, 2047-2060
Molecules 2007, 12, 2179-2180 (PDF format 28 K)

(open access to this paper was granted by MDPI )
Shreedhar Bhat ¹ and Uday Maitra ^1,2,*
1 Department of Organic Chemistry, Indian Institute of Science, Bangalore, India 560012
2 Chemical Biology Units, JNCASR, Bangalore, India, 560012
* Author to whom correspondence should be addressed; E-mail: [email protected].
Received: 8 August 2007 / Accepted: 17 September 2007 / Published: 18 September 2007
Full Paper: Hydrogels as Reaction Vessels: Acenaphthylene Dimerization in Hydrogels Derived from Bile Acid Analogues
Molecules 2007, 12, 2181-2189 (PDF format 109 K)
(This paper belongs to Special Issue on Bile acids,edited by Dr. Erkki Kolehmainen)

Shu-Kun Lin and Derek J. McPhee
Molecular Diversity Preservation International (MDPI), Matthaeusstrasse 11, Basel CH-4057, Switzerland; Tel. ++41 79 322 3379, Fax: ++41 61 302 8918, E-mails: [email protected], [email protected]; http://www.mdpi.org/lin
Received: 16 September 2007 / Published: 19 September 2007
Editorial: Citation of Two Retracted Papers Shows Both the Impact Advantage and an Unintended Consequence of Open Access
Molecules 2007, 12, 2190-2192 (PDF format 29 K)

Rajesh Kumar, Arvind K. Gupta and Mahabir P. Kaushik*
Process Technology Development Division, Defence R & D Establishment, Jhansi Road, Gwalior-474002 (MP), India. Tel. +91-751-2343972, Fax +91-751-2341148
* Author to whom correspondence should be addressed; e-mail: [email protected]
Received: 15 August 2007; in revised form: 20 September 2007 / Accepted: 20 September 2007 / Published: 21 September 2007
Full Paper: Novel and Efficient Synthesis of N,N-dialkylamino-O-alkyl-2-(1-methyl-2-oxopropylidene)phosphorohydrazido Oximes. Part 3.
Molecules 2007, 12, 2193-2200 (PDF format 55 K)

Rosa María Claramunt ^1,*, Dolores Santa María ¹, Elena Pinilla ², M. Rosario Torres² and José Elguero ³
1 Departamento de Química Orgánica y Bio-Orgánica, Facultad de Ciencias, UNED, Senda del Rey 9, 28040 Madrid, Spain
2 Departamento de Química Inorgánica I, Facultad de Ciencias Químicas, Universidad Complutense de Madrid (UCM), 28040 Madrid, Spain
3 Instituto de Química Médica, Consejo Superior de Investigaciones Científicas (CSIC), Juan de la Cierva 3, 28006 Madrid, Spain
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel: (+34) 91 3987322; Fax: (+34) 91 3988372
Received: 11 September 2007; in revised form: 20 September 2007 / Accepted: 20 September 2007 / Published: 21 September 2007
Full Paper: Structural Studies of Two Tinuvin^® P Analogs: 2-(2,4-Dimethyl-phenyl)-2H-benzotriazole and 2-Phenyl-2H-benzotriazole
Molecules 2007, 12, 2201-2214 (PDF format 242 K)

(open access to this paper was granted by MDPI )
Guy L. Plourde*, Randy R. Spaetzel, Jolene S. Kwasnitza and Thomas W. Scully
University of Northern British Columbia, Department of Chemistry, 3333 University Way, Prince George, British Columbia, Canada, V2N 4Z9; Tel: +1-250-960-6694, Fax: +1-250-960-5845
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 7 September 2007; in revised form: 24 September 2007 / Accepted: 24 September 2007 / Published: 25 September 2007
Full Paper: Diastereoselective Spiroannulation of Phenolic Substrates: Advances Towards the Asymmetric Formation of the Manumycin m-C₇N Core Skeleton
Molecules 2007, 12, 2215-2222 (PDF format 54 K)

Rahim Hekmatshoar ^1,*, Sodeh Sajadi ¹, Majid M. Heravi ¹ and Fatemeh F. Bamoharram ²
1 Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran, Iran; E-mails: [email protected]; [email protected]
2 Department of Chemistry, School of Sciences, Azad University, Khorasan Branch, Mashad, Iran; E-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel.:(+98)-21-88044040; Fax: (+98)-21-88035187
Received: 12 June 2007; in revised form: 15 September 2007 / Accepted: 16 September 2007 / Published: 25 September 2007
Communication: H₁₄[NaP₅W₃₀O₁₁₀] as a Heterogeneous Recyclable Catalyst for the Air Oxidation of Thiols Under Solvent Free Conditions
Molecules 2007, 12, 2223-2228 (PDF format 75 K)

Nour-Eddine Es-Safi ^1,2,*, Souhila Ghidouche ¹ and Paul Henri Ducrot ^1,*
1 Unité de Phytopharmacie et Médiateurs Chimiques, INRA, Route de Saint-Cyr, 78026 Versailles Cedex, France; E-mails: [email protected] (Guidouche); [email protected] (Ducrot)
2 Laboratoire de Chimie Organique et d’Etudes Physico-Chimiques, Pôle de Compétences Pharmacochimie. Ecole Normale Supérieure, B.P 5118 Takaddoum Rabat, Morocco
* Authors to whom correspondence should be addressed; E-mails: [email protected] (Es-Safi); [email protected] (Ducrot)
Received: 29 May 2007; in revised form: 17 September 2007 / Accepted: 18 September 2007 / Published: 26 September 2007
Review: Flavonoids: Hemisynthesis, Reactivity, Characterization and Free Radical Scavenging Activity
Molecules 2007, 12, 2228-2258 (PDF format 532 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Aphrodite-Victoria Sakkiadi, Constantinos A. Georgiou and Serkos A. Haroutounian*
Chemistry Laboratory, Agricultural University of Athens, Iera odos 75, Athens 11855, Greece
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 19 September 2007; in revised form: 26 September 2007 / Accepted: 26 September 2007 / Published: 27 September 2007
Full Paper: A Standard Addition Method to Assay the Concentration of Biologically Interesting Polyphenols in Grape Berries by Reversed-Phase HPLC
Molecules 2007, 12, 2259-2269 (PDF format 91 K)

Issue 10 (October 2007) pages 2270-2433

Min Cheol Yang, Sung Min Kim, Kyu Ha Lee, Ki Hyun Kim and Kang Ro Lee*
Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University, Suwon 440-746, Korea
* To whom correspondence should be addressed; [email protected]; Fax. (+82)-31-292-8800
Received: 17 September 2007; in revised form: 1 October 2007 / Accepted: 1 October 2007 / Published: 2 October 2007
Communication: A New Sesquiterpene Glycoside from the Aerial Parts of Saussurea triangulata
Molecules 2007, 12, 2270-2276 (PDF format 117 K)

Editorial Note: Notice of Dual Publication: Madkour*, H.M.F.; Mahmoud, M.R.; Nassar, M.H.; Habashy, M.M. Behaviour of Some Activated Nitriles Toward Barbituric Acid, Thiobarbituric Acid and 3-Methyl-1-Phenylpyrazol-5-one. Molecules 2000, 5, 746-755
Molecules 2007, 12, 2277-2278 (PDF format 15 K)
("WITHDRAWN" watermark has been added to the original paper at http://www.mdpi.org/molecules/papers/50500746.pdf)

Angela Bisio ¹, Bruno Pagano ², Alessia Romussi ³, Olga Bruno ³, Nunziatina De Tommasi ², Giovanni Romussi ¹ and Carlo Andrea Mattia ^2,*
1 Dipartimento di Chimica e Tecnologie Farmaceutiche e Alimentari, Università di Genova, Via Brigata Salerno, Genova, Italy
2 Dipartimento di Scienze Farmaceutiche, Università di Salerno, Via Ponte Don Melillo, 84084 Fisciano, Salerno, Italy
3 Dipartimento di Scienze Farmaceutiche, Università di Genova, Viale Benedetto XV, Genova, Italy
* Author to whom correspondence should be addressed. E-mail: [email protected] Tel.: +39 089 969759, Fax: +39 089 969602
Received: 27 September 2007; in revised form: 5 October 2007 / Accepted: 5 October 2007 / Published: 10 October 2007
Full Paper: Relative Stereochemistry of a Diterpene from Salvia cinnabarina
Molecules 2007, 12, 2279-2287 (PDF format 148 K)

Bhuwan B. Mishra ¹, S. B. Yadav ¹, Rakesh K. Singh ² and Vyasji Tripathi ^1,*
1 Department of Chemistry, Faculty of Science, Banaras Hindu University, Varanasi-221005, India; E-mails: [email protected]; [email protected]
2 Department of Biochemistry, Faculty of Science, Banaras Hindu University, Varanasi-221005, India; Email: [email protected]
* Author to whom correspondence should be addressed. E-mail: [email protected] Tel: (+91) 9415343791 Fax: 91-542-2368174
Received: 30 July 2007; in revised form: 11 September 2007 / Accepted: 11 September 2007 / Published: 20 October 2007
Communication: A Novel Flavonoid C-glycoside from Sphaeranthus indicus L. (Family Compositae)
Molecules 2007, 12, 2288-2291 (PDF format 43 K)

Patrick Garidel, Annegret Hildebrand, Katja Knauf and Alfred Blume*
Martin-Luther-University Halle-Wittenberg, Institute of Chemistry, Physical Chemistry, Muehlpforte 1, D-06108 Halle/Saale, Germany
* Author to whom correspondence should be addressed: [email protected]
Received: 9 September 2007; in revised form: 15 October 2007 / Accepted: 15 October 2007 / Published: 23 October 2007
Full Paper: Membranolytic Activity of Bile Salts: Influence of Biological Membrane Properties and Composition
Molecules 2007, 12, 2292-2326 (PDF format 1264 K)
(This paper belongs to Special Issue on Bile acids,edited by Dr. Erkki Kolehmainen)

Aleksandra Simić, Dragan Manojlović *, Dejan Šegan and Marija Todorović
Faculty of Chemistry, University of Belgrade, Studentski trg 12-16, 11000 Belgrade, Serbia; E-mails: [email protected], [email protected], [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 15 June 2007; in revised form: 4 October 2007 / Accepted: 4 October 2007 / Published: 24 October 2007
Full Paper: Electrochemical Behavior and Antioxidant and Prooxidant Activity of Natural Phenolics
Molecules 2007, 12, 2327-2340 (PDF format 130 K)
(This paper belongs to Special Issue on Phenolics (flavonoids and non-flavonoids))

Kamil Kuca ^1,2,3, Jan Marek ^4,5, Petr Stodulka ¹, Kamil Musilek ^2,5,*, Petra Hanusova ⁴, Martina Hrabinova ¹ and Daniel Jun ^1,2
1 Center of Advanced Studies, Faculty of Military Health Sciences, Hradec Kralove, Czech Republic
2 Department of Toxicology, Faculty of Military Health Sciences, Hradec Kralove, Czech Republic
3 Department of Chemistry, Faculty of Sciences, J.E. Purkinje University, Usti nad Labem, Czech Republic
4 Vakos XT, Prague, Czech Republic
5 Faculty of Pharmacy in Hradec Kralove, Charles University in Prague, Hradec Kralove, Czech Republic
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 3 September 2007; in revised form 3 October 2007 / Accepted: 4 October 2007 / Published: 24 October 2007
Communication: Preparation of Benzalkonium Salts Differing in the Length of a Side Alkyl Chain
Molecules 2007, 12, 2341-2347 (PDF format 57 K)

Muhammad Sheeraz Ahmad ¹, Mukhtiar Hussain ², Muhammad Hanif ², Saqib Ali 2 and Bushra Mirza ^1,*
1 Department of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad Pakistan; E-mail: [email protected] (Muhammad Sheeraz Ahmad)
2 Department of Chemistry, Quaid-i-Azam University, Islamabad-45320, Pakistan
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 17 July 2007; in revised form: 9 August 2007 / Accepted: 10 August / Published: 25 October 2007
Full Paper: Synthesis, Chemical Characterization and Biological Screening for Cytotoxicity and Antitumor Activity of Organotin (IV)
Derivatives of 3,4-Methylenedioxy 6-nitrophenylpropenoic Acid
Molecules 2007, 12, 2348-2363 (PDF format 96 K)

Aliasghar Jarrahpour * and Maaroof Zarei
Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran; Tel.: +98 711 2284822; fax: +98 711 2280926
* Author to whom correspondence should be addressed; E-mails: ([email protected] or [email protected])
Received: 20 June 2007; in revised form: 26 August 2007 / Accepted: 26 August 2007 / Published: 25 October 2007
Full Paper: Synthesis of Novel N-(4-Ethoxyphenyl) Azetidin-2-ones and Their Oxidative N-Deprotection by Ceric Ammonium Nitrate
Molecules 2007, 12, 2364-2379 (PDF format 99 K)

Jesper Østergaard* and Claus Larsen^†
Department of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen O, Denmark; †E-mail: [email protected]
* Author to whom correspondence should be addressed. E-mail: [email protected]
Received: 28 September 2007; in revised form: 29 October 2007 / Accepted: 29 October 2007 / Published: 30 October 2007
Full Paper: Bioreversible Derivatives of Phenol. 1. The Role of Human Serum Albumin as Related to the Stability and Binding Properties of Carbonate Esters with Fatty Acid-like Structures in Aqueous Solution and Biological Media
Molecules 2007, 12, 2380-2395 (PDF format 107 K)
(This paper belongs to Special Issue on Prodrugs: from Design to Applications. Guest Editor: Dr. Jean Jacques Vanden Eynde)

Jesper Østergaard* and Claus Larsen^†
Department of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen O, Denmark; †E-mail: [email protected]
* Author to whom correspondence should be addressed. E-mail: [email protected]
Received: 28 September 2007; in revised form: 29 October 2007 / Accepted: 29 October 2007 / Published: 30 October 2007
Full Paper: Bioreversible Derivatives of Phenol. 2. Reactivity of Carbonate Esters with Fatty Acid-like Structures Towards Hydrolysis in Aqueous Solutions
Molecules 2007, 12, 2396-2412 (PDF format 156 K)
(This paper belongs to Special Issue on Prodrugs: from Design to Applications. Guest Editor: Dr. Jean Jacques Vanden Eynde)

Ashis Kumar Nanda ^1,*, Subarna Ganguli ² and Ranadhir Chakraborty ³
1 Department of Chemistry, North Bengal University, Raja Rammohunpur, Siliguri, 734013, WB, India
2 Himalayan Pharmacy Institute, Majhitar, P.O.Rangpo, E.Sikkim, 737132, India; E-mail: [email protected]
3 Department of Biotechnology, North Bengal University, Raja Rammohunpur, Siliguri, 734013, WB, India; E-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel.: (+91)-0353-2699425, (+91)9474329191; Fax: (+91)-0353-2581212
Received: 7 August 2007; in revised form: 9 October 2007 / Accepted: 9 October 2007 / Published: 30 October 2007
Full Paper: Antibacterial Activity of Some 3-(Arylideneamino)-2-phenylquinazoline-4(3H)-ones: Synthesis and Preliminary QSAR Studies
Molecules 2007, 12, 2413-2426 (PDF format 151 K)

Mehdi Ghandi * and Gholamreza Mashayekhi
School of Chemistry, University College of Science, University of Tehran, Tehran, Iran
* PAuthor to whom correspondence should be addressed; E-mail: [email protected];
Tel.: (+98)-21-61112250; Fax: (+98)-21-66495291
Received: 4 August 2007; in revised form: 19 October 2007/ Accepted: 20 October 2007 / Published: 30 October 2007
Full Paper: A Simple and Efficient Approach to the Synthesis of Endo and Exo Bicyclo[6.1.0]nona-3,5-diene-9-carboxaldehyde
Molecules 2007, 12, 2427-2433 (PDF format 91 K)

Issue 11 (November 2007) pages 2434-2566

Piotr Luliński ¹, Dorota Maciejewska ^1,*, Magdalena Bamburowicz-Klimkowska ² and Mirosław Szutowski ²
1 Department of Organic Chemistry, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1 Str., 02-097 Warsaw, Poland
2 Department of Toxicology, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1 Str., 02-097 Warsaw, Poland
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel:(+48) 225720643; Fax: (+48) 225720643.
Received: 21 August 2007; in revised form: 9 October 2007 / Accepted: 21 October 2007 / Published: 1 November 2007
Full Paper: Dopamine-Imprinted Polymers: Template-Monomer Interactions, Analysis of Template Removal and Application to Solid Phase Extraction
Molecules 2007, 12, 2434-2449 (PDF format 166 K)

Zhi-Yong Tian ^1,2, Gang-Jun Du 2, Song-Qiang Xie ², Jin Zhao ³, Wen-Yuan Gao ^1,* and Chao-Jie Wang ^3,*
1 School of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Nankai District, 300072, Tianjin, P. R. China; Phone: (+86) 22-87401895; E-mail: [email protected],
2 College of Pharmaceutical Science, Henan University, Jinming District, 475001, Kaifeng, Henan, P. R. China; Phone: (+86) 0378-3880660; E-mail: [email protected]
3 Institute of Natural Products and Medicinal Chemistry, College of Chemistry and Chemical Engineering, Henan University, Jinming District, 475001, Kaifeng, Henan, P. R. China
* Authors to whom correspondence should be addressed; E-mail: [email protected]; Phone: (+86) 22-87401895; E-mail: [email protected]; Cell Phone: (+86) 13619810550
Received: 9 August 2007; in revised form: 9 October 2007 / Accepted: 9 October 2007 / Published: 6 November 2007
Full Paper: Synthesis and Bioevaluation of 5-Fluorouracil Derivatives
Molecules 2007, 12, 2450-2457 (PDF format 82 K)

Shive Murat Singh Chauhan*, Bhaskar Garg and Tanuja Bisht
Bioorganic Research Laboratory, Department of Chemistry, University of Delhi, Delhi-110007, India; Fax : (+91)-11-27666845
* Author to whom correspondence should be addressed. E-mail: [email protected]
Received: 1 October 2007; in revised form: 1 November 2007 / Accepted: 1 November 2007 / Published: 9 November 2007
Full Paper: Syntheses of Calix[4]Pyrroles by Amberlyst-15 Catalyzed Cyclocondensations of Pyrrole with Selected Ketones
Molecules 2007, 12, 2458-2466 (PDF format 62 K)

Ameya A. Chavan and Nandini R. Pai *
Department of Organic Chemistry, D.G.Ruparel College, Senapati Bapat Marg, Mahim, Mumbai-400016, India. Tel: (+91) 022 24303733; Fax: (+91) 022 24303042.
* Author to whom correspondence should be addressed; E-mails: [email protected] or [email protected]
Received: 31 July 2007; in revised form: 22 October 2007 / Accepted: 31 October 2007 / Published: 12 November 2007
Full Paper: Synthesis and Biological Activity of N-Substituted-3-chloro-2-azetidinones
Molecules 2007, 12, 2467-2477 (PDF format 62 K)

Hamdi Özkan ¹, Ali Dişli ¹, Yılmaz Yıldırır ^1,* and Lemi Türker ²
1 Department of Chemistry, Faculty of Science and Arts, Gazi University, Teknikokullar, 06500 Ankara, Turkey; E-mails: [email protected]; [email protected]
2 Department of Chemistry, Middle East Technical University, 06531 Ankara, Turkey; E-mail: [email protected]
* Author to whom correspondence should be addressed. E-mail: [email protected]; Tel: (+90) 312 202 11 02
Received: 19 October 2007; in revised form: 6 November 2007 / Accepted: 6 November 2007 / Published: 12 November 2007
Communication: A Novel Synthesis of Bromobenzenes Using Molecular Bromine
Molecules 2007, 12, 2478-2483 (PDF format 58 K)

Paula Gomes ^1,*, Nuno Vale ¹ and Rui Moreira ²
1 Centro de Investigação em Química da Universidade do Porto, Departamento de Química, Faculdade de Ciências, Universidade do Porto, Porto, Portugal
2 Centro de Estudos de Ciências Farmacêuticas, Faculdade de Farmácia, Universidade de Lisboa, Lisboa, Portugal
* Corresponding author: R. Campo Alegre 687, P-4169-007 Porto, Portugal; Phone: + 351220402563; Fax: +351 220402659; E-mail: [email protected]
Received: 6 October 2007; in revised form: 8 November 2007 / Accepted: 9 November 2007 / Published: 12 November 2007
Review: Cyclization-activated Prodrugs
Molecules 2007, 12, 2484-2506 (PDF format 158 K)
(This paper belongs to Special Issue on Prodrugs: from Design to Applications. Guest Editor: Dr. Jean Jacques Vanden Eynde)

Yun-Yan Kuang † and Fen-Er Chen *
Department of Chemistry, Fudan University, Shanghai 200433, People’s Republic of China; † e-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 24 May 2007; in revised form: 6 August 2007 / Accepted: 6 August 2007 / Published: 13 November 2007
Full Paper: Synthesis and Molecular Structure of Ethyl [N-tosyl-(R)-prolyloxy]-2(S)-[4-cyano-8,8-ethylenedioxy-5-oxo-5,6,7,8-tetrahydroindolizin-3-yl] Acetate, a Key Intermediate in the Total Synthesis of (20S)-Camptothecins
Molecules 2007, 12, 2507-2514 (PDF format 122 K)

Guillermo Negrón-Silva ^1,*, C. Xochitl Hernández-Reyes ¹, Deyanira Angeles-Beltrán ¹, Leticia Lomas-Romero ², Eduardo González-Zamora ² and Juan Méndez-Vivar ²
1 Departamento de Ciencias Básicas and
2 Departamento de Química, UAM, Av. San Pablo No 180. C. P. 02200, México D. F., México; E-mail addresses: C. Xochitl Hernández: [email protected], Deyanira Angeles-Beltrán: [email protected], Leticia Lomas-Romero: [email protected], Eduardo González-Zamora: [email protected], Juan Méndez-Vivar: [email protected].
* Author to whom correspondence should be addressed. e-mail: [email protected]
Received: 29 September 2007 / Accepted: 13 November 2007 / Published: 15 November 2007
Full Research Paper: Comparative Study of Regioselective Synthesis of β-Aminoalcohols under Solventless Conditions Catalyzed by Sulfated Zirconia and SZ/MCM-41
Molecules 2007, 12, 2515-2532 (PDF format 454 K)

Anne Sophie Voisin-Chiret, Marc-Antoine Bazin, Jean-Charles Lancelot and Sylvain Rault *
Université de Caen Basse-Normandie, U.F.R. des Sciences Pharmaceutiques, Centre d’Etudes et de Recherche sur le Médicament de Normandie, UPRES EA-3915, 5, rue Vaubénard, 14032 CAEN Cedex, France
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel: +33 (0)2 31 93 64 58; Fax: +33 (0)2 31 93 11 88.
Received: 30 October 2007; in revised form: 15 November 2007 / Accepted: 15 November 2007 / Published: 17 November 2007
Full Paper: Synthesis of New L-Ascorbic Ferulic Acid Hybrids
Molecules 2007, 12, 2533-2545 (PDF format 454 K)

Mirela Filipan-Litvić ¹, Mladen Litvić ^1,*, Ivica Cepanec ¹ and Vladimir Vinković ²
1 BELUPO Pharmaceuticals, Inc. R&D, Danica 5, 48000 Koprivnica, Croatia; E-mail: [email protected]; E-mail: [email protected]
2 Institute Ruđer Bošković, Bijenička c. 54, 10002 Zagreb, Croatia; E-mail: [email protected]
* Author to whom correspondence should be addressed. E-mail: [email protected]; Tel: (+385) 48 652 458; Fax: (+385) 48 652 461.
Received: 9 November 2007; in revised form: 22 November 2007 / Accepted: 23 November 2007 / Published: 26 November 2007
Full Paper: Hantzsch Synthesis of 2,6-Dimethyl-3,5-dimethoxycarbonyl-4-(o-methoxyphenyl)-1,4-dihydropyridine; a Novel Cyclisation Leading to an Unusual Formation of 1-Amino-2-methoxycarbonyl-3,5-bis(o-methoxyphenyl)-4-oxa-cyclohexan-1-ene
Molecules 2007, 12, 2546-2558 (PDF format 97 K)

Yoshifumi Murata ^1,*, Daisaku Jinno ¹, Dongchun Liu ², Takshi Isobe ¹, Kyouko Kofuji ¹ and Susumu Kawashima ¹
1 Faculty of Pharmaceutical Science, Hokuriku University, Ho-3, Kanagawa-machi, Kanazawa 920-1181, Japan
2 Department of Pharmacognosy, Shenyang Pharmaceutical University, Wen Hua Road 103, mailbox 48, Shenhe, Shenyang, 110016, PRC
* Author to whom correspondence should be addressed; E-mail: [email protected]; Phone: +81-076-229-6184; Fax: +81-076-229-2781
Received: 17 November 2007; in revised form: 27 November / Accepted: 27 November 2007 / Published: 29 November 2007
Full Paper: The Drug Release Profile from Calcium-induced Alginate Gel Beads Coated with an Alginate Hydrolysate
Molecules 2007, 12, 2559-2566 (PDF format 109 K)
(This paper belongs to Special Issue on Prodrugs: from Design to Applications. Guest Editor: Dr. Jean Jacques Vanden Eynde)

Issue 12 (Deceember 2007) pages 2567-2657

Antonios Michaelakis 1, Spiridon A. Theotokatos ², Georgios Koliopoulos ¹ and Nikos G. Chorianopoulos ^3,*
1 Benaki Phytopathological Institute, 8 S. Delta Str. 14561 Kifissia, Athens, Greece
2 Agroindustrial Robola Growers Cooperative of Kefalllinia, Omala, 28100 Kefallinia, Greece
3 Chemistry Laboratory, Agricultural University of Athens, Iera odos 75, Athens, 11855, Greece
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 9 November 2007; in revised form: 7 December 2007 / Accepted: 7 December 2007 / Published: 10 December 2007
Full Paper: Essential Oils of Satureja Species: Insecticidal Effect on Culex pipiens Larvae (Diptera: Culicidae)
Molecules 2007, 12, 2567-2578 (PDF format 109 K)

Ebru Mete ¹, Halise Inci Gul ^2,* and Cavit Kazaz ¹
1 Department of Chemistry, Faculty of Arts and Sciences, Ataturk University, 25240, Erzurum, Turkey
2 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ataturk University, 25240, Erzurum, Turkey
* Author to whom correspondence should be addressed; E-mail: [email protected] or [email protected]; Tel: +90-442-2311539; Fax: +90-442-2360962
Received: 29 October 2007; in revised form: 26 November 2007 / Accepted: 10 December 2007 / Published: 12 December 2007
Full Paper: Synthesis of 1-Aryl-3-phenethylamino-1-propanone Hydrochlorides as Possible Potent Cytotoxic Agents
Molecules 2007, 12, 2579-2588 (PDF format 80 K)
(This paper belongs to Special Issue on Prodrugs: from Design to Applications. Guest Editor: Dr. Jean Jacques Vanden Eynde)

Martin Doležal ^1,*, Lenka Tůmová ², Diana Kešetovičová 1, Jiří Tůma ³ and Katarína Kráľová ⁴
1 Department of Pharmaceutical Chemistry and Drug Control, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Heyrovského 1203, Hradec Králové, 500 05, Czech Republic; E-mail: [email protected]
2 Department of Pharmacognosy, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Heyrovského 1203, Hradec Králové, 500 05, Czech Republic; E-mail: [email protected]
3 Department of Biology, Faculty of Education, University of Hradec Kralove, Víta Nejedlého 573 Hradec Králové, 500 03, Czech Republic; E-mail: [email protected]
4 Institute of Chemistry, Faculty of Natural Sciences, Comenius University, Mlynská Dolina CH-2, 842 15 Bratislava, Slovak Republic; E-mail: [email protected]
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 27 November 2007; in revised form: 14 December 2007 / Accepted: 14 December 2007 / Published: 20 December 2007
Full Paper: Substituted N-Phenylpyrazine-2-carboxamides, Their Synthesis and Evaluation as Herbicides and Abiotic Elicitors
Molecules 2007, 12, 2589-2598 (PDF format 86 K)

Yaling Song ^1,3, Yuehu Wang ¹, Qing Lu ¹, Jinming Gao ³, Minggang Bi ^2,* and Yongxian Cheng ^1,*
1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P. R. China
2 Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing 100094, P. R. China
3 College of Sciences, Northwest A & F University, Yangling 712100, P. R. China
* Authors to whom correspondence should be addressed. E-mail: [email protected] (Y. X. Cheng) or [email protected] (M. G. Bi)
Received: 24 November 2007; in revised form: 11 December 2007 / Accepted: 11 December 2007 / Published: 20 December 2007
Full Paper: Two New Triterpenoids from Photinia serrulata
Molecules 2007, 12, 2599-2604 (PDF format 60 K)

Luis Espinoza Catalán ^1,*, Karen Catalán Marín ¹, Héctor Carrasco Altamirano ², Mauricio Cuellar Fritis ³ and María Cristina Chamy ²
1 Departamento de Química, Universidad Técnica Federico Santa María, Av. España N° 1680, Valparaíso, Chile
2 Departamento de Ciencias Químicas, Universidad Andrés Bello, Campus Viña del Mar, Los Fresnos N° 52, Viña del Mar, Chile
3 Facultad de Farmacia, Universidad de Valparaíso, Av. Gran Bretaña N° 1093, Valparaíso, Chile
* Author to whom correspondence should be addressed; E-mail: [email protected]. For part I, see reference 19.
Received: 30 October 2007; in revised form: 17 December 2007 / 21 December 2007
Full Paper: Oxidative Degradations of the Side Chain of Unsaturated Ent-labdanes. Part II
Molecules 2007, 12, 2605-2620 (PDF format 142 K)

Xingwen Gao, Xuejian Cai, Kai Yan, Baoan Song*, Lili Gao and Zhuo Chen
Center for Research and Development of Fine Chemicals, Guizhou University, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guiyang, 550025, P. R.
China. E-mails: [email protected]; [email protected]; [email protected]; [email protected]; gychenzhuo@yahoo. com.cn
* Author to whom correspondence should be addressed; E-mail: [email protected]; Tel.:(+86) 851 3620521, Fax: (+86) 851 3622211.
Received: 8 November 2007; in revised form: 17 December 2007 / Accepted: 25 December 2007 / Published: 27 December 2007
Full Paper: Synthesis and Antiviral Bioactivities of 2-Aryl- or 2-Methyl-3-(substituted- Benzalamino)-4(3H)-quinazolinone Derivatives
Molecules 2007, 12, 2621-2642 (PDF format 352 K)

Franciszek Herold ^1,*, Małgorzata Kałucka ¹, Marek Król ¹, Joanna Herold ², Jerzy Kleps ¹ and Jadwiga Turło ¹
1 Department of Drug Technology, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1 Str., 02-097 Warsaw, Poland
2 Department of Drug Chemistry, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1 Str., 02-097 Warsaw, Poland
* Author to whom correspondence should be addressed; E-mail: [email protected]
Received: 6 December 2007; in revised form: 21 December 2007 / Accepted: 21 December 2007/ Published: 30 December 2007
Full Paper: Synthesis of a New Scaffold: the 7H,8H-Pyrimido[1,6-b]pyridazin-6,8-dione Nucleus
Molecules 2007, 12, 2643-2657 (PDF format 114 K)

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