Dusan Sladic ^1,* and Miroslav J. Gasic ^2,*
1 Faculty of Chemistry, University of Belgrade, Studentski trg 12-16, POB 158, 11001 Belgrade, Serbia and Montenegro, Tel. +381-64-2795778; Fax. +381-11-636061
2 IHTM Department of Chemistry, University of Belgrade, Studentski trg 12-16, POB 473, 11001 Belgrade, Serbia and Montenegro
* Authors to whom correspondence should be addressed; e-mails: dsladic@chem.bg.ac.yu; mjgasic@chem.bg.ac.yu
Review: Reactivity and Biological Activity of the Marine Sesquiterpene Hydroquinone Avarol and Related Compounds from Sponges of the Order Dictyoceratida
Molecules 2006, 11, 1–33 (PDF format 367 K)


Jiri Verner and Milan Potacek*
Department of Organic Chemistry, Faculty of Science, Masaryk University Brno, Kotlarska 2, 611 37 Brno, Czech Republic. Tel. (+420)-549496615, Fax (+420)-549492688.
* Author to whom correspondence should be addressed
Criss-cross Cycloadditions on Ketazines Derived from Alicyclic Ketones
Molecules 2006, 11, 34–42 (PDF format 172 K)


Om Prakash *, Kamaljeet Pannu and Ajay Kumar
Department of Chemistry, Kurukshetra University, Kurukshetra, Haryana 136 119, India
* Author to whom correspondence should be addressed; Fax: (+91) 1744 238277; e-mail: dromprakash50@rediffmail.com
Synthesis of Some New 2-(3-Aryl-1-phenyl-4-pyrazolyl)-benzoxazoles Using Hypervalent Iodine Mediated Oxidative Cyclization of Schiff’s Bases
Molecules 2006, 11, 43-48 (PDF format 53 K)


Aliasghar Jarrahpour * and Maaroof Zarei
Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran
* Author to whom correspondence should be addressed; Tel.: (+98) 711 2284822; Fax: (+98) 711 2280926; e-mail: jarrah@susc.ac.ir or aliasghar6683@yahoo.com
Synthesis of Novel N-Sulfonyl Monocyclic β-Lactams as Potential Antibacterial Agents
Molecules 2006, 11, 49-58 (PDF format 225 K)


A. A. Jarrahpour* and D. Khalili
Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran
Tel.: +98 711 228 4822Fax: +98 711 228 0926.
*Author to whom correspondence should be addressed; E-mail: aliasghar6683@yahoo.com & jarrah@susc.ac.ir
Synthesis of Some New bis-Schiff Bases of Isatin and 5-Fluoroisatin in a Water Suspension Medium
Molecules 2006, 11, 59–63 (PDF format 106 K)

(open access to this paper was granted by MDPI after delay)   
Vytautas Getautis*, Maryte Daskeviciene, Tadas Malinauskas, Albina Stanisauskaite and Jolanta Stumbraite
Department of Organic Chemistry, Kaunas University of Technology, LT-50270 Kaunas, Lithuania Tel. (370)-37-300196, Fax (370)-37-300152
* Author to whom correspondence should be addressed
An Efficient Scalable Synthesis of 2,3-Epoxypropyl Phenylhydrazones
Molecules 2006, 11, 64-71 (PDF format 135 K)


Birute Sapijanskaite ¹, Vytautas Mickevicius ^1,† and Gema Mikulskiene  ^2,*
1 Department of Organic Chemistry, Kaunas University of Technology, Radvilenu pl. 19, LT-50254 Kaunas, Lithuania, Tel.: (+370) 37 456 561, Fax: (+370) 37 300 152, † Email: vytautas.mickevicius@ktu.lt
2 Institute of Biochemistry, LT-08662 Vilnius, Mokslininku 12, Lithuania, Tel.: (+370) 5 272 9195, Fax: (+370) 5 272 9196
*Author to whom correspondence should be addressed; E-mail: gemam@bchi.lt
Reactions of 9-Alkyl-3-aminocarbazoles with Ethyl-3-oxo-butanoate and Identification of the Products Obtained
Molecules 2006, 11, 72–80 (PDF format 85 K)

Carlos A. M. Afonso ^1,*, Nuno M. T. Lourenco ² and Andreia de A. Rosatella ²

1 CQFM, Departamento de Engenharia Química, Instituto Superior Técnico, 1049-001 Lisboa, Portugal; Fax + 351 21 8464455.
2 REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal.
* Author to whom correspondence should be addressed; e-mail: carlosafonso@ist.utl.pt
Synthesis of 2,4,6-Tri-substituted-1,3,5-Triazines
Molecules 2006, 11, 81-102 (PDF format 158 K)

(open access to this paper was granted by MDPI)
Hanne Hovelstad ¹, Ingebjorg Leirset ¹, Karin Oyaas ^1,† and Anne Fiksdahl ^2,*
1 Paper and Fibre Institute (PFI), Høgskoleringen 6B, NO-7491 Trondheim, Norway.
2 Department of Chemistry, Norwegian University of Science and Technology, NTNU, NO-7491 Trondheim, Norway.
† Current address: Gaia Lab AS, NO-7228 Kvaal, Norway.
* Author to whom correspondence should be addressed
Screening Analyses of Pinosylvin Stilbenes, Resin Acids and Lignans in Norwegian Conifers
Molecules 2006, 11, 103-114 (PDF format 174 K)

(open access to this paper was granted by MDPI after delay)  Edyta Błaż and Jan Pielichowski *
Department of Polymer Science and Technology, Krakow University of Technology, ul. Warszawska 24, 31-155 Krakow, Poland. Fax: +48 12 6282038
* Author to whom correspondence should be addressed
Polymer – Supported Cobalt (II) Catalysts for the Oxidation of Alkenes
Molecules 2006, 11, 115-120 (PDF format 194 K)


Wei-Min Chen
Department of Medicinal Chemistry, School of Pharmacy, Jinan University, Guangzhou, 510632, P.R. China; E-mail: twmchen@jnu.edu.cn
Synthetic Studies on Erythromycin Derivatives: Reactivity of the C12-21 Alkene
Molecules 2006, 11, 121-129 (PDF format 160 K)

Freddy Tjosaas † and Anne Fiksdahl *
Department of Chemistry, Norwegian University of Science and Technology, NTNU N-7491
Trondheim, Norway. † E-mail: tjosas@chem.ntnu.no
* To whom correspondence should be addressed; E-mail: Anne.Fiksdahl@chem.ntnu.no
A Simple Synthetic Route to Methyl 3-Fluoropyridine-4-carboxylate by Nucleophilic Aromatic Substitution
Molecules 2006, 11, 130-133 (PDF format 45 K)


Milan Cacic ^1,*, Mladen Trkovnik ², Frane Cacic ¹ and Elizabeta Has-Schon ³
1 Department of Chemistry, Faculty of Food Technology, University J.J.Strossmayer, Franje Kuhaca 18, 31 000 Osijek, Croatia
E-mail: mcacic@ptfos.hr E-mail: fcacic@ptfos.hr
2 F.Malnara 8, odvojak 7.  10 000 Zagreb, Croatia
3 Department of Biology, J.J.Strossmayer University, Gajev Trg 6,  31 000 Osijek, Croatia
E-mail: elschon@yahoo.com
* Author to whom correspondence should be addressed; E-mail: mcacic@ptfos.hr
Synthesis and Antimicrobial Activity of Some Derivatives on the Basis (7-hydroxy-2-oxo-2H-chromen-4-yl)-acetic Acid Hydrazide
Molecules 2006, 11, 134-147 (PDF format 113 K)


Damião Pergentino de Sousa*, Renata Rabelo Schefer, Ursula Brocksom and Timothy John Brocksom*
Laboratório de Química Bio-Orgânica, Departamento de Química, Universidade Federal de São Carlos,
Caixa Postal 676, 13565-905 São Carlos, SP, Brazil
*Authors to whom correspondence should be addressed. E-mail: brocksom@terra.com.br or damiao50@yahoo.com.br
Synthesis and Antidepressant Evaluation of Three para-Benzoquinone Mono-oximes and Their Oxy Derivatives
Molecules 2006, 11, 148-155 (PDF format 46 K)


Kanlaya Jumpatong 1, Weerachai Phutdhawong ^2,* and Duang Buddhasukh ^1,*
1 Department of Chemistry, Faculty of Science, Chiangmai University, Chiangmai, 50200, Thailand
2 Department of Chemistry, Faculty of Science, Maejo University, Chiangmai, 50292, Thailand
* Authors to whom correspondence should be addressed; e-mails: duang@chiangmai.ac.th;
weerachai@mju.ac.th, phutdhawong@gmail.com
Communication: Dechlorophyllation by Electrocoagulation
Molecules 2006, 11, 156-162 (PDF format 156 K)


Yonglian Zhang and Hong-Chang Liang*
Department of Chemistry and Biochemistry, San Diego State University, 5500 Campanile Drive, San
Diego, CA, 92182, USA; Fax: +1 (619) 594-4634; Tel: +1 (619) 594-6215. Home page URL:
http://www.chemistry.sdsu.edu/faculty/Liang/
*Author to whom correspondence should be addressed; e-mail: hcliang@sciences.sdsu.edu
Synthesis and Structural Characterization of the Sodium Salt of a New Sulfonate-containing Water Soluble N-Donor Ligand⎯ Self-assembly in the Solid State by π−π Stacking Interactions
Molecules 2006, 11, 163-168 (PDF format 143 K)


Long-Chih Hwang ^1,*, Chun-Hsien Tu ², Jung-Hui Wang ³ and Gene-Hsiang Lee ⁴
1 Faculty of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung City 80708, Taiwan, ROC
2 Department of Psychiatry, Longcyuan Veterans Hospital, Pingtung 912, Taiwan, ROC
3 Department of Pharmacy, Kaohsiung Veterans General Hospital, Kaohsiung City 807, Taiwan, ROC
4 Instrumentation Center, College of Science, National Taiwan University, Taipei City 106, Taiwan, ROC
* Author to whom correspondence should be addressed; e-mail: lnchhw@kmu.edu.tw
Synthesis and Molecular Structure of 6-Amino-3-benzylmercapto-1,2,4-triazolo[3,4-f][1,2,4]triazin-8(7H)-one
Molecules 2006, 11, 169-176 (PDF format 253 K)


M. Teresa Barros* and Ana Maria Faísca Phillips †
Departamento de Química e Centro de Química Fina e Biotecnologia, Faculdade de Ciências e
Tecnologia, Universidade Nova de Lisboa, Monte de Caparica, 2829-516 Caparica, Portugal. Tel.:
(+ 351) 212948300; Fax: (+ 351) 212948550; † E-mail: amfp@dq.fct.unl.pt
* Author to whom correspondence should be addressed; e-mail: mtbarros@dq.fct.unl.pt
Synthesis of New Chiral Amines with a Cyclic 1,2-Diacetal Skeleton Derived from (2R, 3R)-(+)-Tartaric Acid
Molecules 2006, 11, 177-196 (PDF format 155 K)


Peter Kotrusz ¹ and Stefan Toma ^2,*
1 SYNKOLA, s.r.o., SK-842 15 Bratislava, Slovakia.
2 Faculty of Natural Sciences, Comenius University Bratislava, SK-84215 Bratislava, Slovakia.
* Author to whom correspondence should be addressed; e-mail: toma@fns.uniba.sk
L-Proline Catalyzed Michael Additions of Thiophenols to α,β-Unsaturated Compounds, Particularly α-Enones, in the Ionic Liquid [bmim]PF6
Molecules 2006, 11, 197-205 (PDF format 100 K)


Hamid Latif Siddiqui ^1,* Amjid Iqbal ¹, Saeed Ahmad ³ and George W. Weaver ^2,*
1 Institute of Chemistry, University of the Punjab, Lahore-5400, Pakistan
2 Department of Chemistry, Loughborough University, Loughborough, LE11 3TU, UK
3 Pakistan Council of Science and Industrial Research Complex, Lahore, Pakistan
* Authors to whom correspondence should be addressed: E-mail: drhamidlatif@yahoo.com; G.W.Weaver@lboro.ac.uk
Short Communication: Synthesis and Spectroscopic Studies of New Schiff Bases
Molecules 2006, 11, 206-211 (PDF format 67 K)

David Díaz Díaz ^†, Antonella Converso, K. Barry Sharpless and M. G. Finn *
Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research
Institute, 10550 N. Torrey Pines Rd., La Jolla, California 92037, USA; e-mails:
converso@scripps.edu, sharples@scripps.edu
† Present address: Departamento de Química Orgánica, Universidad Autónoma de Madrid, 28049
Madrid, Spain; e-mail: david.diaz@uam.es
* Author to whom correspondence should be addressed; E-mail: mgfinn@scripps.edu
2,6-Dichloro-9-thiabicyclo[3.3.1]nonane: Multigram Display of Azide and Cyanide Components on a Versatile Scaffold
Molecules 2006, 11, 212-218 (PDF format 216 K)


Sergei V. Trepalin ^1,*, Alexander V. Yarkov ¹, Igor V. Pletnev ² and Andrei A. Gakh ^3,*
1  Institute of Physiologically Active Compounds RAS, 142432 Chernogolovka, Moscow Region, Russia, Tel. +7 (095) 135-6369.
2 Chemistry Department, Moscow State University, 117234, Moscow, Russia.
3  Oak Ridge National Laboratory, Oak Ridge, Tennessee, 37831-6242, USA, Tel. +1 (865) 574-1000.
* Authors to whom correspondence should be addressed; e-mails: trep@chemical-block.com and gakhaa@ornl.gov
A Java Chemical Structure Editor Supporting the Modular Chemical Descriptor Language (MCDL)
Molecules 2006, 11, 219-231 (PDF format 85 K)
Publisher's Note added on 29 June 2006:
There is a pagination error in this paper. The page number for the first page (Sergei V. Trepalin et al. Molecules 2006, 11, 219) is assigned correctly. However, the following pages were not correctly paginated and the final page number should be 231 instead of 241. The original file is still provided.
Pages 232-241 are thus taken as blank pages. We apologize for this error and for any inconvenience.


Martin Dolezal ^1,*, Lukas Palek ¹, Jarmila Vinsova ¹, Vladimir Buchta ¹, Josef Jampilek ² and Katarina Kralova ³
1 Faculty of Pharmacy in Hradec Kralove, Charles University in Prague, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic.
2 Zentiva, a.s. U Kabelovny 130, 102 37 Prague 10, Czech Republic.
3 Institute of Chemistry, Faculty of Natural Sciences, Comenius University, Mlynska Dolina, 842 15 Bratislava, Slovak Republic.
† Preliminary results were presented at the Seventh Electronic Conference on Synthetic Organic Chemistry (ECSOC-7, http://www.mdpi.net/ecsoc-7), November 1-30, 2003 (paper C001).
* Author to whom correspondence should be addressed; e-mail: martin.dolezal@faf.cuni.cz; Tel.: (+420) 49-5067272; Fax: (+420) 49-5512423.
Substituted Pyrazinecarboxamides: Synthesis and Biological Evaluation †
Molecules 2006, 11, 242-256 (PDF format 104 K)


Turgut Kilic
Balikesir University, Faculty of Arts and Sciences, Department of Chemistry, 10100, Balikesir, Turkey
Tel: (+90) 266 – 249 33 58; Fax: (+90) 266 – 249 33 60; E-mail: tkilic@balikesir.edu.tr
Short Communication: Isolation and Biological Activity of New and Known Diterpenoids From Sideritis stricta Boiss. & Heldr.
Molecules 2006, 11, 257-262 (PDF format 56 K)


Hong-Bin Sun ^1,2, Ruimao Hua ^1,* and Yingwu Yin ²
1 Key Laboratory of Organic Optoelectronics & Molecular Engineering of Ministry of Education, Beijing 100084, China
2 Key Laboratory of Bioorganic Phosphorus Chemistry of Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, China
* Author to whom correspondence should be addressed; Tel./Fax +86-10-62792596, e-mail: ruimao@mail.tsinghua.edu.cn
ZrOCl₂·8H₂O: An Efficient, Cheap and Reusable Catalyst for the Esterification of Acrylic Acid and Other Carboxylic Acids with Equimolar Amounts of Alcohols
Molecules 2006, 11, 263-271 (PDF format 52 K)


Gang Liu, Song Yang, Baoan Song *, Wei Xue, Deyu Hu, Linhong Jin and Ping Lu
Center for Research and Development of Fine Chemicals, Guizhou University, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guiyang, 550025, P. R. China
E-mails: fcc.gliu@gzu.edu.cn, yangsdqj@126.com, shouldww@163.com, fcc.dyhu@gzu.edu.cn, fcc.lhjin@gzu.edu.cn, luping217@sohu.com
* Author to whom correspondence should be addressed; e-mail:songbaoan22@yahoo.com, Tel.:(+86)851 3620521, Fax: (+86)851 3622211
Microwave Assisted Synthesis of N-Arylheterocyclic Substituted-4-aminoquinazoline Derivatives
Molecules 2006, 11, 272-278 (PDF format 47 K)


Emil Popovski ^1,*, Jane Bogdanov ¹, Metodija Najdoski ¹ and Evamarie Hey-Hawkins ²
1 Institute of Chemistry, Faculty of Natural Sciences & Mathematics, Sts. Cyril and Methodius University, PO Box 162, 1000 Skopje, Macedonia; E-mails: jbb15@psu.edu,
metonajd@iunona.pmf.ukim.edu.mk
2 Faculty of Chemistry and Mineralogy, University of Leipzig, Johannsallee 29, D-04103 Leipzig, Germany; E-mail: hey@rz.uni-leipzig.de
* Author to whom correspondence should be addressed; E-Mail: emilp@iunona.pmf.ukim.edu.mk
Reactions of (Benzamidomethyl)triethylammonium Chloride with Some Inorganic Nucleophiles in Aqueous Media
Molecules 2006, 11, 279-285 (PDF format 58 K)


Petr Knesl, Dirk Röseling and Ulrich Jordis *
Institute of Applied Synthetic Chemistry, Vienna University of Technology, Getreidemarkt 9, 1060 Vienna, Austria
* Author to whom correspondence should be addressed; E-mail: ujordis@pop.tuwien.ac.at
Improved Synthesis of Substituted 6,7-Dihydroxy-4-quinazolineamines: Tandutinib, Erlotinib and Gefitinib
Molecules 2006, 11, 286-297 (PDF format 67 K)


Sofia M. Bruno, Bernardo Monteiro, Maria Salete Balula, Catarina Lourenço, Anabela A.Valente, Martyn Pillinger, Paulo Ribeiro-Claro and Isabel S. Gonçalves *
Department of Chemistry, CICECO, University of Aveiro, 3810-193 Aveiro, Portugal
* Author to whom correspondence should be addressed; E-mail: igoncalves@dq.ua.pt
Catalytic Properties of the Dioxomolybdenum Siloxide MoO₂(OSiPh₃)₂ and its 2,2'-Bipyridine Adduct MoO₂(OSiPh₃)₂(bpy)
Molecules 2006, 11, 298-308 (PDF format 115 K)

Neeranuch Chairungsi ¹ Kanlaya Jumpatong ¹ Weerachai Phutdhawong ^2,* and Duang Buddhasukh ^1,*
1 Department of Chemistry, Faculty of Science, Chiangmai University, Chiang Mai, 50200, Thailand
2 Department of Chemistry, Faculty of Science, Maejo University, Chiang Mai, 50292, Thailand
* Authors to whom correspondence should be addressed; emails: weerachai@mju.ac.th; duang@chiangmai.ac.th
Full Paper: Solvent Effects in Electrocoagulation of Selected Plant Pigments and Tannin
Molecules 2006, 11, 309-317 (PDF format 142 K)


Ricardo A.W. Neves Filho and Rajendra M. Srivastava *
Departamento de Química Fundamental, Universidade Federal de Pernambuco, 50.740-540 Recife, PE, Brazil
*Author to whom correspondence should be addressed, e-mail: rms_indu@yahoo.com
Full Paper: A Handy and Solventless Direct Route to Primary 3-[3-Aryl)-1,2,4-oxadiazol-5-yl]propionamides Using Microwave Irradiation
Molecules 2006, 11, 318-324 (PDF format 48 K)


Livio Racane ¹, Ranko Stojkovic ², Vesna Tralic-Kulenovic ¹ and Grace Karminski-Zamola ^3,*
1 Department of Applied Chemistry, Faculty of Textile Technology, University of Zagreb, Prilaz
baruna Filipovića 30, 10000 Zagreb, Croatia; e-mails: lracane@ttf.hr; vtralic@ttf.hr
2 Division of Molecular Medicine, Ruder Boskovic Institute, Bijenicka cesta 54, 10000 Zagreb,
Croatia; e-mail: stojkov@irb.hr
3 Department of Organic Chemistry, Faculty of Chem. Eng. and Technology, University of Zagreb, Marulićev trg 19, 10000 Zagreb, Croatia
* Author to whom correspondence should be addressed; e-mail: gzamola@fkit.hr
Full Paper: Synthesis and Antitumor Evaluation of Novel Derivatives of 6-Amino-2-phenylbenzothiazoles
Molecules 2006, 11, 325-333 (PDF format 68 K)

(open access to this paper was granted by MDPI after delay) 
Oscar Cruciani ¹, Luisa Mannina ^1,2,*, Anatoli P. Sobolev ¹, Cesare Cametti ³ and AnnaLaura Segre ¹
1 Istituto di Metodologie Chimiche, CNR, 00016 Monterotondo Stazione, Roma, Italy
Tel. (+39)06 90672385; Fax (+39)06 90672477.
2 Dipartimento S.T.A.A.M, Università degli Studi del Molise, 86100 Campobasso, Italy
3 Dipartimento di Fisica, Università di Roma "La Sapienza", piazz. A. Moro, 2, 00185 Roma, Italy and Istituto Nazionale per la Fisica della Materia (INFM), Unità di Roma1, Roma, Italy
* Author to whom correspondence should be addressed
Full Paper: An Improved NMR Study of Liposomes Using 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospatidylcholine as Model
Molecules 2006, 11, 334-344 (PDF format 130 K)

(open access to this paper was granted by MDPI after delay) 
Elena Pérez-Mayoral ¹, Elena Soriano ², Sebastián Cerdán ² and Paloma Ballesteros ^1,*
1 Laboratorio de Síntesis Orgánica e Imagen Molecular por Resonancia Magnética, Instituto Universitario de Investigación, UNED, Facultad de Ciencias, UNED, Paseo Senda del Rey 9, E-28040 Madrid, Spain; E-mail for Elena Pérez: eperez@bec.uned.es
2 Laboratorio de Resonancia Magnética, Instituto de Investigaciones Biomédicas, CSIC, Arturo Duperier 4, E-28029 Madrid, Spain
† Preliminary results were presented at the 9th International Electronic Conference on Synthetic
Organic Chemistry (ECSOC 9, http://www.mdpi.org/ecsoc-9), November 1-30, 2005 (paper C003)
* Author to whom correspondence should be addressed. Phone: (+34) 913987320. Fax: (+34)
913986697
Full Paper: Experimental and Theoretical Study of Lanthanide Complexes Based on Linear and Macrocyclic Polyaminopolycarboxylic Acids Containing Pyrazolylethyl Arms†
Molecules 2006, 11, 345-356 (PDF format 101 K)

(open access to this paper was granted by MDPI after delay) 
Marko D. Mihovilovic,* Thomas C. M. Fischer and Peter Stanetty
Vienna University of Technology – Institute of Applied Synthetic Chemistry, Getreidemarkt 9/163-OC, A-1060 Vienna, Austria
* Author to whom correspondence should be addressed
Full Paper: Synthesis of Novel Sterically Demanding Carbo- and Heterocyclic β-Ketoesters
Molecules 2006, 11, 357-364 (PDF format 76 K)

1 Dipartimento di Chimica Organica e Industriale, Università degli Studi di Milano, via Venezian 21, 20133 Milano, Italy
2 Dipartimento di Scienze dell’Ambiente e del Territorio, Università di Milano-Bicocca, p.za della Scienza 1, 20126 Milano, Italy
* Author to whom correspondence should be addressed
Communication: Selective Enzymatic Reduction of Aldehydes
Molecules 2006, 11, 365-369 (PDF format 38 K)


Correction: Molecules 2002, 7, 885-895
Molecules 2006, 11, 370 (PDF format 13 K)


Gernot A. Eller * and Wolfgang Holzer †
Department of Drug Synthesis, Faculty of Life Sciences, University of Vienna, Austria; † E-Mail:
wolfgang.holzer@univie.ac.at
* Author to whom correspondence should be addressed. E-mail: gernot.eller@univie.ac.at
Short Paper: First Synthesis of 3-Acetyl-2-aminothiophenes Using the Gewald Reaction
Molecules 2006, 11, 371-376 (PDF format 58 K)


Hooshang Hamidian, Ahmad Momeni Tikdari * and Hojatollah Khabazzadeh
Department of Chemistry, Shahid Bahonar University of Kerman, Kerman 76175-133, Iran
* Author to whom correspondence should be addressed; E-mail: amomeni@mail.uk.ac.ir
Full Paper: Synthesis of New 4(3H)-Quinazolinone Derivatives Using 5(4H)-Oxazolones
Molecules 2006, 11, 377-382 (PDF format 47 K)

Guiping Ouyang, Peiquan Zhang, Gangfang Xu, Baoan Song *, Song Yang, Linhong Jin, Wei Xue, Deyu Hu, Ping Lu and Zhuo Chen
Center for Research and Development of Fine Chemicals, Guizhou University, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guiyang, 550025, P. R. China. E-mails: oygp710@163.com, pqzhang@126.com, xuguangf04@163.com, yangsdqj@126.com, fcc.lhjin@gzu.edu.cn, shouldww@163.com, fcc.dyhu@gzu.edu.cn, luping217@sohu.com
*Author to whom correspondence should be addressed; E-mail:songbaoan22@yahoo.com Tel.:(+86) 851 3620521, Fax: (+86) 851 3622211
Full Paper: Synthesis and Antifungal Bioactivities of 3-Alkylquinazolin- 4-one Derivatives
Molecules 2006, 11, 383-392 (PDF format 71 K)


Hongxia He ¹, Mengjia Liu ¹, Zhibing Zheng ^2,*, Ying Liu ², Junhai Xiao ², Ruibin Su ², Chun Hu ¹, Jin Li ², and Song Li ²
1 School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, 110016, P.R. China
2 Department of Medicinal Chemistry, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, P.R. China
E-mail addresses: Zhibing ZHENG: zbzheng@nic.bmi.ac.cn, Mengjia Liu: mj32800@yahoo.com.cn, Ying Liu: luxin314@sina.com, Junhai Xiao: xiaojunhai@yahoo.com.cn, Ruibin Su:
Ruibinsu@Yahoo.com, Chun HU: Chem2000@163.com, Jin Li: lijin@nic.bmi.ac.cn, Song LI: lis@nic.bmi.ac.cn
*Author to whom correspondence should be addressed; e-mail: hhx110015@yahoo.com.cn
Full Paper: Synthesis and Analgesic Activity Evaluation of Some Agmatine Derivatives
Molecules 2006, 11, 393-402 (PDF format 127 K)


Meglena I. Kandinska ¹, Ivan D. Kozekov ² and Mariana D. Palamareva ^1,*
1 Department of Chemistry, University of Sofia, 1 James Bouchier Avenue, Sofia 1164, Bulgaria
2 Vanderbilt University, Chemistry Department, P. O. Box 1822-B, Nashville, TN 37235, USA
* Author to whom correspondence should be addressed; e-mail mpalamareva@chem.uni-sofia.bg
Received: 10 May 2006 / Accepted: 8 June 2006 / Published: 12 June 2006
Full Paper: Synthesis of New trans-2-Benzyl-3-(furan-2-yl)-4-substituted-1,2,3,4-tetrahydroisoquinolinones
Molecules 2006, 11, 403-414 (PDF format 87 K)


Carlos Pérez Medina*, Concepción López * and Rosa M. Claramunt †
Departamento de Química Orgánica y Bio-Orgánica, Facultad de Ciencias, UNED Senda del Rey 9, E-28040 Madrid (Spain); † e-mail: rclaramunt@ccia.uned.es
* Authors to whom correspondence may be addressed; e-mails: cperez@bec.uned.es, clopez@ccia.uned.es
Communication: Theoretical Studies on the Tautomerism of 1,5,6,7-Tetrahydro-4H-indazol-4-ones
Molecules 2006, 11, 415-420 (PDF format 59 K)


Luiz F. Silva, Jr*
Instituto de Química, Universidade de São Paulo, CP 26077, CEP 05513-970, São Paulo SP, Brazil;
Tel. (+55)-11-3091-2388, Fax (+55)-11-3815-5579
* Author to whom correspondence should be addressed; e-mail: luizfsjr@iq.usp.br
Review: Hypervalent Iodine–Mediated Ring Contraction Reactions
Molecules 2006, 11, 421-434 (PDF format 105 K)


Narciso M. Garrido*, David Díez, Sara H. Domínguez, M. Rosa Sánchez, Mercedes García and Julio G. Urones
Departamento de Química Orgánica, Universidad de Salamanca, Plaza de los Caídos 1-5, 37008, Salamanca, Spain; Tel. (+34) 923-294474, Fax (+34) 923-294574
* Author to whom correspondence should be addressed; e-mail: nmg@usal.es
Full Paper: A Convenient Asymmetric Synthesis of a β-amino Ester with Additional Functionalization as a Precursor for Peptide Nucleic Acid (PNA) Monomers
Molecules 2006, 11, 435-443 (PDF format 93 K)


Long-Chih Hwang ^1,*, Shin-Yi Jane ¹, Hsing-Yi Lai ¹, Chun-Hsien Tu ^2,† and Gene-Hsiang Lee ^3,†
1 Faculty of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung City 80708, Taiwan, ROC
2 Department of Psychiatry, Longcyuan Veterans Hospital, Pingtung 912, Taiwan, ROC
3 Instrumentation Center, College of Science, National Taiwan University, Taipei City 106, Taiwan, ROC
† E-mails: aromatu@mail.vhlc.gov.tw; ghlee@ntu.edu.tw
Full Paper: Synthesis, Molecular Structure and Characterization of Allylic Derivatives of 6-Amino-3-methyl-1,2,4-triazolo[3,4-f][1,2,4]-triazin-8(7H)-one
Molecules 2006, 11, 444-452 (PDF format 260 K)


Almudena Perona ^1,*, Dionisia Sanz ^1,*, Rosa M. Claramunt  ^1,† and José Elguero ²
1 Departamento de Química Orgánica y Bio-Orgánica, Facultad de Ciencias, UNED, Senda del Rey 9, E-28040 Madrid, Spain; †e-mail: rclaramunt@ccia.uned.es
2 Instituto de Química Médica (CSIC), Centro de Química Orgánica 'Manuel Lora Tamayo', Juan de la Cierva 3, E-28006 Madrid, Spain; e-mail: iqmbe17@iqm.csic.es
* Authors to whom correspondence should be addressed; Fax: (+34) 913988372; e-mail: aperona@bec.uned.es; dsanz@ccia.uned.es
Full Paper: Syntheses and Structural Studies of Schiff Bases Involving Hydrogen Bonds
Molecules 2006, 11, 453-463 (PDF format 211 K)


Zhang-Gao Le ^1,*, Zong-Bo Xie ¹ and Min Ying ²
1 Department of Applied Chemistry, East China Institute of Technology, Fuzhou, 344000, Jiangxi, P. R. China; E-mail:; Telephone: (+86)-794-8250216; Fax: (+86)-794-8258310
2 Zhejiang Wanli University, Ningbo, 315100, Zhejiang, P. R. China; E-mail: Yingm@zwu.edu.cn
* Author to whom correspondence should be addressed; e-mail: Lezhang_ecit@163.com
Full Paper:  Ionic Liquid-promoted Ring-closure Reactions between 1,4-Dihydroxyanthraquinone and Diamines
Molecules 2006, 11, 464-468 (PDF format 58 K)


Olcay Bekircan* and Hakan Bektas
Department of Chemistry, Giresun Faculty of Arts and Sciences, Karadeniz Technical University, 28049, Giresun, Turkey; Fax (+90) 454 2164518
*Author to whom correspondence should be addressed; e-mail: obekircan@ktu.edu.tr
Full Paper: Synthesis of New Bis-1,2,4-Triazole Derivatives
Molecules 2006, 11, 469-477 (PDF format 77 K)


Fernando Herranz *, Mª Dolores Santa María * and Rosa M. Claramunt †
Departamento de Química Orgánica y Bio-Orgánica, Universidad Nacional de Educación a Distancia
(UNED), Facultad de Ciencias, Senda del Rey 9, E-28040 Madrid, Spain; Tel.: + 34 91 3987322; fax:
+ 34 91 3988372; † e-mail: rclaramunt@ccia.uned.es
* Authors to whom correspondence may be addressed; e-mail: fherranz@cbm.uam.es; dsanta@ccia.uned.es
Full Paper: Host-Guest Chemistry of Tolbutamide
Molecules 2006, 11, 478-485 (PDF format 225 K)

(open access to this paper was granted by MDPI after delay) 
Andrew J. Walsh, Michael L. Davis and William Fraser *
School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham, B4 7ET, UK
Tel.: +44 121 204 3940, Fax. +44 121 359 0733
* Author to whom correspondence should be addressed
Full Paper: Solid Phase Synthesis of a Metronidazole Oligonucleotide Conjugate
Molecules 2006, 11, 486-495 (PDF format 76 K)

Shu-Kun Lin
Molecular Diversity Preservation International (MDPI), Matthaeusstrasse 11, Basel CH-4057
Switzerland. Tel. ++41 79 322 3379, Fax: ++41 61 302 8918, E-mail: lin@mdpi.org, http://www.mdpi.org/lin
Editorial: Delayed Open Access or Permanent Non-Open Access
Molecules 2006, 11, 496-497 (PDF format 15 K, HTML format)


Fatma E. M. El-Baih ^1,*, Hanan A. S. Al-Blowy ¹ and Hassan M. Al-Hazimi ²
1 Women Students-Medical Studies & Sciences Sections, Chemistry Department, College of Science,
King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia. Tel.: (+966-1) 477-2245, Fax:
(+966-1) 477-2245.
2 Chemistry Department, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451,
Saudi Arabia. Tel.: (+966-1) 467-5905, Fax: (+966-1) 467-5992. E-mail: hhazimi@ksu.edu.sa
* Author to whom correspondence should be addressed; E-mail: zahraa205@yahoo.com
Full Paper: Synthesis of Some Thienopyrimidine Derivatives
Molecules 2006, 11, 498-513 (PDF format 119 K)


Neeranuch Chairungsi ¹, Kanlaya Jumpatong ¹, Patiwat Suebsakwong ², Waya Sengpracha ³,
Weerachai Phutdhawong ^2,* and Duang Buddhasukh ^1,*
1 Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand
2 Department of Chemistry, Faculty of Science, Maejo University, Chiang Mai, 50292, Thailand
3 Department of Chemistry, Faculty of Science, Silpakorn University, Nakhon Pathom, 73000, Thailand
* Authors to whom correspondence should be addressed; emails: weerachai@mju.ac.th; duang@chiangmai.ac.th
Full Paper: Electrocoagulation of Quinone Pigments
Molecules 2006, 11, 514-522 (PDF format 74 K)


Om Prakash *, Kamaljeet Pannu, Richa Prakash and Anita Batra
Department of Chemistry, Kurukshetra University, Kurukshetra, Haryana, India
* Author to whom correspondence should be addressed; Fax: (+91) 1744 238277; e-mail: dromprakash50@rediffmail.com
Short Communication: [Hydroxy(tosyloxy)iodo]benzene Mediated α-Azidation of Ketones
Molecules 2006, 11, 523-527 (PDF format 63 K)


Ana C. Coelho ¹, Filipe A. Almeida Paz ¹, Jacek Klinowski ², Martyn Pillinger ¹ and Isabel S. Gonçalves ^1,*
1 Department of Chemistry, CICECO, University of Aveiro, 3810-193 Aveiro, Portugal
2 Department of Chemistry, University of Cambridge, Lensfield Road, CB2 1EW, Cambridge, United Kingdom; E-mail: jk18@cam.ac.uk
* Author to whom correspondence should be addressed; E-mail: igoncalves@dq.ua.pt
Full Paper: Synthesis and Structure of a Sodium Complex of an Aromatic β-Diketone and Pyrazolylpyridine
Molecules 2006, 11, 528-538 (PDF format 385 K)


Kunimitsu Kaya ^1,*, Louise F. Morrison ², Geoffrey A. Codd ^2,*, James S. Metcalf ², Tomoharu Sano ³, Hiroo Takagi ³ and Takuya Kubo ¹
1 Graduate School of Environmental Studies, Tohoku University, Aoba-ku, Sendai 980-8579, Japan,
E-mail: kubo@mail.kankyo.tohoku.ac.jp
2 Division of Environmental and Applied Biology, School of Life Sciences, University of Dundee,
Dundee DD1 4HN, UK. E-mails: L.F.morrison@dundee.ac.uk; j.s.metcalf@dundee.ac.uk
3 National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba Ibaraki 305-8506, Japan,
E-mails: sanotomo@nies.go.jp; takakiho@nies.go.jp
*Authors to whom correspondence should be addressed; E-mail: kaya@mail.kankyo.tohoku.ac.jp,
Tel: (+81)-22-795-4506; Fax: (+81)-22-795-4506; E-mail: g.a.codd@dundee.ac.uk
Full Paper: A Novel Biosurfactant, 2-Acyloxyethylphosphonate, Isolated from Waterblooms of Aphanizomenon flos-aquae
Molecules 2006, 11, 539-548 (PDF format 119 K)


Peng Wang ^1,2, Chui Hua Kong ^1,* and Chao Xian Zhang ³
1 Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, P.R. China
2 Graduate School, Chinese Academy of Sciences, Beijing 100039, P.R. China
3 Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100094, P.R. China
E-mails: wangpeng@iae.ac.cn (Peng Wang); cxzhang@wssc.org.cn (Chao Xian Zhang)
* Author to whom correspondence should be addressed; e-mail: kongch@iae.ac.cn; Fax: (+86)-24-83970300
Full Paper: Chemical Composition and Antimicrobial Activity of the Essential Oil from Ambrosia trifida L.
Molecules 2006, 11, 549-555 (PDF format 63 K)


Mehdi Ghandi *, Farshid Salimi and Abolfazl Olyaei
School of Chemistry, University College of Science, University of Tehran, Tehran, Iran
* Author to whom correspondence should be addressed. E-mail: ghandi@khayam.ut.ac.ir; Tel.: (+98)-21-61112250; Fax: (+98)-21-66495291
Full Paper: Novel Reaction of N,N'-Bisarylmethanediamines with Formaldehyde. Synthesis of Some New 1,3,5-Triaryl-1,3,5-hexahydrotriazines
Molecules 2006, 11, 556-563 (PDF format 57 K)


Miroslava Martinková *, Jozef Gonda and Jana Raschmanová
Institute of Chemical Sciences, Department of Organic Chemistry, P. J. Šafárik University, Moyzesova
11, SK-040 01 Košice, Slovak Republic. Tel.: (+ 421) 556228332; Fax: (+ 421) 556222421
E-mails: Jozef Gonda: jgonda@kosice.upjs.sk, Jana Raschmanova: jrasch@pobox.sk
* Author to whom correspondence should be addressed; e-mail: mmartin@kosice.upjs.sk
Full Paper: Novel Furanoid α-Substitued α-Amino Acid as a Potent Turn Mimic in Peptide Synthesis
Molecules 2006, 11, 564-573 (PDF format 113 K)


Juan Li †, Yan-Fang Zhao ‡, Xiao-Ye Yuan, Jing-Xiong Xu and Ping Gong *
School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, 103 Wenhua Road,
Shenhe District, 110016 Shenyang, Liaoning, P. R. China; Fax: (+86) 24-23882925/23986426, Phone:
(+86) 24-23986426; E-mails: † lijuan107628@sian.com; ‡ yanfangzhao@126.com
* Author to whom correspondence should be addressed; E-mail: gongpinggp@126.com or gongping@syphu.edu.cn
Full Paper: Synthesis and Anticancer Activities of Novel 1,4-Disubstituted Phthalazines
Molecules 2006, 11, 574-582 (PDF format 75 K)

Santos Fustero ^1,* Javier González ² and Carlos del Pozo ^1,*
1 Departamento de Química Orgánica, Universidad de Valencia, 46100-Burjassot, Valencia (Spain).
2 Departamento de Química Orgánica e Inorgánica, Universidad de Oviedo, Julián Clavería 8, 33006 Oviedo (Spain).
* Authors to whom correspondence should be addressed. E-mails: santos.fustero@uv.es, carlos.pozo@uv.es
Communication: 1,4-Benzodiazepine N-Nitrosoamidines: Useful Intermediates in the Synthesis of Tricyclic Benzodiazepines
Molecules 2006, 11, 583-588 (PDF format 44 K)


Gene-Hsiang Lee † and Hsin-Ta Wang*
Institute of Organic and Polymeric Materials, National Taipei University of Technology, Taipei 106,
Taiwan, ROC; † e-mail: ghlee@ntu.edu.tw
* Author to whom correspondence should be addressed; e-mail: htwang@ntut.edu.tw
Full Paper: Synthesis and Molecular Structures of Two [1,4-bis(3-pyridyl)-2,3-diazo-1,3-butadiene]-dichloro-Zn(II) Coordination Polymers
Molecules 2006, 11, 589-596 (PDF format 266 K)


Souad Kasmi-Mir ^1,*, Ayada Djafri ³, Ludovic Paquin ^2,†, Jack Hamelin ² and Mustapha Rahmouni ^1,‡
1 Laboratoire Synthèse et Catalyse, LSCT, Université Ibn Khaldoun, Tiaret, Algeria; E-mail:‡rahmouni@mail.univ-tiaret.dz
2 ICMV, UMR 6226, Université de Rennes 1, Campus de Beaulieu, Bt10A 35042-Rennes, France;E-mail: †ludovic.paquin@univ-rennes1.fr
3 Laboratoire Synthèse Organique Appliquée, Université Essénia, Oran, Algeria; Fax : (+213) 41 4191 84.
* Author to whom correspondence should be addressed: E-mail: kasmi@mail.univ-tiaret.dz
Communication: One-Pot Synthesis of 5-Arylidene-2-Imino-4-Thiazolidinones under Microwave Irradiation
Molecules 2006, 11, 597-602 (PDF format 48 K)


Çigdem Yolacan ¹, Emine Bagdatli ¹, Nüket Öcal ^1,* and Dieter E. Kaufmann ^2,*
1 Yıldız Technical University, Faculty of Art and Sciences, Department of Chemistry, Davutpasa Campus, 34210, Istanbul, Turkey
2 Clausthal University of Technology, Institute of Organic Chemistry, Leibnizstr. 6, D-38678 Clausthal-Zellerfeld, Germany
* Authors to whom correspondence may be addressed; e-mails: nocal@yildiz.edu.tr; dieter.kaufmann@tu-clausthal.de
Full Paper: Epibatidine Alkaloid Chemistry: 5. Domino-Heck Reactions of Azabicyclic and Tricyclic Systems
Molecules 2006, 11, 603-614 (PDF format 77 K)


Jerzy Kossakowski *, Mariola Krawiecka and Bożena Kuran
Department of Medical Chemistry, Medical University, 3 Oczki St., 02-007 Warsaw, Poland
* Author to whom correspondence should be addressed: email: jerzykos@amwaw.edu.pl; Tel.: (+48) 22 628 06 79
Full Paper: Synthesis of Conformationally Constrained Aryl- or Heteroarylpiperazinyl Derivatives of Selected Imides as 5-HT1A Receptor
Ligands
Molecules 2006, 11, 615-626 (PDF format 90 K)


Akihiro Yoshida ^{1, †}, Xiuhua Hao ¹, Osamu Yamazaki ¹ and Joji Nishikido ^1,*
1 The Noguchi Institute, Itabashi-ku, Tokyo 173-0003, Japan; † e-mail: ayoshida@noguchi.or.jp
2 Asahi Kasei Corporation, Fuji, Shizuoka 416-8501, Japan
* Author to whom correspondence should be addressed; e-mail: nishikido.jc@om.asahi-kasei.co.jp
Review: Development of Fluorous Lewis Acid-Catalyzed Reactions
Molecules 2006, 11, 627-640 (PDF format 326 K)


Luo-Ting Yu ^1,2,5, Ji-Ling Huang ¹, Ching-Yao Chang ^3,4 and Teng-Kuei Yang ^3,5,*
1 Laboratory of Organometallic Chemistry, East China University of Science & Technology, Shanghai, 200237, P.R. China
2 Department of Pharmaceutical and Biochemical Engineering, Sichuan University, Sichuan, 610065, P.R. China
3 Department of Chemistry, National Chung-Hsing University, Taichung, 402, Taiwan
4 Department of Biotechnology and Bioinformatics, Asia University, Wufeng, Taichung, 413, Taiwan
5 Wisdom Pharmaceutical Co. Ltd., Haimen, Jiangsu, 226100, P.R. China
*Author to whom correspondence should be addressed; e-mail: tk@wisdompharma.com
Full Paper: Formal Synthesis of the ACE Inhibitor Benazepril·HCl via an Asymmetric Aza-Michael Reaction
Molecules 2006, 11, 641-648 (PDF format 100 K)

Mehdi Adib,* Khadijeh Ghanbary, Manizheh Mostofi and Mohammad Reza Ganjali
School of Chemistry, University College of Science, University of Tehran, P. O. Box 14155-6455, Tehran, Iran
* Author to whom correspondence should be addressed; Tel/fax: +98(21)66495291; E-mail:
madib@khayam.ut.ac.ir
Full Paper: Efficient Ce(NO₃)₃·6H2O-Catalyzed Solvent-Free Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones
Molecules 2006, 11, 649-654 (PDF format 57 K)


Jo N. D'herde and Pierre J. De Clercq *
Ghent University, Department of Organic Chemistry, Laboratory for Organic Synthesis, Krijgslaan
281 (S4), B-9000 Gent, Belgium
* Author to whom correspondence should be addressed: E-mail: pierre.declercq@UGent.be
Full Paper: Application of the Solid-Phase Julia–Lythgoe Olefination in Vitamin D Side-Chain Construction
Molecules 2006, 11, 655-660 (PDF format 64 K)

Quan-Lin Yu ^1,2, Hong-Quan Duan ³, Yoshihisa Takaishi ⁴ and Wen-Yuan Gao ^1,*
1 College of Pharmaceutical Sciences and Biotechnology, Tianjin University, Tianjin 300072, P.R. China; E-mail: quanlin_yu@yahoo.com.cn
2 School of Agronomy, Hebei Normal University of Science & Technology, Hebei Cangli, 066600, P.R. China
3 School of Pharmacy, Tianjin Medical University, Tianjin 300070, P.R. China; E-mail: duanhq@tijmu.edu.cn
4 Faculty of Pharmaceutical Sciences, University of Tokushima, 770-8505, Japan; E-mail: takaishi@ph.tokushima-u.ac.jp
* Author to whom correspondence should be addressed. E-mail: wy_gao1@yahoo.com.cn; Tel: (+86) 22 87401895; Fax: (+86) 22 87401895
Received: 28 July 2006; in revised form: 11 August 2006 / Accepted: 30 August 2006 / Published: 4 September 2006
Communication: A Novel Triterpene from Centella asiatica
Molecules 2006, 11, 661-665 (PDF format 61 K)

Yingshu Xu  ^1,2, Kai Yan ¹, Baoan Song ^1,*, Gangfang Xu ¹, Song Yang ¹, Wei Xue ¹, Deyu Hu ¹, Ping Lu ¹, Guiping Ouyang ¹, Linhong Jin ¹ and Zhuo Chen ¹
1 Center for Research and Development of Fine Chemicals, Guizhou University, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guiyang, 550025, P. R. China; E-mails: xuyingshu1976@126.com, xuguangf04@163.com, yangsdqj@126.com, shouldww@163.com, fcc.dyhu@gzu.edu.cn, luping217@sohu.com, oygp710@163.com, fcc.lhjin@gzu.edu.cn, gychenzhuo@yahoo.com.cn
2 Laboratory of Medicinal Chemistry, Zunyi, Medical College, 563003, Zunyi, P. R. China
* Author to whom correspondence should be addressed; E-mail: songbaoan22@yahoo.com Tel: (+86) 851 3620521, Fax: (+86) 851 3622211.
Received: 9 August 2006; in revised form: 5 September 2006 / Accepted: 5 September 2006 / Published: 6 September 2006
Full Paper: Synthesis and Antiviral Bioactivities of α-Aminophosphonates Containing Alkoxyethyl Moieties
Molecules 2006, 11, 666-676 (PDF format 181 K)

Tiejun Ling ^1,*, Tao Xia ¹, Xiaochun Wan ¹, Daxiang Li ¹ and Xiaoyi Wei ²
1 Key Laboratory of Tea Biochemistry and Biotechnology of Ministry of Education and Ministry of Agriculture, Anhui Agricultural University, Hefei 230036, P.R. China; E-mails: xiatao62@126.com (Tao Xia); xcwan@ahau.edu.cn (Xiaochun Wan); dxli@ahau.edu.cn (Daxiang Li)
2 South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, P.R. China; E-mail: wxy@scbg.ac.cn
* Author to whom correspondence should be addressed; e-mail: lingtj@ahau.edu.cn
Received: 12 August 2006; in revised form: 31 August 2006 / Accepted: 31 August 2006 / Published: 7 September 2006
Full Paper: Cerebrosides from the Roots of Serratula chinensis
Molecules 2006, 11, 677-683 (PDF format 74 K)


Brendan J. O’Keefe and Peter J. Steel*
Department of Chemistry, College of Science, University of Canterbury, Christchurch, New Zealand
* Author to whom correspondence should be addressed; E-mail: peter.steel@canterbury.ac.nz
Received: 31 July 2006; in revised form: 28 August 2006 / Accepted: 29 August 2006 / Published: 13 September 2006
Full Paper: Synthesis and Characterisation of Eight Isomeric Bis(2-pyridyloxy)naphthalenes
Molecules 2006, 11, 684-692 (PDF format 322 K)


Ze Tian ^{1, 2,*}, Yu-Ming Liu ¹, Si-Bao Chen ¹, Jun-Shan Yang ¹, Pei-Gen Xiao ¹, Liao Wang ³ and Erxi Wu  ^2,*
1 Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100094, P.R. China
2 Children’s Hospital Informatics Program at Harvard–MIT Division of Health Sciences and Technology, Children’s Hospital Boston, Harvard Medical School, Boston, MA 02115, U.S.A.
3 College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, P.R. China
* Authors to whom correspondence may be addressed; E-mail: ze.tian@childrens.harvard.edu; Tel: (+86) 1062894597; erxi.wu@childrens.harvard.edu; Tel: (+1) 617-919-2449/Fax: (+1) 617-730-0921
Received: 25 July 2006; in revised form: 28 August 2006 / Accepted: 30 August 2006 / Published: 13 September 2006
Communication: Cytotoxicity of Two Triterpenoids from Nigella glandulifera
Molecules 2006, 11, 693-699 (PDF format 174 K)


Dawei Teng *, Hongxing Zhang and A. Mendonca
Department of Chemistry, ChemRoutes Corporation, Edmonton, Alberta T6E 5P8, Canada
* Author to whom correspondence should be addressed; E-mail: tengdw@yahoo.com
Received: 13 August 2006; in revised form: 6 September 2006 / Accepted: 14 September 2006 / Published: 14 September 2006
Full Paper: An Efficient Synthesis of a Spirocyclic Oxindole Analogue
Molecules 2006, 11, 700-706 (PDF format 67 K)


Samuël Demin, Dirk Van Haver and Pierre J. De Clercq*
Ghent University, Department of Organic Chemistry, Laboratory for Organic Synthesis, Krijgslaan
281 (S4), B-9000 Gent, Belgium
* Author to whom correspondence should be addressed: E-mail: pierre.declercq@UGent.be
Received: 7 September 2006; in revised form: 14 September 2006 / Accepted: 14 September 2006 / Published: 18 September 2006
Full Paper: Asymmetric Synthesis of (7aS)-7a-Methyl-4,5,7,7a-tetrahydro-1H-indene-2,6-dione and Useful Derivatives Thereof
Molecules 2006, 11, 707-713 (PDF format 53 K)


Yonghong Liu ^{1, 2,*}, Jee H. Jung ² Hong Ji ¹ and Si Zhang ¹
1 Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510-301, China
2 College of Pharmacy, Pusan National University, Busan 609-735, Korea
* To whom correspondence should be addressed; e-mail: yonghongliu@scsio.ac.cn
Full Paper: Glycerolipids from a Sarcotragus Species Sponge
Molecules 2006, 11, 714-719 (PDF format 57 K)


Bahador Karami * and Morteza Montazerozohori
Department of Chemistry, Yasouj University, Yasouj 75914-353, Iran
* Author to whom correspondence should be addressed; e-mail: karami@mail.yu.ac.ir
Communication: Tungstate Sulfuric Acid (TSA)/ KMnO₄ as a Novel Heterogeneous System for Rapid Deoximation
Molecules 2006, 11, 720-725 (PDF format 49 K)


Renata Odzak ^1,* and Srdjanka Tomic ²
1 Department of Chemistry, Faculty of Natural Sciences, Mathematics and Education, University of
Split, N. Tesle 12, 21 000 Split, Croatia
2 Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10 000
Zagreb, Croatia; E-mail: stomic@chem.pmf.hr
* Author to whom correspondence should be addressed; E-Mail: rodzak@chem.pmf.hr
Received: 28 July 2006; in revised form: 30 August 2006 / Accepted: 21 September 2006 / Published: 28 September 2006
Communication: Synthesis of New N-Quaternary-3-benzamidoquinuclidinium Salts
Molecules 2006, 11, 726-730 (PDF format 74 K)

Deyanira Angeles-Beltrán ¹, Leticia Lomas-Romero ², Victor H. Lara-Corona ², Eduardo González-Zamora ² and Guillermo Negrón-Silva  ^1,*
1 Departamento de Ciencias Básicas and 2 Departamento de Química, UAM, Av. San Pablo No 180. C. P. 02200, México D. F., México; E-mail addresses: D. Angeles-Beltrán: dab@correo.azc.uam.mx, L. Lomas-Romero: llr@xanum.uam.mx, V. H. Lara-Corona: lacv@xanum.uam.mx, E. González-Zamora: egz@xanum.uam.mx
*Author to whom correspondence should be addressed: e-mail: gns@correo.azc.uam.mx
Received: 21 July 2006; in revised form: 27 September 2006 / Accepted: / Published: 2 October 2006
Full Paper: Sulfated Zirconia-Catalyzed Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (DHPMs) Under Solventless Conditions: Competitive Multicomponent Biginelli vs. Hantzsch Reactions
Molecules 2006, 11, 731-738 (PDF format 83 K)


Zerong Daniel Wang *, Samia O. Sheikh and Yulu Zhang
Department of Chemistry, University of Houston-Clear Lake, 2700 Bay Area Boulevard, Houston, TX 77058, U.S.A., Tel: +1-281-283-3795, Fax: +1-281-283-3709
† Dedicated to the memory of Professor Ramiro Sánchez
* Author to whom correspondence should be addressed; E-mail: wang@uhcl.edu
Received: 9 August 2006; in revised form: 24 August 2006 / Accepted: 24 August 2006 / Published: 2 October 2006
Full Paper: A Simple Synthesis of 2-Thiohydantoins†
Molecules 2006, 11, 739-750 (PDF format 96 K; Supplementary Data PDF format, 1128 K )


Kwang–Chan Ahn ¹, Jae–Chul Jung ² and Oee–Sook Park ^1,*
1 Department of Chemistry, Institute for Basic Sciences, College of Natural Sciences, Chungbuk
National University, Cheongju 361–763, Chungbuk, South Korea.
2 Department of Medicinal Chemistry, School of Pharmacy, University of Mississippi, P.O. Box 1848,
University, Mississippi 38677–1848, USA. E-mail: jcjung@olemiss.edu
* To whom correspondence should be addressed; ospark@chungbuk.ac.kr
Received: 27 September 2006; in revised form: 10 October 2006 / Accepted: 10 October 2006 /Published: 12 October 2006
Full Paper: A Simple and Cost Effective Synthesis of 3,11-Dimethylnonacosan-2-one, A Female Sex Pheromone of the German Cockroach
Molecules 2006, 11, 751-757 (PDF format 48 K)


George A. Kraus ^1,*, Jaehoon Bae ¹, Lankun Wu ² and Eve Wurtele ²
1 Iowa State University Department of Chemistry, Ames, IA 50011, USA. Tel. (+1) 515-294-7794; Fax: (+1) 515-294-0105
2 Iowa State University Department of Genetics, Development and Cell Biology, Ames, IA 50011, USA
* Author to whom correspondence should be addressed; e-mail: gakraus@iastate.edu
Received: 2 September 2006; in revised form: 10 October 2006 / Accepted: 16 October 2006 / Published: 19 October 2006
Full Paper: Synthesis and Natural Distribution of Anti-inflammatory Alkamides from Echinacea
Molecules 2006, 11, 758-767 (PDF format 200 K)


Mehdi Ghandi*, Abolfazl Olyaei and Farshid Salimi
School of Chemistry, University College of Science, University of Tehran, Tehran, Iran.
* Author to whom correspondence should be addressed. E-mail: ghandi@khayam.ut.ac.ir; Tel.: (+98)-
21-61112250; Fax: (+98)-21-66495291.
Received: 28 September 2006; in revised form: 11 October 2006 / Accepted: 12 October 2006 / Published: 19 October 2006
Full Paper: Synthesis of New Unsymmetrical 4,5-Dihydroxy-2-imidazolidinones. Dynamic NMR Spectroscopic Study of the Prototropic Tautomerism in 1-(2-Benzimidazolyl)-3-phenyl-4,5-dihydroxy-2-imidazolidinone
Molecules 2006, 11, 768-775 (PDF format 120 K)


Lakhemici Kaboub, Slimane Fradj and Abdelkrim Gouasmia*
Laboratoire des Matériaux Organiques et Hétérochimie, Département de Chimie, Université de Tébessa, 12000 Tébessa, Algeria
* Author to whom correspondence should be addressed; E-mail: akgouasmia@mail.univ-tebessa.dz, Tel.: (+213)37490062, Fax: (+213)37490268
Received: 26 July 2006; in revised form: 17 September 2006 / Accepted: 10 October 2006 / Published: 21 October 2006
Full Paper: Synthesis and Properties of Novel Unsymmetrical Donor Molecules Containing p-Acetoxy- or p-Hydroxyphenyl Units
Molecules 2006, 11, 776-785 (PDF format 88 K)


Hao Yin ¹, Si Zhang ^1,2,*, Jun Wu ¹, Haihan Nan ¹, Lijuan Long ¹, Jin Yang ¹ and Qingxin Li ¹
1 Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou, 510301, P.R. China, Tel. / Fax: +86 20 89023103; E-mail: yin_hao_gz@hotmail.com
2 Hainan Key Lab of Tropical Marine Biotechnology, Chinese Academy of Science, Sanya, 572000, P.R. China
* Author to whom correspondence should be addressed; E-mail: zhsimd@scsio.ac.cn
Received: 13 September 2006; in revised form 16 October 2006 / Accepted: 16 October 2006 / Published: 20 October 2006
Full Paper: Pongaflavanol: a Prenylated Flavonoid from Pongamia pinnata with a Modified Ring A
Molecules 2006, 11, 786-791 (PDF format 74 K)


Isidro S. Marcos*, María J. Sexmero, Felix A. Hernández, Marta Corrales, Pilar Basabe, David Díez and Julio G. Urones
Departamento de Química Orgánica, Universidad de Salamanca, Plaza de los Caídos 1-5, 37008 Salamanca, Spain
* Author to whom correspondence should be addressed; E-mail: ismarcos@usal.es
Received: 29 September 2006; in revised form: 18 October 2006 / Accepted: 23 October 2006 / Published: 24 October 2006
Full Paper: Synthetic Studies Towards the ent-Labdane Diterpenoids: Rearrangement of ent-Halimanes
Molecules 2006, 11, 792-807 (PDF format 161 K)


M. Letizia Ciavatta ^1,*, M. Pilar Lopez Gresa ², Margherita Gavagnin ¹, Emiliano Manzo ¹, Ernesto Mollo ¹, Lisette D’Souza ³ and Guido Cimino ¹
1 Istituto di Chimica Biomolecolare, CNR, Via Campi Flegrei 34, I 80078-Pozzuoli (Na), Italy; Emails: mgavagnin@icmib.na.cnr.it, emanzo@icmib.na.cnr.it, emollo@icmib.na.cnr.it, gcimino@icmib.na.cnr.it
2 Centro Ecologia Quimica Agricola, Universidad Politecnica Valencia, Campus de Vera, Correos 22012- 46071 Valencia, Spain; E-mail: mplopez@ceqa.upv.es
3 National Institute of Oceanography, CSIR, Dona Paula, 403 004 Goa, India; E-mail: lisette_54@yahoo.com.
* Author to whom correspondence should be addressed; E-mail: lciavatta@icmib.na.cnr.it
Received: 13 September 2006; in revised form: 12 October 2006 / Accepted: 23 October 2006 / Published: 25 October 2006
Full Paper: New Caulerpenyne-derived Metabolites of an Elysia Sacoglossan from the South Indian Coast
Molecules 2006, 11, 808-816 (PDF format 161 K)


Patcharee Pripdeevech ¹, Sugunya Wongpornchai ^1,* and Ampan Promsiri ²
1 Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand
2 Department of Soil Science and Conservation, Faculty of Agriculture, Chiang Mai University, Chiang Mai, 50200, Thailand
* Author to whom correspondence should be addressed; E-mail: scismhth@chiangmai.ac.th. Phone: (+66)-53-943341-5, ext. 120; Fax: (+66)-53-892277
Received: 29 August 2006; in revised form: 12 October 2006 / Accepted: 16 October 2006 / Published: 25 October 2006
Full Paper: Highly Volatile Constituents of Vetiveria zizanioides Roots Grown under Different Cultivation Conditions
Molecules 2006, 11, 817-826 (PDF format 172 K)

Xinyong Liu ^1,*, Renzhang Yan ¹, Niangen Chen ¹, Wenfang Xu ¹, Maria Teresa Molina ² and Salvador Vega ²
1 Institute of Medicinal Chemistry, School of Pharmacy, Shandong University, Jinan 250012, P.R. China
2 Instituto de Quimica Medica (CSIC), c/Juan de la Cierva, 3, 28006 Madrid, Spain
* Author to whom correspondence should be addressed; Xinyong Liu, E-mail: xinyongl@sdu.edu.cn; Tel: (+86)-531-8382005; Fax: (+86)-531-8382264
Received: 5 October 2006; in revised form: 22 October 2006/ Accepted: 23 October 2006 / Published: 1 November 2006
Full Paper: Regioselective Synthesis of Novel N₂- and N₄-Substituted 7-Methylpyrazolo[4,5-e][1,2,4]thiadiazines
Molecules 2006, 11, 827-836 (PDF format 104 K)


Zrinka Rajic 1, Branka Zorc ^1,*, Silvana Raic-Malic ², Katja Ester ³, Marijeta Kralj ³, Krešimir Pavelic ³, Jan Balzarini ⁴, Erik De Clercq ⁴ and Mladen Mintas ^2,*
1 Department of Medicinal Chemistry, Faculty of Pharmacy and Biochemistry, A. Kovačića 1, HR-10000 Zagreb, Croatia; E-mail: zrajic@pharma.hr
2 Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, Marulićev trg 20, HR-10000 Zagreb, Croatia; E-mail: silvana.raic@fkit.hr
3 Division of Molecular Medicine, Ruđer Bošković Institute, Bijenička cesta 54, HR-10000 Zagreb; E-mails: kester@irb.hr, mhorvat@irb.hr, pavelic@irb.hr
4 Rega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-
3000 Leuven, Belgium; E-mail: jan.balzarini@rega.kuleuven.ac.be, erik.declercq@rega.kuleuven.be
* Authors to whom correspondence should be addressed; Branka Zorc: bzbz@pharma.hr; Phone: (+385) 1 4856202, Fax: (+385) 1 4856201; Mladen Mintas: mladen.mintas@fkit.hr; Phone: (+385) 1 4597214, Fax: (+385) 1 4597224
Received: 6 October 2006; in revised form: 25 October 2006 / Accepted: 25 October 2006 / Published: 1 November 2006
Full Paper: Hydantoin Derivatives of L- and D-amino acids: Synthesis and Evaluation of Their Antiviral and Antitumoral Activity
Molecules 2006, 11, 837-848 (PDF format 104 K)


Fu-Min Zhang ^1,†, Xiao-Jun Yao ^1,‡, Xuan Tian ^1,2,* and Yong-Qiang Tu ^1,*
1 State Key Laboratory of Applied Organic Chemistry & Department of Chemistry, Lanzhou University, Lanzhou, 730000, P. R. China. Tel: (+86) 931-8912410; Fax: (+86) 931-8912582; E-mails: †zhangfm@lzu.edu.cn; ‡xjyao@lzu.edu.cn
2 Xinjiang Production & Construction Corps Key Laboratory of Protection and Utilization of Biological Resources in Tarim Basin, Tarim, Xinjiang, P.R. China.
* Authors to whom correspondence should be addressed. E-mails: xuant@lzu.edu.cn or tuyq@lzu.edu.cn
Received: 27 September 2006; in revised form: 26 October 2006 / Accepted: 27 October 2006 / Published: 2 November 2006
Full Paper: Synthesis and Biological Evaluation of New 4β-5-Fu-substituted 4'-Demethylepipodophyllotoxin Derivatives
Molecules 2006, 11, 849-857 (PDF format 100 K)


Augusto Rivera ^1,*, Jaime Ríos-Motta ¹ and Francisco León ²
1 Departamento de Química, Universidad Nacional de Colombia, Ciudad Universitaria, Carrera 30 # 45-03, Bogotá-D.C., Colombia. Tel.: (+57)-1-3165000; Fax: (+57)-1-3165220.
2 Instituto Universitario de Bio-Orgánica-Instituto de Productos Naturales y Agrobiología, Avenida Astrofísico Francisco Sánchez, 2, 38206, La Laguna, Tenerife, Spain
* Author to whom correspondence should be addressed. E-mail: ariverau@unal.edu.co
Received: 13 September 2006; in revised form: 9 October 2006 / Accepted: 10 October 2006 / Published: 11 November 2006
Full Paper: Revisiting the Reaction Between Diaminomaleonitrile and Aromatic Aldehydes: a Green Chemistry Approach
Molecules 2006, 11, 858-866 (PDF format 66 K)


Fátima C. Teixeira ^1,*, Hélène Ramos ¹, Inês F. Antunes ¹, M. João M. Curto ¹, M. Teresa Duarte ² and Isabel Bento ³
1 INETI - Departamento de Tecnologia de Indústrias Químicas, Estrada do Paço do Lumiar, 22, 1649-038 Lisboa, Portugal
2 Instituto Superior Técnico, Centro de Química Estrutural, Complexo I, Av. Rovisco Pais, 1049-001 Lisboa, Portugal
3 Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Apartado 127, 2781-901 Oeiras, Portugal
* Author to whom correspondence should be addressed; E-mail: fatima.teixeira@ineti.pt
Received: 4 October 2006; in revised form: 30 October 2006 / Accepted: 13 November 2006 / Published: 14 November 2006
Full Paper: Synthesis and Structural Characterization of 1- and 2-Substituted Indazoles: Ester and Carboxylic Acid Derivatives
Molecules 2006, 11, 867-889 (PDF format 171 K)


Yehya Mahmoud Elkholy * and Mohamed Abdelhamed Morsy
Chemistry Department, Faculty of Science, Helwan University, Helwan, Cairo, Egypt
* Author to whom correspondence should be addressed; e-mail: Y_elkholy@ yahoo.com
Received: 18 October 2006; in revised form: 7 November 2006 / Accepted: 7 November 2006 / Published: 17 November 2006
Full Paper: Facile Synthesis of 5, 6, 7, 8-Tetrahydropyrimido [4, 5-b]-quinoline Derivatives
Molecules 2006, 11, 890-903 (PDF format 146 K)


Tudor Rosu ^1,*, Simona Pasculescu ¹